Landscape → Musculoskeletal

Gout

153 clinical trials

41 active

153 total (since 2015)

Phase 1 Active

52 total

Phase 2 Active

59 total

Phase 3 Active

28 total

Phase 4 Active

27 total

Top Sponsors (Industry)

Sorted by active Active Done Failed

Arthrosi Therapeutics 3 3 0

Jiangsu HengRui Medicine Co., Ltd. 2 10 0

Atom Therapeutics Co., Ltd 2 6 1

Amgen 2 6 0

Crystalys Therapeutics 2 0 0

Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd. 2 0 0

Shanton Pharma Pte. Ltd. 2 0 0

InventisBio Co., Ltd 1 3 0

Innovent Biologics (Suzhou) Co. Ltd. 1 2 0

Protalix 1 1 0

Shanghai Institute Of Biological Products 1 1 0

Innovent Biologics Technology Limited (Shanghai R&D Center) 1 0 0

Intelligem Therapeutics Australia Pty Ltd. 1 0 0

Olatec Therapeutics LLC 1 0 0

Novo Nordisk 1 0 0

NCT07388498 RECRUITING

A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

Amgen n=270

NCT07089875 RECRUITING

A Study of Dotinurad Versus Allopurinol in Participants With Gout

Crystalys Therapeutics n=500

NCT07414394 NOT YET RECRUITING

Tigulixostat (IBI128) vs Febuxostat in Gout

Innovent Biologics Technology Limited (Shanghai R&D Center) n=600

NCT07089888 RECRUITING

A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

Crystalys Therapeutics n=250

NCT05109936 RECRUITING

Immediate Prescription of a Hypouricemic Treatment, Febuxostat, Compared to Its Delayed Administration

University Hospital, Rouen n=128

NCT05658575 RECRUITING

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Olatec Therapeutics LLC n=300

NCT06846515 ACTIVE NOT RECRUITING

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301)

Arthrosi Therapeutics n=750

NCT06439602 ACTIVE NOT RECRUITING

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-302)

Arthrosi Therapeutics n=750

NCT06863701 RECRUITING

Efficacy Anda Safety of Etoricoxib With Betamethasone for the Treatment of Acute Gout Arthritis

Laboratorios Silanes S.A. de C.V. n=72

NCT06603142 ACTIVE NOT RECRUITING

Phase II/III Study of AR882 Capsules Compared to Febuxostat Tablets in Patients with Primary Gout and Hyperuricemia

Guangzhou Ruianbo Pharmaceutical Technology Co., Ltd n=636

NCT06414837 NOT YET RECRUITING

Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Jiangsu HengRui Medicine Co., Ltd. n=434

NCT06068478 COMPLETED

A Study to Evaluate Efficacy and Safety of Qingzhu Granules in the Treatment of Acute Gouty Arthritis

Tasly Pharmaceutical Group Co., Ltd n=472

NCT05818085 COMPLETED

Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout

Atom Therapeutics Co., Ltd n=300

NCT04596540 COMPLETED

A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy II

Swedish Orphan Biovitrum n=153

NCT05586958 COMPLETED

Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients

LG Chem n=354

NCT06139393 COMPLETED

Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Jiangsu HengRui Medicine Co., Ltd. n=765

NCT04513366 COMPLETED

A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy

Swedish Orphan Biovitrum n=112

NCT05007392 COMPLETED

A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout

Eisai Co., Ltd. n=451

NCT05586971 COMPLETED

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients

LG Chem n=2,202

NCT06276556 TERMINATED

Extension Study of ABP-671 in Participants With Gout

Atom Therapeutics Co., Ltd n=43

NCT04517253 TERMINATED

A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS

Eli Lilly and Company n=10

NCT04956432 COMPLETED

A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout

Jiangsu HengRui Medicine Co., Ltd. n=779

NCT05983445 COMPLETED

Safety & Efffficacy of Genakumab in Patients With Frequent Flares

Changchun GeneScience Pharmaceutical Co., Ltd. n=313

NCT04052932 COMPLETED

A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gout

Jiangsu HengRui Medicine Co., Ltd. n=594

NCT02578394 COMPLETED

Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Study

Mid and South Essex NHS Foundation Trust n=21

NCT03006445 COMPLETED

Study of FYU-981 in Hyperuricemia With or Without Gout

Fuji Yakuhin Co., Ltd. n=330

NCT03100318 COMPLETED

Benzbromarone-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout

Fuji Yakuhin Co., Ltd. n=201

NCT03372200 COMPLETED

Febuxostat-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout

Mochida Pharmaceutical Company, Ltd. n=203

NCT07116746 RECRUITING

Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients

Arthrosi Therapeutics

NCT07280156 RECRUITING

A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

Protalix

NCT07362355 NOT YET RECRUITING

The Efficacy and Safety of SHR4640 Tablet Combined With 40 mg Febuxostat Tablets in the Treatment of Primary Gout and Hyperuricemia

Jiangsu HengRui Medicine Co., Ltd.

NCT06310967 RECRUITING

A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease

Intelligem Therapeutics Australia Pty Ltd.

NCT07145229 RECRUITING

Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare

Atom Therapeutics Co., Ltd

NCT06924658 RECRUITING

Metformin in Safety and Efficacy in Gouty Patients

Mostafa Bahaa

NCT06995339 RECRUITING

Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients

Mostafa Bahaa

NCT05665699 ACTIVE NOT RECRUITING

Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout

InventisBio Co., Ltd

NCT06956885 NOT YET RECRUITING

Maintenance or Withdrawal of Urate Lowering Therapy According to Ultrasound Features in Gout Patients: a Randomised Controlled Trial Stop Treatment In Gout

Assistance Publique - Hôpitaux de Paris

NCT05613868 ACTIVE NOT RECRUITING

TPN-101 in Aicardi-Goutières Syndrome (AGS)

Transposon Therapeutics, Inc.

NCT05574036 ACTIVE NOT RECRUITING

Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia

Tanta University

NCT06729853 ACTIVE NOT RECRUITING

PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function

Shanton Pharma Pte. Ltd.

NCT05690204 ACTIVE NOT RECRUITING

Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.

Shanton Pharma Pte. Ltd.

NCT04844814 SUSPENDED

Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantation

Assistance Publique - Hôpitaux de Paris

NCT03921554 COMPLETED

JAK Inhibitor Treatment in AGS

Adeline Vanderver, MD

NCT03934099 COMPLETED

A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia

LG Chem

NCT02363452 COMPLETED

Reverse Transcriptase Inhibitors in AGS

Assistance Publique - Hôpitaux de Paris

NCT03304717 WITHDRAWN

Reverse Transcriptase Inhibitors in Aicardi Goutières Syndrome

Children's Hospital of Philadelphia

NCT06501534 COMPLETED

A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjects

Innovent Biologics (Suzhou) Co. Ltd.

NCT05328531 COMPLETED

Clinical Study of Genakumab for Injection in Patients With Acute Gout

Changchun GeneScience Pharmaceutical Co., Ltd.

NCT05253833 COMPLETED

Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout

Arthrosi Therapeutics

NCT06056570 COMPLETED

Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia

Urica Therapeutics Inc.

NCT05936281 COMPLETED

A Study of the Efficacy of Genakumab in Prevention of Acute Flares in Gout Patients Initiating Urate-lowering TherapyUrate-lowering (GenSci048-202)

Changchun GeneScience Pharmaceutical Co., Ltd.

NCT05936268 COMPLETED

Safety and Efficacy of Genakumab for Injection in Patients With Gout Flare

Changchun GeneScience Pharmaceutical Co., Ltd.

NCT05504083 COMPLETED

Evaluate the Efficacy and Safety of D-0120 in Primary Hyperuricemia Patients

InventisBio Co., Ltd

NCT04731103 COMPLETED

Inhibition of Reverse Transcription in Aicardi-Goutières Syndrome

University of Edinburgh

NCT05256810 TERMINATED

A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

Alnylam Pharmaceuticals

NCT03905512 COMPLETED

A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Participants Refractory to Conventional Therapy

Selecta Biosciences, Inc.

NCT03648996 COMPLETED

Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid

University of Missouri-Columbia

NCT04987294 TERMINATED

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease

Allena Pharmaceuticals

NCT04987242 COMPLETED

An Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)

Allena Pharmaceuticals

NCT05119686 COMPLETED

Phase 2b Evaluation of Efficacy and Safety of AR882 in Gout Patients

Arthrosi Therapeutics

NCT04638543 COMPLETED

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of ABP-671 in Patients With Gout or Hyperuricemia

Atom Therapeutics Co., Ltd

NCT04067492 TERMINATED

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Evaluation of RPH-104 Administered at Different Doses to Patients With Acute Gout Attack

R-Pharm

NCT04130204 COMPLETED

Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS)

Dyve Biosciences, Inc.

NCT03923868 COMPLETED

D-0120 Safety and PK/PD Study in China

InventisBio Co., Ltd

NCT03303989 COMPLETED

REduCing Immunogenicity to PegloticasE (RECIPE) Study

University of Alabama at Birmingham

NCT02959918 COMPLETED

Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid

Selecta Biosciences, Inc.

NCT04040816 COMPLETED

Placebo Controlled, Multiple Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAP-001 in Gout Patients

Shanton Pharma Co., Ltd.

NCT02903446 COMPLETED

Denosumab In Addition To Intense Urate-Lowering Therapy for Bone Erosions

University of Alabama at Birmingham

NCT02598596 COMPLETED

Tolerization Reduces Intolerance to Pegloticase and Prolongs the Urate Lowering Effect

Ampel BioSolutions, LLC

NCT03865407 TERMINATED

Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease

Virginia Commonwealth University

NCT04804111 COMPLETED

Study of of URC102 to Assess the Efficacy and Safety in Gout Patients

JW Pharmaceutical

NCT04155918 COMPLETED

Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients

Arthrosi Therapeutics

NCT03002974 COMPLETED

A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritis

Swedish Orphan Biovitrum

NCT03118739 COMPLETED

Intensive Uric Acid Lowering With Verinurad and Febuxostat in Patients With Albuminuria

AstraZeneca

NCT03316131 COMPLETED

A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA

AstraZeneca

NCT03185793 COMPLETED

Dose-finding and Safety Study of SHR4640 in Subjects With Hyperuricemia

Jiangsu HengRui Medicine Co., Ltd.

NCT02837198 COMPLETED

Study of FYU-981 in Hyperuricemia (Effect on Two Hyperuricemic Types)

Fuji Yakuhin Co., Ltd.

NCT02498652 COMPLETED

Phase 2a RDEA3170 and Allopurinol Combination Study in Gout Subjects

Ardea Biosciences, Inc.

NCT02416167 COMPLETED

Study of FYU-981 in Hyperuricemia With or Without Gout

Fuji Yakuhin Co., Ltd.

NCT02557126 COMPLETED

Study of URC102 to Assess the Safety and Efficacy in Gout Patients

JW Pharmaceutical

NCT02330796 COMPLETED

Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout

Revive Therapeutics, Ltd.

NCT07367971 NOT YET RECRUITING

Drug-Drug Interaction Study of ABP-671 in Gout Patients

Atom Therapeutics Co., Ltd

NCT07346027 NOT YET RECRUITING

Safety and Food Effect on Single-Dose Bioavailability of F-02-2-Na in Healthy Adult Subjects

Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd.

NCT06298071 RECRUITING

A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.

Shanghai Institute Of Biological Products

NCT07324434 ENROLLING BY INVITATION

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult Subjects

Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd.

NCT07295496 RECRUITING

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetic of IBI3011

Innovent Biologics (Suzhou) Co. Ltd.

NCT06859073 RECRUITING

A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia

Novo Nordisk A/S

NCT06629376 RECRUITING

Safety, Tolerability, and Pharmacokinetic Characteristics of SSS11 in Patients With Gout and Hyperuricemia

Shenyang Sunshine Pharmaceutical Co., LTD.

NCT06444867 COMPLETED

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

LEO Pharma

NCT06186219 COMPLETED

Recapturing Immune Tolerance to Pegloticase for the Management of Tophaceous Gout

University of California, Los Angeles

NCT06258213 COMPLETED

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral ABP-745 Administration in Healthy Volunteers

Atom Therapeutics Co., Ltd

NCT05745727 COMPLETED

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Protalix

NCT06451848 COMPLETED

A Bioequivalence Study of Two Different Dosage Form of Genakumab

Changchun GeneScience Pharmaceutical Co., Ltd.

NCT06678581 COMPLETED

SAD,MAD and Food Effect Study of SAP-001 Tablets in Chinese Subjects

Shanton Pharma Co., Ltd.

NCT04622124 COMPLETED

A Safety and Tolerability Study of FCN-207 in Healthy Volunteers

Fochon Pharmaceuticals, Ltd.

NCT05954169 COMPLETED

Pharmacokinetic/Pharmacokinetic and Safety Studies of SHR4640 in Subjects With Moderate Renal Insufficiency and Healthy Subjects

Jiangsu HengRui Medicine Co., Ltd.

NCT06277752 COMPLETED

A Study to Investigate the Pharmacokinetic/Pharmacodynamic Characteristics of IBI128(A New Xanthine Oxidase Inhibitor)

Innovent Biologics (Suzhou) Co. Ltd.

NCT06196580 COMPLETED

PK Effects of SHR4640 on Repaglinide and Midazolam, and the Impact of SHR4640 on QT Interval

Jiangsu HengRui Medicine Co., Ltd.

NCT06168929 COMPLETED

Bioequivalence Study of 2 Sizes of SHR4640 Tablets Orally in Healthy Subjects

Jiangsu HengRui Medicine Co., Ltd.

NCT06189404 COMPLETED

Effect of Tigulixostat on the Pharmacokinetics of Theophylline

LG Chem

NCT05302388 COMPLETED

A Study Exploring Efficacy of Pegloticase in Subjects With Asymptomatic Hyperuricemia

Shanghai Institute Of Biological Products

NCT04040907 COMPLETED

The the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of XNW3009 in Health Subject

Evopoint Biosciences Inc.

NCT05168683 COMPLETED

Scintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tablets

Allena Pharmaceuticals

NCT04886050 COMPLETED

Relative Bioavailability Study to Assess an LC350189 Tablet Compared to an LC350189 Capsule in Healthy Adults

LG Chem

NCT03857165 COMPLETED

Placebo Controlled, Dose Escalation Study to Evaluate Safety, Pharmacokinetics & Efficacy of SAP-001 in Gout Patients

Shanton Pharma Co., Ltd.

NCT04236219 COMPLETED

ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers

Allena Pharmaceuticals

NCT04829435 COMPLETED

Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)

Allena Pharmaceuticals

NCT04066712 COMPLETED

Renal PK Study of LC350189

LG Chem

NCT03906006 COMPLETED

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy Subjects

Atom Therapeutics Co., Ltd

NCT03927677 COMPLETED

The Effect of Colchicine on the Pharmacokinetic Profile of LC350189 in Healthy Aldults.

LG Chem

NCT04070846 COMPLETED

Mass Balance Study of [14C]LC350189 in Healthy Volunteers

LG Chem

NCT04139824 COMPLETED

The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults

LG Chem

NCT04303039 COMPLETED

Study to Investigate the Effects of Food on Relative Bioavailability of ABP-671 Tablets in Healthy Subjects

Atom Therapeutics Co., Ltd

NCT04060173 COMPLETED

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671

Atom Therapeutics Co., Ltd

NCT03131583 COMPLETED

The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout

Jiangsu HengRui Medicine Co., Ltd.

NCT03291782 COMPLETED

D-0120 Safety and PK/PD, Food Effect Study in Healthy Volunteers

InventisBio Co., Ltd

NCT03272425 COMPLETED

Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.

Ardea Biosciences, Inc.

NCT03375632 COMPLETED

Study of FYU-981 in Hyperuricemic Outpatients With or Without Gout (Effect on Two Hyperuricemic Types)

Mochida Pharmaceutical Company, Ltd.

NCT03015948 COMPLETED

A Single Dose Study of SHR4640 in Healthy Male Volunteers

Atridia Pty Ltd.

NCT03211403 COMPLETED

Multiple Doses Study of SHR4640 in Male Subjects With High Serum Uric Acid Level

Atridia Pty Ltd.

NCT02890966 COMPLETED

Multiple Dose Study of SHR4640 in Healthy Subjects

Jiangsu HengRui Medicine Co., Ltd.

NCT02815839 COMPLETED

Single Dose Study of SHR4640 in Healthy Subjects

Jiangsu HengRui Medicine Co., Ltd.

NCT02648269 COMPLETED

Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels

Selecta Biosciences, Inc.

NCT02464605 COMPLETED

Safety and Pharmacodynamics of SEL-037 (Pegsiticase) in Subjects With Elevated Blood Uric Acid Levels

Selecta Biosciences, Inc.

NCT02608710 COMPLETED

RDEA3170 PK/PD Study

Ardea Biosciences, Inc.

NCT02374164 COMPLETED

Food Effect Study of Febuxostat XR in Healthy Participants

Takeda

NCT07369622 NOT YET RECRUITING

HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness

Haiphong University of Medicine and Pharmacy

NCT07346079 RECRUITING

Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares

Massachusetts General Hospital

NCT06229145 ACTIVE NOT RECRUITING

A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout

Amgen

NCT06834230 RECRUITING

Effect of Dotinurad in Hyperuricemia With Hypertension

Saga University

NCT04875702 RECRUITING

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Massachusetts General Hospital

NCT06674109 NOT YET RECRUITING

SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial

Massachusetts General Hospital

NCT06966635 RECRUITING

Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets

Huashan Hospital

NCT05698680 RECRUITING

Prednisolone Versus Colchicine for Acute Gout in Primary Care

University Medicine Greifswald

NCT06622603 NOT YET RECRUITING

The Effects of Febuxostat Dose Tapering in Gout Patients Optimally Controlled for 5 Years or More

Seoul National University Hospital

NCT06463561 RECRUITING

CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea

Hospital Universitario La Paz

NCT04511702 COMPLETED

Infusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in Subjects With Uncontrolled Gout Receiving Methotrexate

Amgen

NCT04762498 COMPLETED

A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)

Amgen

NCT06718062 COMPLETED

Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia

Hansung University

NCT04772313 COMPLETED

Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy

Amgen

NCT03994731 COMPLETED

Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout

Amgen

NCT03635957 COMPLETED

Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout

Amgen

NCT04087720 COMPLETED

Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant

Amgen

NCT03933007 TERMINATED

Relation Between Blood Concentration of Colchicine and Response to Colchicine Treatment in Gout Flare

Assistance Publique - Hôpitaux de Paris

NCT02579096 COMPLETED

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

VA Office of Research and Development

NCT03636373 TERMINATED

Pilot Study Evaluating The Efficacy Of Etanercept In Acute Gout

Rutgers, The State University of New Jersey

NCT05474560 COMPLETED

Febuxostat Versus Allopurinol on Hepatic Steatosis in MAFLD Patients

Ain Shams University

NCT02462421 TERMINATED

Pharmacogenetics of SGLT2 Inhibitors

University of Maryland, Baltimore

NCT03226899 TERMINATED

A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment

Ironwood Pharmaceuticals, Inc.

NCT04161872 COMPLETED

Nutraceutical on Hyperuricemia

University of Pavia

NCT02956278 COMPLETED

The Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics

University of California, San Francisco

NCT02500641 COMPLETED

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout

Menarini International Operations Luxembourg SA

NCT02477488 COMPLETED

Optimal Administration of Allopurinol in Dialysis Patients

Maisonneuve-Rosemont Hospital

Data: ClinicalTrials.gov