TheraRadar

Pharma Intelligence, Simplified

Landscape Oncology

Hematologic Malignancies

989 clinical trials

516 active
/
989 total (since 2015)
261
Phase 1 Active
533 total
309
Phase 2 Active
555 total
55
Phase 3 Active
86 total
6
Phase 4 Active
18 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Johnson & Johnson 10 9 4
Novartis 6 3 2
Orca Biosystems, Inc. 4 0 0
Incyte Corporation 3 0 3
OncoVerity, Inc. 3 2 0
Eli Lilly 3 1 0
Merck 3 0 1
Kura Oncology, Inc. 3 1 0
Bristol-Myers Squibb 2 10 9
Bellicum Pharmaceuticals 2 0 3
Daiichi Sankyo 2 1 1
Sumitomo Pharma America, Inc. 2 1 0
Newave Pharmaceutical Inc 2 1 0
Ascentage Pharma Group Inc. 2 1 0
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2 1 0
NCT05316701 ACTIVE NOT RECRUITING
Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
Orca Biosystems, Inc. n=187
NCT06578247 RECRUITING
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
Daiichi Sankyo n=700
NCT03486873 RECRUITING
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Merck Sharp & Dohme LLC n=3,500
NCT05947851 RECRUITING
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
Merck Sharp & Dohme LLC n=735
NCT05602194 RECRUITING
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma
Children's Oncology Group n=440
NCT03959085 RECRUITING
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Children's Oncology Group n=5,951
NCT03007147 ACTIVE NOT RECRUITING
Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Children's Oncology Group n=475
NCT04708054 RECRUITING
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
M.D. Anderson Cancer Center n=324
NCT02339740 ACTIVE NOT RECRUITING
Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia
Children's Oncology Group n=158
NCT05254743 RECRUITING
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Loxo Oncology, Inc. n=662
NCT03462719 ACTIVE NOT RECRUITING
A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Janssen Research & Development, LLC n=211
NCT04256317 RECRUITING
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Taiho Oncology, Inc. n=236
NCT07186192 RECRUITING
Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy
City of Hope Medical Center n=190
NCT06852222 RECRUITING
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Janssen Research & Development, LLC n=600
NCT05327894 RECRUITING
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
Princess Maxima Center for Pediatric Oncology n=160
NCT07321652 NOT YET RECRUITING
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
Alliance for Clinical Trials in Oncology n=466
NCT07296445 NOT YET RECRUITING
A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301)
SDK Therapeutics, Inc. n=120
NCT05457556 ACTIVE NOT RECRUITING
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Children's Oncology Group n=435
NCT06449586 ACTIVE NOT RECRUITING
CMV-specific T Cell Immunity Test Indicated Prophylaxis of Letermovir After All-HSCT
Ruijin Hospital n=250
NCT06647862 RECRUITING
IMM01+Azacitidine VS Placebo +Azacitidine in Patients With Newly Diagnosed Chronic Myelomonocytic Leukemia (CMML1-2)
ImmuneOnco Biopharmaceuticals (Shanghai) Inc. n=170
NCT06378138 RECRUITING
ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (APEX-03)
Beijing InnoCare Pharma Tech Co., Ltd. n=226
NCT03173248 ACTIVE NOT RECRUITING
Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation
Institut de Recherches Internationales Servier n=146
NCT07202065 RECRUITING
Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Dosing Immunoglobulin (Dose Ig)
Monash University n=900
NCT07202052 RECRUITING
Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT)
Monash University n=900
NCT07202078 RECRUITING
Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Starting Immunoglobulin (Start Ig)
Monash University n=900
NCT07202091 RECRUITING
Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig)
Monash University n=900
NCT03057054 ACTIVE NOT RECRUITING
Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant
Children's Oncology Group n=173
NCT07157514 NOT YET RECRUITING
Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML
Actinium Pharmaceuticals n=306
NCT07152041 RECRUITING
Newly-diagnosed Pediatric Ph-positive B-ALL Protocol
Institute of Hematology & Blood Diseases Hospital, China n=150
NCT04307576 RECRUITING
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Mats Heyman n=6,430
NCT06882057 RECRUITING
Newly-diagnosed Low Risk Pediatric B-cell ALL Protocol
Institute of Hematology & Blood Diseases Hospital, China n=3,000
NCT06855810 RECRUITING
Newly-diagnosed Pediatric T-cell ALL Protocol
Institute of Hematology & Blood Diseases Hospital, China n=610
NCT02521493 ACTIVE NOT RECRUITING
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
Children's Oncology Group n=280
NCT07082452 NOT YET RECRUITING
A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive Induction
Gustave Roussy, Cancer Campus, Grand Paris n=262
NCT06401356 RECRUITING
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
Novartis Pharmaceuticals n=50
NCT05586074 RECRUITING
HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML
Sunshine Lake Pharma Co., Ltd. n=324
NCT04547049 RECRUITING
A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies
First Affiliated Hospital of Zhejiang University n=176
NCT05883956 ACTIVE NOT RECRUITING
A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia
Otsuka Australia Pharmaceutical Pty Ltd n=13
NCT04090736 ACTIVE NOT RECRUITING
Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy
PETHEMA Foundation n=302
NCT02600208 ACTIVE NOT RECRUITING
Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies with Alpha Beta TCell and B Cell Depletion Using the CliniMACS Device
Julie-An M. Talano n=60
NCT06764238 RECRUITING
Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol
Institute of Hematology & Blood Diseases Hospital, China n=1,800
NCT06756152 RECRUITING
Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis
Federal Research Institute of Pediatric Hematology, Oncology and Immunology n=50
NCT04608318 ACTIVE NOT RECRUITING
Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients with Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
German CLL Study Group n=897
NCT06673459 NOT YET RECRUITING
BuCy Vs. TBICy for Allo-HSCT in T-ALL Patients
The First Affiliated Hospital of Soochow University n=430
NCT06607419 RECRUITING
Efficacy Study of Blinatumomab Clean Up Early Residual Disease for Newly Diagnosed Pediatric B Lymphoblastic Leukemia
Shanghai Jiao Tong University School of Medicine n=90
NCT06475820 ACTIVE NOT RECRUITING
Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis
Federal Research Institute of Pediatric Hematology, Oncology and Immunology n=150
NCT06544109 ENROLLING BY INVITATION
Venetoclax for Prevention of Differentiation Syndrom in Acute Promyelocytic Leukemia Patients
The First Affiliated Hospital of Soochow University n=98
NCT06434467 NOT YET RECRUITING
The Efficacy and Safety of Nelarabine Injection in Patients With T-lymphoblastic Leukemia and T-lymphoblastic Lymphoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. n=83
NCT06381817 RECRUITING
Haplo-cord HCT vs. Haplo-HCT for T-ALL Patients
The First Affiliated Hospital of Soochow University n=146
NCT06278896 NOT YET RECRUITING
Early Neutropenic Fever De-escalation of Antibiotics Study
Brigham and Women's Hospital n=260
NCT05328258 RECRUITING
Use of GnRHa During Chemotherapy for Fertility Protection
Kenny Rodriguez-Wallberg n=500
NCT05515029 ACTIVE NOT RECRUITING
Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis
Federal Research Institute of Pediatric Hematology, Oncology and Immunology n=56
NCT05313958 RECRUITING
Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University n=43
NCT02665065 ACTIVE NOT RECRUITING
Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
Actinium Pharmaceuticals n=153
NCT03793517 RECRUITING
Decitabine Plus mBU/CY for High Risk Acute Leukemia With MRD Pre-HSCT
Peking University People's Hospital n=55
NCT02730299 COMPLETED
Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDS
Gamida Cell ltd n=125
NCT03926624 TERMINATED
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
Delta-Fly Pharma, Inc. n=167
NCT04266301 TERMINATED
Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2)
Novartis Pharmaceuticals n=530
NCT02421939 COMPLETED
A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation
Astellas Pharma Global Development, Inc. n=371
NCT03268954 COMPLETED
Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML)
Takeda n=454
NCT06940570 SUSPENDED
Methadone as an Alternative Treatment for Children Underdoing HSCT
University of Texas Southwestern Medical Center n=60
NCT06108739 TERMINATED
ATG Plus Low-dose PT-Cy for GVHD Prevention
Peking University People's Hospital n=66
NCT02577406 COMPLETED
An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation
Celgene n=319
NCT03016130 TERMINATED
Comparing Two Diets in Patients Undergoing HSCT or Remission Induction Chemo for Acute Leukemia and MDS (UF-BMT-LDND-101)
University of Florida n=217
NCT02688140 COMPLETED
Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia
Technische Universität Dresden n=135
NCT03595800 COMPLETED
Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen
Institut Paoli-Calmettes n=9
NCT02907359 COMPLETED
Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs
Astex Pharmaceuticals, Inc. n=417
NCT02348489 COMPLETED
SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction
Astex Pharmaceuticals, Inc. n=815
NCT03306264 COMPLETED
Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AML
Astex Pharmaceuticals, Inc. n=227
NCT02326311 COMPLETED
Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients ≥60 Years in Deep Molecular Response
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia n=229
NCT02668653 COMPLETED
Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)
Daiichi Sankyo n=539
NCT02393859 COMPLETED
Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)
Amgen n=111
NCT03959241 COMPLETED
TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)
Medical College of Wisconsin n=431
NCT06205290 WITHDRAWN
A Study to Compare the Efficacy and Safety of Lisocabtagene Maraleucel vs Investigator's Choice Options in Adult Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, Whose Disease Has Failed Treatment With Both BTKi and BCL2i Therapies
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
NCT04842604 COMPLETED
Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML
Pfizer n=14
NCT04145531 COMPLETED
An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)
Jazz Pharmaceuticals n=229
NCT00488605 WITHDRAWN
H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis
University of New Mexico
NCT02890784 COMPLETED
Dasatinib Holiday for Improved Tolerability
University of Jena n=291
NCT03800758 COMPLETED
Expressive Helping for Stem Cell Transplant Patients
Northwestern University n=405
NCT03416179 COMPLETED
A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia
Pfizer n=730
NCT02942173 COMPLETED
CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT
Federal Research Institute of Pediatric Hematology, Oncology and Immunology n=150
NCT02345850 COMPLETED
Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301)
National Heart, Lung, and Blood Institute (NHLBI) n=346
NCT02545283 TERMINATED
A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Hoffmann-La Roche n=447
NCT03825887 COMPLETED
Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients
Children's Cancer Hospital Egypt 57357 n=80
NCT02696408 COMPLETED
Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation
Institut de Cancérologie de la Loire n=234
NCT02472145 COMPLETED
An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy
Janssen Research & Development, LLC n=326