NCT06823375 RECRUITING SBRT With Immunotherapy and Atezo-Bev in HCC With Major Portal Vein Thrombosis
Chinese University of Hong Kong
NCT06530251 RECRUITING A Study of AK112 in Patients With Advanced Hepatocellular Carcinoma (HCC)
Akeso
NCT06811116 RECRUITING Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial
National Cancer Institute (NCI)
NCT03419481 ACTIVE NOT RECRUITING Pembrolizumab in Hepatocellular Carcinoma
CCTU
NCT05211323 ACTIVE NOT RECRUITING A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer
National Cancer Institute (NCI)
NCT04588051 ACTIVE NOT RECRUITING Cabozantinib in Hepatocellular Carcinoma
Stephen Chan Lam
NCT07291076 RECRUITING A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
Bristol-Myers Squibb
NCT02867592 ACTIVE NOT RECRUITING Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors
National Cancer Institute (NCI)
NCT06218420 RECRUITING Evaluation of Stereotactic Body Radiotherapy as a Bridge Therapy for Hepatocellular Carcinoma Patients Enlisted for Liver Transplantation
Assistance Publique - Hôpitaux de Paris
NCT07447050 RECRUITING Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
University of California, Irvine
NCT02968810 ACTIVE NOT RECRUITING Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis
National Cancer Institute (NCI)
NCT05063565 ACTIVE NOT RECRUITING TheraSphere With Durvalumab and Tremelimumab for HCC
Boston Scientific Corporation
NCT04524871 RECRUITING A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Hoffmann-La Roche
NCT06789848 RECRUITING Ligufalimab and Cadonilimab in Advanced Liver Cancers
University of Texas Southwestern Medical Center
NCT04008797 ACTIVE NOT RECRUITING A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor
Eisai Inc.
NCT05441475 ENROLLING BY INVITATION A Phase 2, Open-Label Study of ABSK-011 Combined Atezolizumab or SOC in HCC Patients
Abbisko Therapeutics Co, Ltd
NCT04851119 RECRUITING Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Children's Oncology Group
NCT03942328 RECRUITING Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer
Mayo Clinic
NCT04134559 RECRUITING Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma
Allison O'Neill, MD
NCT05969860 RECRUITING At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Mayo Clinic
NCT07422753 NOT YET RECRUITING A Prospective, Randomized Study of TACE Combined With Sintilimab, Bevacizumab, and Ipilimumab N01 Treating Advanced HCC
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04522544 RECRUITING Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCC
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT05468359 RECRUITING Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients
St. Jude Children's Research Hospital
NCT07410676 RECRUITING EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Essen Biotech
NCT05775159 RECRUITING Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
AstraZeneca
NCT05669339 RECRUITING AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma
University of Florida
NCT07410494 RECRUITING Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Essen Biotech
NCT02519348 ACTIVE NOT RECRUITING A Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma
MedImmune LLC
NCT07413354 RECRUITING Tislelizumab Combined With Huaier Granule as First-line Treatment for Unresectable Hepatocellular Carcinoma
Tongji Hospital
NCT07412054 NOT YET RECRUITING Lenvatinib and Pembrolizumab With or Without BCAA in Unresectable HCC
Fudan University
NCT06027086 RECRUITING DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07405086 NOT YET RECRUITING Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study
OHSU Knight Cancer Institute
NCT03519997 ACTIVE NOT RECRUITING A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma
David Hsieh
NCT05919264 RECRUITING FOG-001 in Locally Advanced or Metastatic Solid Tumors
Parabilis Medicines, Inc.
NCT07223307 RECRUITING REGULUS: MRI-guided Adaptive SABR for Liver Cancers
Stanford University
NCT03937830 ACTIVE NOT RECRUITING Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma
National Cancer Institute (NCI)
NCT06679985 RECRUITING A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma
Coherus Oncology, Inc.
NCT06096779 RECRUITING A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis
Genentech, Inc.
NCT07381634 NOT YET RECRUITING The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related Toxicities
First Affiliated Hospital of Wenzhou Medical University
NCT07380633 ACTIVE NOT RECRUITING Toripalimab Plus Bevacizumab Combined Three Intra-arterial Therapies (TACE, HAIC, or TACE-HAIC) for Unresectable Hepatocellular Carcinoma: a Phase 2, Multicenter Randomised Non-comparative Trial
Sun Yat-sen University
NCT06553885 RECRUITING Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC
H. Lee Moffitt Cancer Center and Research Institute
NCT05113186 ACTIVE NOT RECRUITING Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative
Assistance Publique - Hôpitaux de Paris
NCT06084884 ACTIVE NOT RECRUITING A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma
AstraZeneca
NCT07174570 RECRUITING Celecoxib, Durvalumab and Tremelimumab for the Treatment of Patients With Advanced or Metastatic Liver Cancer
Emory University
NCT07363356 NOT YET RECRUITING Drug Sensitivity Testing-Based Tumor Organoids to Guide Adjuvant Therapy After Hepatectomy for Primary Liver Cancer
Eastern Hepatobiliary Surgery Hospital
NCT07363512 NOT YET RECRUITING Efficacy and Safety of Radiotherapy Combined With Tislelizumab and Anlotinib in the Treatment of Hepatocellular Carcinoma Complicated With Portal Vein Tumor Thrombus
Henan Cancer Hospital
NCT05842174 NOT YET RECRUITING Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma
VA Office of Research and Development
NCT05705492 RECRUITING Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
OHSU Knight Cancer Institute
NCT04550481 ACTIVE NOT RECRUITING Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study
Northwestern University
NCT07331883 RECRUITING Sintilimab Combined With Bevacizumab Biosimilar as Adjuvant Treatment After Resection of Ruptured Hepatocellular Carcinoma (CLEAR-2)
Ruijin Hospital
NCT03539822 RECRUITING Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies
Anwaar Saeed
NCT07328009 NOT YET RECRUITING A Platform Trial for Personalized and Adaptive Therapies in Hepatocellular Carcinoma
Fudan University
NCT07352007 NOT YET RECRUITING Sintilimab Combined With Stereotactic Body Radiotherapy as Neoadjuvant Therapy for Resectable Hepatocellular
Lei ZHAO
NCT05366829 RECRUITING Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma
Rutgers, The State University of New Jersey
NCT06040099 ACTIVE NOT RECRUITING A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE
AstraZeneca
NCT07314372 NOT YET RECRUITING FAD Subtype-Guided Combination Therapy for Unresectable Hepatocellular Carcinoma
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT07351513 NOT YET RECRUITING A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Hepatocellular Carcinoma
Eastern Hepatobiliary Surgery Hospital
NCT07350070 NOT YET RECRUITING TACE Combined With Tislelizumab, Lenvatinib, and Carvedilol for Unresectable HCC With Cirrhotic Portal Hypertension
Tongji Hospital
NCT07175441 RECRUITING Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma
Riboscience, LLC.
NCT07324824 RECRUITING Sintilimab Plus Bevacizumab Biosimilar as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma
Sun Yat-sen University
NCT07341737 NOT YET RECRUITING SL-28 for Advanced Solid Tumours
Second Life Therapeutics
NCT03228667 ACTIVE NOT RECRUITING QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
ImmunityBio, Inc.
NCT04380545 RECRUITING Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer
M.D. Anderson Cancer Center
NCT07337421 RECRUITING Efcacy and Safety of Postoperative Adjuvant Hepatic Arterial Infusion Chemotherapy With mFOLFOX in Hepatocellular Carcinoma With High-risk Recurrence Factors
Northern Jiangsu People's Hospital
NCT07337460 RECRUITING Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors
Northern Jiangsu People's Hospital
NCT05651022 ACTIVE NOT RECRUITING Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors
Indaptus Therapeutics, Inc
NCT07334483 RECRUITING A Study of Yttrium [90Y] Microsphere Injection in Combination With Targeted Immunotherapy in the Treatment of HCC
GrandPharma (China) Co., Ltd.
NCT07327034 RECRUITING ABSK-011+BSC vs. Placebo+BSC in Previously Treated Advanced HCC With FGF19 Overexpression
Abbisko Therapeutics Co, Ltd
NCT07297654 NOT YET RECRUITING First-Line Lenvatinib in Child-Pugh B Patients With HCC Unsuitable for Curative Treatment
National Cancer Center, Korea
NCT07324473 NOT YET RECRUITING Ivarmacitinib Combined With Camrelizumab and Apatinib for Unresectable Advanced Hepatocellular Carcinoma With Acquired Resistance to Immune Checkpoint Therapy: A Single-Arm Exploratory Clinical Study
First Affiliated Hospital of Chongqing Medical University
NCT07324304 RECRUITING NWRD06 DNA Plasmid for HCC After Curative Resection.
Newish Technology (Beijing) Co., Ltd.
NCT06526104 RECRUITING Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis
The University of Texas Health Science Center at San Antonio
NCT07317414 RECRUITING β-alanine in the Treatment of Advanced Hepatocellular Carcinoma
Peking Union Medical College Hospital
NCT03727633 RECRUITING Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion
University Hospital, Montpellier
NCT06590246 RECRUITING A Study to Evaluate C-CAR031 in Glypican-3 (GPC3)+ Advanced/Recurrent Hepatocellular Carcinoma (HCC)
Shanghai AbelZeta Ltd.
NCT07312292 NOT YET RECRUITING Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT)
Niek Wijnen
NCT07081633 RECRUITING Durvalumab and Tremelimumab With Lenvatinib as First-line Treatment in Patients With Unresectable Hepatocellular Carcinoma
AstraZeneca
NCT07310173 RECRUITING Phase IIb Study of AST-3424 in Patients With AKR1C3-high Expressing Advanced Hepatocellular Carcinoma
Zhejiang Hisun Pharmaceutical Co. Ltd.
NCT06828380 RECRUITING A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion
National Cancer Center, Korea
NCT07285044 RECRUITING The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Mayo Clinic
NCT06880523 RECRUITING STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma
Canadian Cancer Trials Group
NCT07227012 RECRUITING A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
Pfizer
NCT05257590 RECRUITING CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular Carcinoma
TaiRx, Inc.
NCT07282509 NOT YET RECRUITING Safety and Efficacy of Paclitaxel Liposome Arterial Infusion Combined With Systemic Therapy for Second-Line Treatment of Advanced Liver Cancer
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT05733598 RECRUITING Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC
Replimune Inc.
NCT07179900 NOT YET RECRUITING Radiotherapy Combined With QL1706 and Bevacizumab for Unresectable Non-metastatic Hepatocellular Carcinoma
Hebei Medical University Fourth Hospital
NCT07276100 RECRUITING Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and Bevacizumab
IRCCS Azienda Ospedaliero-Universitaria di Bologna
NCT07274774 RECRUITING SBRT Plus Systemic Therapy vs Systemic Therapy Alone in BCLC C Hepatocellular Carcinoma
Shandong Cancer Hospital and Institute
NCT07053072 RECRUITING PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.
West China Hospital
NCT06254248 NOT YET RECRUITING Safety of Atezolizumab-Bevacizumab in Liver Transplanted Patients With Advanced Hepatocellular Carcinoma
Assistance Publique - Hôpitaux de Paris
NCT04430452 RECRUITING Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular Carcinoma
Mary Feng, MD
NCT04864054 RECRUITING T-Cell Therapy (ECT204) in Adults With Advanced HCC
Eureka Therapeutics Inc.
NCT05120271 ACTIVE NOT RECRUITING BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
Sotio Biotech Inc.
NCT06265285 RECRUITING Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
Mayo Clinic
NCT07070518 RECRUITING Study of GV20-0251 in Participants With Solid Tumor Malignancies
GV20 Therapeutics
NCT04204850 RECRUITING Cabozantinib to Treat Recurrent Liver Cancer Post Transplant
University Health Network, Toronto
NCT06902246 RECRUITING Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma
University of Miami
NCT07260058 NOT YET RECRUITING Immune Cell Therapy for Advanced Solid Tumors
Liaoning Medical Diagnosis and Treatment Technology Research and Development Co., Ltd.
NCT07157969 RECRUITING ICIs and Anti-VEGF Antibody/TKIs With or Without Interventional Therapy for Advanced HCC
Peking Union Medical College Hospital
NCT06795022 RECRUITING First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours
AstraZeneca
NCT07239245 RECRUITING Study to Evaluate the Efficacy and Safety of Neo-Adjuvant TACE and Atezolizumab Plus Bevacizumab Therapy for High-Risk Recurrent Hepatocellular Carcinamo
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06400160 NOT YET RECRUITING Clinical Trial of TB511 in Advanced Solid Tumors
Twinpig Biolab, Inc.
NCT06632717 RECRUITING Hepatic Arterial Infusion Chemotherapy With Lipiodol Embolization in Advanced Hepatocellular Carcinoma
National Taiwan University Hospital
NCT07246668 RECRUITING A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma
Yonsei University
NCT07239986 NOT YET RECRUITING A Phase 2 Study of BB102 in Patients With Hepatocellular Carcinoma
Broadenbio Ltd., Co.
NCT05751343 RECRUITING Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial
Sun Yat-sen University
NCT04175912 ACTIVE NOT RECRUITING Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver
National Cancer Institute (NCI)
NCT07230314 NOT YET RECRUITING Sequential Transarterial Chemoembolization (TACE), Stereotactic Body Radiation Therapy (SBRT), and Immune Checkpoint Inhibitors for Unresectable Hepatocellular Carcinoma Treated With Donafenib
Jinling Hospital, China
NCT06521567 ACTIVE NOT RECRUITING A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
GlaxoSmithKline
NCT06503146 RECRUITING 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
National Cancer Institute (NCI)
NCT07223424 RECRUITING Patient Preference for Subcutaneous vs. Intravenous Immune Therapy
Diwakar Davar
NCT07226063 NOT YET RECRUITING Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular Cancer
Amit Mahipal
NCT06698250 RECRUITING Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)
Anwaar Saeed
NCT05440708 RECRUITING A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
Tvardi Therapeutics, Incorporated
NCT07219459 NOT YET RECRUITING Visugromab, Nivolumab and a Tyrosine Kinase Inhibitor (TKI) Compared to Double Placebo and a TKI in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure
CatalYm GmbH
NCT07209813 NOT YET RECRUITING GKL-006 Combined With TACE in Treatment of Unresectable Hepatocellular Carcinoma
Beijing Gene Key Life Technology Co., Ltd
NCT07145801 RECRUITING Y-90 Treatment Response Using Transarterial Radioembolization
Thomas Jefferson University
NCT06789757 RECRUITING The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC)
Inova Health Care Services
NCT05377034 RECRUITING Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients
National Cancer Centre, Singapore
NCT04727307 RECRUITING Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial
University Hospital, Montpellier
NCT06526338 RECRUITING Adjuvant IP-001 Treatment for HCC Patients Following Surgical Resection and Ablation or Ablation Alone
Robert C. Martin
NCT06349317 RECRUITING Neoadjuvant IMRT Combined With Camrelizumab and Apatinib for Resectable HCC With PVTT
Yongyi Zeng
NCT06467799 RECRUITING Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC
Sun Yat-sen University
NCT07192185 RECRUITING Systemic Chemotherapy With FOLFOX Plus Atezolizumab & Bevacizumab for Patients With Advanced HCC Who Previously Received Atezolizumab & Bevacizumab
Sun Yat-sen University
NCT07192848 NOT YET RECRUITING Adebrelimab + Apatinib in Advanced HCC Post-Systemic Therapy
Song Peng
NCT06852820 NOT YET RECRUITING 68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)
Melissa Lumish
NCT04912765 RECRUITING Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
National Cancer Centre, Singapore
NCT04721132 ACTIVE NOT RECRUITING Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer
M.D. Anderson Cancer Center
NCT07187284 NOT YET RECRUITING EDN Combined With TACE/HAIC and Second-Line Immune-Targeted Treatment Versus TACE/HAIC Alone in Locally Advanced HCC With Portal Vein Tumor Thrombosis After First-Line Therapy Failure: A Prospective, Multicenter, Randomized Controlled Trial
Zhongda Hospital
NCT06205706 ACTIVE NOT RECRUITING BI-1910 as a Single Agent and in Combination With Pembrolizumab for the Treatment of Advanced Solid Tumors
BioInvent International AB
NCT06362369 RECRUITING A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
7 Hills Pharma, LLC
NCT05168163 RECRUITING Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer
Academic and Community Cancer Research United
NCT07168668 NOT YET RECRUITING Partial Immune-boost TACE in unrEseCTable HCC Patients Under Systemic Treatment
Chang Gung Memorial Hospital
NCT05528952 RECRUITING Evaluation of the Interest to Combine a CD4 Th1-inducer Cancer Vaccine Derived From Telomerase and Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma
Centre Hospitalier Universitaire de Besancon
NCT06999694 RECRUITING Proton Radiotherapy Plus Tremelimumab/Durvalumab for BCLC Stage B and C HCC
Chang Gung Memorial Hospital
NCT07157306 NOT YET RECRUITING Gecacitinib Combined With Donafenib and PD-1 Inhibitor as Immune Rechallenge Therapy for Unresectable Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT05194293 ACTIVE NOT RECRUITING Regorafenib and Durvalumab for the Treatment of High-Risk Liver Cancer
Academic and Community Cancer Research United
NCT07154082 RECRUITING Apatinib Mesylate and Camrelizumab Combined With TACE as Neoadjuvant Therapy for Hepatocellular Carcinoma
Wei Zhang
NCT06902389 RECRUITING A Clinical Study of Multi-target Hi-TCR-T Cells in the Treatment of Advanced Hepatocellular Carcinoma
Eastern Hepatobiliary Surgery Hospital
NCT07151326 NOT YET RECRUITING Cabozantinib for Progressive HCC Post-first-line Immuno-oncologic Combination Therapy
National Health Research Institutes, Taiwan
NCT07150377 NOT YET RECRUITING A Phase II Single-Arm Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Lenvatinib and TACE for Advanced Hepatocellular Carcinoma
The Second Affiliated Hospital of Shandong First Medical University
NCT07099274 RECRUITING Lparomlimab and Tuvonralimab Injection in Combination With TACE and Lenvatinib in the Treatment of Second-Line Therapy for Unresectable Intermediate-to-Advanced Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT07138885 ACTIVE NOT RECRUITING A Phase II, Single-Arm, Prospective Trial on the Efficacy and Safety of QL1706 Combination Regimen as Second-Line Therapy for Targeted-Immunotherapy-Resistant Hepatocellular Carcinoma
Sun Yat-sen University
NCT07131501 NOT YET RECRUITING A Single-Arm, Multicenter, Exploratory Clinical Study of TACE Combined With Iparomlimab and Tuvonralimab Injection (QL1706) and Lenvatinib for Perioperative Treatment of Resectable Hepatocellular Carcinoma
The First Affiliated Hospital with Nanjing Medical University
NCT06986785 RECRUITING A Study of BL-B01D1 Combined With Lenvatinib in Patients With Advanced Hepatocellular Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd.
NCT07128251 NOT YET RECRUITING A Single-Arm, Multicenter, Exploratory Clinical Study of Transarterial Chemoembolization (TACE) Combined With Iparomlimab and Tuvonralimab Injection and Bevacizumab Injection for the Treatment of Unresectable, Non-Metastatic Hepatocellular Carcinoma (HCC)
Anhui Provincial Hospital
NCT07100392 RECRUITING Tauroursodeoxycholic Acid (TUDCA) Plus Camrelizumab and Regorafenib in Hepatocellular Carcinoma Previously Treated With Anti-PD1/PD-L1 and Bevacizumab
Fudan University
NCT05822752 ACTIVE NOT RECRUITING Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)
AbbVie
NCT07122089 NOT YET RECRUITING Evaluation of SIRT Followed by Immunotherapy for Treatment of Hepatocellular Carcinoma With Portal Vein Thrombosis
Center Eugene Marquis
NCT07123545 RECRUITING Autologous Neoantigen-Specific T-Cell Therapy for Advanced Hepatocellular Carcinoma
Zhejiang University
NCT07010497 NOT YET RECRUITING A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular Carcinoma
Asan Medical Center
NCT07119931 NOT YET RECRUITING A Clinical Study Evaluating HAIC Combined With Iparomlimab and Tuvonralimab Injection Plus Bevacizumab in Patients With Initially Potentially Resectable Hepatocellular Carcinoma (ITBHaic Study)
Tianjin Medical University Cancer Institute and Hospital
NCT06294548 RECRUITING A Study of Valemetostat Tosylate (DS-3201b) With Atezolizumab and Bevacizumab in HCC
University of Alabama at Birmingham
NCT05057013 ACTIVE NOT RECRUITING A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours
Cancer Research UK
NCT05690048 RECRUITING Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA)
Michael Dill
NCT06551272 RECRUITING Microbiota Modification for Immuno-oncology in Hepatocellular Carcinoma
Center Eugene Marquis
NCT06695026 RECRUITING A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 in Combination With Valganciclovir (VGCV) and Atezolizumab/Bevacizumab in Subjects With Hepatocellular Carcinoma
Rznomics, Inc.
NCT06819566 RECRUITING Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCC
Asan Medical Center
NCT06031285 RECRUITING Perioperative Sintilimab Plus Bevacizumab Biosimilar and TACE-HAIC for HCC Patients With PVTT: A Phase-2 Clinical Trial
Sun Yat-sen University
NCT07078305 NOT YET RECRUITING Comparing the Combination of Trastuzumab and Regorafenib With Regorafenib Monotherapy for Advanced Hepatocellular Carcinoma After First-line Treatment
Tianjin Medical University Cancer Institute and Hospital
NCT07075419 NOT YET RECRUITING JDB153 Combined With Penpulimab for Hepatocellular Carcinoma After Standard Treatment Failure
West China Hospital
NCT05095519 ACTIVE NOT RECRUITING Hepatocellular Carcinoma Imaging Using PSMA PET/CT
Peter MacCallum Cancer Centre, Australia
NCT07064668 NOT YET RECRUITING Tauroursodeoxycholic Acid Combined With PD-1/PD-L1 Immunotherapy in Advanced Hepatocellular Carcinoma: A Prospective Study
Tongji Hospital
NCT07062055 RECRUITING BRAVE Study: QL1706 + Bevacizumab + SBRT for BCLC-C HCC With PVTT or Oligometastases
Shandong Cancer Hospital and Institute
NCT07053488 RECRUITING CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC
NCT05797805 RECRUITING A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma
Iterion Therapeutics
NCT07052253 NOT YET RECRUITING A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.
Akeso
NCT07047586 RECRUITING Lenvatinib Plus Tislelizumab Versus Lenvatinib Alone in Hepatocellular Carcinoma Previously Treated With Anti-PD1/PD-L1 and Bevacizumab
Fudan University
NCT03093688 RECRUITING Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor
Shanghai Public Health Clinical Center
NCT06954467 RECRUITING JS207 Combined With JS007 as First-line Treatment for Advanced Hepatocellular Carcinoma
Shanghai Junshi Bioscience Co., Ltd.
NCT07042919 NOT YET RECRUITING Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer
Northwestern University
NCT06580002 RECRUITING Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
University of California, Irvine
NCT05516628 RECRUITING Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma
National Cancer Centre, Singapore
NCT06773845 RECRUITING Building Evidence for Ablative Internal Radiation Therapy in Localized HCC Beyond the Up-To-7 Criteria
Seoul National University Hospital
NCT07018947 NOT YET RECRUITING Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC
Fundacion Clinic per a la Recerca Biomédica
NCT06954116 NOT YET RECRUITING Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence
Tongji Hospital
NCT04118114 RECRUITING Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors
National Cancer Centre, Singapore
NCT07014150 NOT YET RECRUITING Neoadjuvant Therapy of iIparomlimab and Tuvonralimab Combined With Lenvatinib for Hepatocellular Carcinoma
Peking Union Medical College Hospital
NCT07012798 NOT YET RECRUITING FOLFOX Combined With Durvalumab (MEDI4736), Bevacizumab, and Stereotactic Body Radiotherapy in Sequential Treatment of Potentially Resectable Locally Advanced Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT06999707 RECRUITING Photon Radiotherapy Plus Tremelimumab/Durvalumab for BCLC Stage B and C HCC
Chang Gung Memorial Hospital
NCT04954339 ACTIVE NOT RECRUITING DYNAmic Immune Microenvironment of HCC Treated With atezolIzumab Plus bevaCizumab
Tae Won Kim
NCT05024214 RECRUITING Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors
3D Medicines (Sichuan) Co., Ltd.
NCT06995105 RECRUITING Personalized Tumor Neoantigen mRNA Therapy for Advanced Hepatocellular Carcinoma
Zhejiang University
NCT06741020 RECRUITING Hepatic Arterial Infusion Chemotherapy and Immunotherapy for Hepatocellular Carcinoma
Zhejiang Cancer Hospital
NCT06984718 NOT YET RECRUITING A Phase II Study of AK104 Combination With Lenvatinib Versus Lenvatinib for Second-line HCC
Akeso
NCT05724563 ACTIVE NOT RECRUITING Domvanalimab and Zimberelimab in Advanced Liver Cancers
University of Texas Southwestern Medical Center
NCT06978933 RECRUITING FGF19 Overexpression Combination Unified Study in HCC-19
RenJi Hospital
NCT06280105 RECRUITING A Trial of Cadonilimab Plus Regorafenib in Patients With Hepatocellular Carcinoma Who Failed Camrelizumab Combined With Apatinib
Meng Chao Hepatobiliary Hospital of Fujian Medical University
NCT06339424 RECRUITING Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma
Chang Gung Memorial Hospital
NCT06605664 RECRUITING Hyperpolarized 13C-MRI in Patients With Hepatocellular Carcinoma Undergoing Radiotherapy, Atezolizumab, and Bevacizumab
Chang Gung Memorial Hospital
NCT06911255 RECRUITING Safety and Efficacy of Tremelimumab+Durvalumab(MEDI4736)+TACE in Unresectable Hepatocellular Carcinoma
Yoon Jun Kim
NCT06958484 NOT YET RECRUITING Iparomlimab and Tuvonralimab Injection (QL1706) Combined With Bevacizumab for Postoperative Adjuvant Therapy in Hepatocellular Carcinoma (HCC) With High Risk of Recurrence
The Affiliated Hospital of Xuzhou Medical University
NCT04965454 RECRUITING Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma
Queen's Medical Center
NCT03107416 ACTIVE NOT RECRUITING Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells
Memorial Sloan Kettering Cancer Center
NCT06420440 RECRUITING Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model
Chen Xiaoping
NCT04472767 RECRUITING Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma
University of California, Irvine
NCT06904183 RECRUITING Lenvatinib, Sintilimab, and DEB-TACE With/Without HAIC for HCC >7 cm With PVTT
Second Affiliated Hospital of Guangzhou Medical University
NCT06904196 RECRUITING Lenvatinib Plus SIRT vs Lenvatinib in TACE-Refractory HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT05964361 ACTIVE NOT RECRUITING First-in-human Interleukin-15-transpresenting Wilms' Tumor Protein 1-targeting Autologous Dendritic Cell Vaccination in Cancer Patients
University Hospital, Antwerp
NCT06166576 RECRUITING Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis
Seoul National University Hospital
NCT04829383 ACTIVE NOT RECRUITING A Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma
Howard S Hochster
NCT03916627 ACTIVE NOT RECRUITING Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients
Regeneron Pharmaceuticals
NCT04196465 ACTIVE NOT RECRUITING Phase II Study of Neoadjuvant Immune Checkpoint Inhibitor in Patients With Resectable Gastrointestinal Cancers
Asan Medical Center
NCT04634357 RECRUITING ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma
Eureka Therapeutics Inc.
NCT05901194 ACTIVE NOT RECRUITING Lenvatinib Treatment in Waiting List of Liver Transplantation After TACE Failure in Patients With Hepatocellular Carcinoma
Assistance Publique - Hôpitaux de Paris
NCT06045975 RECRUITING Durvalumab/Tremelimumab in Neoadjuvant and Adjuvant Setting in Patients With HCC Treated by by Percutaneous Ablation Procedure
Assistance Publique - Hôpitaux de Paris
NCT06904014 RECRUITING Efficacy and Safety of Sintilimab Combined With Lenvatinib and HAIC for Neoadjuvant Therapy of Borderline Resectable HCC
Lei ZHAO
NCT06896396 NOT YET RECRUITING Icaritin Soft Capsules+TACE+Immunotherapy+Targeted Therapy Versus TACE+Immunotherapy+Targeted Therapy for Unresectable Hepatocellular Carcinoma
Zhiyong Huang
NCT06860490 RECRUITING HAIC Combined with Sintilimab Plus Bevacizumab Biosimilar for Advanced Hepatocellular Carcinoma (TASK-03)
Fudan University
NCT04294498 ACTIVE NOT RECRUITING Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection
National Taiwan University Hospital
NCT03899428 RECRUITING Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCC
Humanity & Health Medical Group Limited
NCT05873244 RECRUITING CXD101 in Immunotherapy-related Liver Cancer
Stephen Chan Lam
NCT04802876 ACTIVE NOT RECRUITING Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors
SOLTI Breast Cancer Research Group
NCT06884982 NOT YET RECRUITING An Exploratory Clinical Study on Neoadjuvant Treatment of Hepatocellular Carcinoma with QL1706 Combined with Lenvatinib
Northern Jiangsu People's Hospital
NCT05864105 ACTIVE NOT RECRUITING PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma
Biotheus Inc.
NCT05319431 ACTIVE NOT RECRUITING A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC
Akeso
NCT05901519 RECRUITING A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma
University of Michigan Rogel Cancer Center
NCT06870942 RECRUITING Efficacy and Safety of Radiotherapy in Oligoprogressive HCC Following First-line PD-1 Therapy
Shanghai Zhongshan Hospital
NCT05195294 NOT YET RECRUITING Study of HBV-TCR T Cells (LioCyx-M) as Monotherapy or as Combination With Lenvatinib for HBV-related HCC
Lion TCR Pte. Ltd.
NCT06742892 RECRUITING A Phase II Clinical Study to Evaluate HLX43 in Patients With Locally Advanced or Metastatic HCC Failed or Intolerance to Standard Therapy
Shanghai Henlius Biotech
NCT06867432 NOT YET RECRUITING Efficacy and Safety of Yttrium-90 Microspheres Selective Internal Radiotherapy Combined with Immune Checkpoint Inhibitors and Anti-angiogenesis Drugs Sequential HAIC for Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT05304481 RECRUITING Efficacy and Safety of Activated T Lymphocytes (ATL) in Hepatocellular Carcinoma
Lukas Biomedical Inc.
NCT06478719 RECRUITING To Evaluate Safety and Efficacy of FB-1603 in Hepatocellular Carcinoma Patient Receiving Transarterial Chemoembolization
Febico Biomedical Corp.
NCT05057845 RECRUITING Cryoablation Combined with Tislelizumab Plus Lenvatinib As Second-line or Later Therapy in Advanced Hepatocellular Carcinoma
Fudan University
NCT06239155 ACTIVE NOT RECRUITING A Phase I/II Study of AST-3424 in Subjects With Advanced Solid Tumors
Ascentawits Pharmaceuticals, Ltd
NCT05992220 RECRUITING Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion
Asan Medical Center
NCT06397235 RECRUITING DEB-TACE+RALOX-HAIC vs DEB-TACE for Large HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT06133062 RECRUITING Atezolizumab and Bevacizumab with Proton Radiotherapy for Unresectable Hepatocellular Carcinoma
Chang Gung Memorial Hospital
NCT05417932 RECRUITING A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma
SCG Cell Therapy Pte. Ltd.
NCT05920863 RECRUITING Lenvatinib Combined with Tislelizumab and TACE Applied As Neoadjuvant Regimen for the Patients of CNLC Stage IB and IIA Hepatocellular Carcinoma with High-risk Recurrence Factors
Zhejiang Cancer Hospital
NCT04114136 RECRUITING Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
Dan Zandberg
NCT06812039 RECRUITING HAIC Combined with Donafenib and Sintilimab As Perioperative Treatment for Resectable Hepatocellular Carcinoma Patients At High Risk of Recurrence
Fudan University
NCT04251117 ACTIVE NOT RECRUITING GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects with Advanced HCC
Geneos Therapeutics
NCT06707233 RECRUITING Y-90 SIRT for Unresectable HCC Larger Than 7cm
Second Affiliated Hospital of Guangzhou Medical University
NCT04123379 ACTIVE NOT RECRUITING Neoadjuvant Nivolumab with CCR2/5-inhibitor or Anti-IL-8) for Non-small Cell Lung Cancer (NSCLC) or Hepatocellular Carcinoma (HCC)
Icahn School of Medicine at Mount Sinai
NCT06422403 RECRUITING A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
National University Hospital, Singapore
NCT06766643 RECRUITING Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer
Tianjin Medical University Cancer Institute and Hospital
NCT04615143 RECRUITING Tislelizumab or Tislelizumab Combined With Lenvatinib Neo-adjuvant Treatment for Resectable RHCC
Sun Yat-sen University
NCT06762782 RECRUITING Clinical Study on the Effectiveness and Safety of Lenvatinib As Adjuvant Treatment for Patients with High-risk Recurrence of Hepatocellular Carcinoma After Surgery
The First Affiliated Hospital with Nanjing Medical University
NCT06178198 RECRUITING Radiation Major Hepatectomy to Selectively Treat Large Unifocal Hepatocellular Carcinoma
Seoul National University Hospital
NCT06114082 RECRUITING TACE Using Idarubicin Versus Doxorubicin Chemoemulsion in Patients with Hepatocellular Carcinoma
Seoul National University Hospital
NCT03033446 ACTIVE NOT RECRUITING Study of Y90-Radioembolization With Nivolumab in Asians With Hepatocellular Carcinoma
National Cancer Centre, Singapore
NCT06446154 RECRUITING Fruquintinib After ICIs Treatment in Unresectable Hepatocellular Carcinoma
Sun Yat-sen University
NCT05103904 RECRUITING Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant
Emory University
NCT05435014 RECRUITING T-ACE Oil by TAE/TACE in Patients With Hepatocellular Carcinoma
T-ACE Medical Co., Ltd
NCT06737913 RECRUITING HAI or IV of Adebrelimab, Combined with Bevacizumab and HAI of FOLFOX for Advanced Unresectable Hepatocellular Carcinoma
Sun Yat-sen University
NCT06742424 RECRUITING PD-L1 Antibody + Bevacizumab With Hepatic Arterial Infusion Chemotherapy for Advanced HCC
West China Hospital
NCT06349980 RECRUITING A Study to Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 with or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients.
Shanghai Henlius Biotech
NCT06725121 RECRUITING Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant
University Health Network, Toronto
NCT06584071 NOT YET RECRUITING A Study to Evaluate of PM8002 Combined With PM1009 in Patients With First-line HCC
Biotheus Inc.
NCT06558227 RECRUITING Study of ZG005 Combined With Bevacizumab Versus Sintilimab Combined With Bevacizumab in Advanced Hepatocellular Carcinoma
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NCT06187961 RECRUITING Combined HAIC, Lenvatinib and Cadonilimab As Conversion Therapy for Unresectable Hepatocellular Carcinoma
Tongji Hospital
NCT06724263 NOT YET RECRUITING A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors
Tasly Biopharmaceuticals Co., Ltd.
NCT05185739 RECRUITING Perioperative Pembrolizumab and Lenvatinib in Resectable Hepatocellular Carcinoma (HCC)
University College, London
NCT03869034 ACTIVE NOT RECRUITING HAIC Combined with PD-1 Inhibitor in Potentially Resectable Locally Advanced HCC
Sun Yat-sen University
NCT05625893 RECRUITING Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion
Samsung Medical Center
NCT05475613 RECRUITING Downstaging Protocol Containing Immunotherapy for HCC Beyond the Milan Criteria Before Liver Transplantation
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT05824975 RECRUITING A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
GI Innovation, Inc.
NCT05027425 ACTIVE NOT RECRUITING Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant
Davendra Sohal
NCT03259867 RECRUITING Combination of TATE and PD-1 Inhibitor in Liver Cancer
Teclison Ltd.
NCT03812874 RECRUITING A Study of PTX-9908 Injection for Non-resectable HCC with TACE
TCM Biotech International Corp.
NCT06301399 RECRUITING Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study
Tianjin Medical University Cancer Institute and Hospital
NCT06313190 RECRUITING Combination of SBRT and Immunotherapy in Small Hepatocellular Carcinoma (HSBRT2402)
Sun Yat-sen University
NCT03680508 ACTIVE NOT RECRUITING TSR-022 (anti-TIM-3 Antibody) and TSR-042 (anti-PD-1 Antibody) in Patients with Liver Cancer
University of Hawaii
NCT06685354 NOT YET RECRUITING Sequential T and I With H101 Via HAI for BCLC C Stage HCC: A Prospective Single-Center Single-Arm Pilot Study
Henan Cancer Hospital
NCT05595473 ACTIVE NOT RECRUITING A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 with Valganciclovir (VGCV) in Subjects with Hepatocellular Carcinoma
Rznomics, Inc.
NCT06664996 RECRUITING Sintilimab Combined SBRT As Neoadjuvant Therapy for Resectable HCC with PVTT
West China Hospital
NCT06646198 RECRUITING TIPS Plus Half-dose Donafenib in AHCC with PVTT-associated Portal Hypertension
Fei Gao
NCT06641453 NOT YET RECRUITING CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular Carcinoma
Chinese PLA General Hospital
NCT05882370 RECRUITING TIPS Plus Cadonilimab in Advanced HCC with Tumor Thrombosis-associated Portal Hypertension:a Prospective, Single-arm, Phase II Study
Fei Gao
NCT05620134 ACTIVE NOT RECRUITING Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer
Salubris Biotherapeutics Inc
NCT05440864 RECRUITING Durvalumab and Tremelimumab in Resectable HCC
University Health Network, Toronto
NCT06632522 NOT YET RECRUITING Clinical Study of Radiotherapy Combined With Camrelizumab and Apatinib in the Treatment of Liver Cancer Patients .
Beijing Tsinghua Chang Gung Hospital
NCT06607107 RECRUITING mFOLFOX7 Plus Camrelizumab and Apatinib in BCLC Stage A/B Hepatocellular Carcinoma Patients Beyond Milan Criteria
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06592612 NOT YET RECRUITING Second-line Systemic Therapy Combined with SBRT for HCC with Oligoprogression After Standard First-line Systemic Treatment
Sun Yat-sen University
NCT04770207 RECRUITING Intra-tumor Injection of Drug-eluting Microspheres With Multiple Drugs
Second Affiliated Hospital of Guangzhou Medical University
NCT06563947 NOT YET RECRUITING Single Arm Clinical Trial (Gut Microbiota and HCC)
Xu Yong, MD
NCT06563934 NOT YET RECRUITING Gut Microbiota in Liver Cancer (Treated With TKIs In Combination With ICIs)
Xu Yong, MD
NCT06463522 RECRUITING Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma
Beijing 302 Hospital
NCT06309485 NOT YET RECRUITING Phase 2 Study of WGI-0301 for Advanced HCC
Zhejiang Haichang Biotech Co., Ltd.
NCT06546280 NOT YET RECRUITING A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
Zhujiang Hospital
NCT05223816 RECRUITING An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma
Virogin Biotech Canada Ltd
NCT06538935 NOT YET RECRUITING SBRT Combined With Adbelimumab and Apatinib for Perioperative and Conversion Therapy of Hepatocellular Carcinoma
Fujian Cancer Hospital
NCT06535737 NOT YET RECRUITING A Phase 2, Single Arm Study of Cabozantinib in Patients With Hepatocellular Carcinoma Who Have Received Prior Atezolizumab and Bevacizumab
Chulalongkorn University
NCT04483284 ACTIVE NOT RECRUITING Study of TACE Combined With Camrelizumab in the Treatment of HCC Patients
Shanghai Zhongshan Hospital
NCT06454578 RECRUITING Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection
Qilu Hospital of Shandong University
NCT06530784 NOT YET RECRUITING Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
NCT06527495 RECRUITING Clinical Pharmacogenetic Study of Sorafenib in Egyptian Patients With Hepatocellular Carcinoma
Assiut University
NCT06524466 ACTIVE NOT RECRUITING Neoadjuvant SBRT Combined With Lenvatinib and Pucotenlimab for Resectable Hepatocellular Carcinoma
Sun Yat-sen University
NCT06518434 RECRUITING A Pilot Study on the Effect of Cannabis Oil in Untreatable Liver Cancer Patients
University Medical Center Groningen
NCT06512467 NOT YET RECRUITING Donafenib Combine With Sintilimab and HAIC in Neoadjuvant of Resectable Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT04563338 RECRUITING An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)
University Health Network, Toronto
NCT05844046 RECRUITING Sequential or Up-front Triple Treatment With Durvalumab, Tremelimumab and Bevacizumab for Non-resectable Hepatocellular Carcinoma (HCC) Patients
Enrico De Toni
NCT06405061 RECRUITING Evaluation of Effectiveness and Safety of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT06498622 RECRUITING Adjuvant Treatment of Patients With High Risk of Recurrent Hepatocellular Carcinoma With Donafenib in Combination With Envafolimab
Anhui Provincial Hospital
NCT05389527 ACTIVE NOT RECRUITING Pembrolizumab and Lenvatinib for Resectable Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
NCT06138769 ACTIVE NOT RECRUITING Lenvatinib After Progression on Atezolizumab-bevacizumab in Hepatocellular Carcinoma
Asan Medical Center
NCT06090656 RECRUITING Bevacizumab in Combination With Sintilimab Versus Transcatheter Arterial Chemoembolization for the Treatment of Intermediate Stage Hepatocellular Carcinoma (Beyond Up-To-Seven Criteria)
Sun Yat-sen University
NCT06482008 NOT YET RECRUITING HAIC Combined With Adebrelimab Plus Apatinib as the First-line Treatment for HCC in BCLC Stage C: An Open-label, Single-arm, Phase II Study
Sun Yat-sen University
NCT06482801 RECRUITING Checkpoint Inhibitor Combinations Therapy as First Line for HCC Via IT
Second Affiliated Hospital of Guangzhou Medical University
NCT06475287 NOT YET RECRUITING HAIC Combined With TQB2450 and Anlotinib in Second-line Treatment of Advanced Hepatocellular Carcinoma
Fudan University
NCT05187338 RECRUITING Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT04803318 RECRUITING Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT05444088 RECRUITING Study of SHR-8068 Combined With Adebrelimab and Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06441019 NOT YET RECRUITING Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma
Fudan University
NCT04224636 RECRUITING Atezolizumab/Bevacizumab Followed by On-demand TACE or Initial Synchronous Treatment With TACE and Atezolizumab/Bevacizumab
Ludwig-Maximilians - University of Munich
NCT05269381 RECRUITING Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Mayo Clinic
NCT05304234 RECRUITING Liver Cancer Disparities in American Indian and Alaska Native Persons
University of Washington
NCT06413017 RECRUITING Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure
Tianjin Medical University Cancer Institute and Hospital
NCT06409637 NOT YET RECRUITING FOLFOX Plus Lenvatinib Adjuvant Therapy for Hepatocellular Carcinoma Post-Liver Transplantation
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06408623 NOT YET RECRUITING Chidamide Combined With Sintilimab and Bevacizumab for the First-line Treatment of Advanced Liver Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06406634 RECRUITING Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma
Hunan Cancer Hospital
NCT06397222 RECRUITING Sintilimab Plus Bevacizumab and SIRT for Intermediate-advanced HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT06389422 RECRUITING Phase II Study of Moderate-dose Hypofractionated RT Combined With Pembrolizumab for HCC With Diffuse Tumor Thrombosis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06360042 RECRUITING Anti-PD-1/PD-L1 Combined With Anti-angiogenic Agents as First-line Treatment for Unresectable HCC
Peking University Cancer Hospital & Institute
NCT06375486 RECRUITING Ivonescimab Combined With HAIC for the Treatment of Unresectable Hepatocellular Carcinoma(uHCC).
Tianjin Medical University Cancer Institute and Hospital
NCT06375317 NOT YET RECRUITING HAIC Combined With PD-L1 Plus Regorafenib in the Treatment of Advanced Hepatocellular Carcinoma After Immunotherapy Failure
Yehua Shen
NCT06370065 RECRUITING Serplulimab Combined With Bevacizumab Biosimilar and HAIC in Advanced Hepatocellular Carcinoma (HCC) Patients
Tianjin Medical University Cancer Institute and Hospital
NCT06363825 RECRUITING A Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma
Fujian Medical University
NCT06364007 RECRUITING HAIC Combined With Durvalumab and Tremelimumab and Lenvatinib in uHCC
Sulai Liu
NCT05652920 RECRUITING Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC
OriCell Therapeutics Co., Ltd.
NCT06261125 RECRUITING Combination of SBRT, PD-L1 Inhibitor, and Lenvatinib in Hepatocellular Carcinoma (HSBRT2401)
Mian XI
NCT06253598 NOT YET RECRUITING Efficacy and Safety of Intratumoral Injection of Recombinant Human Adenovirus Type 5 Combined With Tislelizumab and Lenvatinib in the Treatment of Advanced Hepatocellular Carcinoma
The First Affiliated Hospital of Bengbu Medical University
NCT05970666 RECRUITING Single Arm, Prospective, Multicenter Clinical Study of TACE With Adebrelimab and Bevacizumab for Unresectable Hepatocellular Carcinoma
The First Affiliated Hospital of Xiamen University
NCT05924997 RECRUITING Adebrelimab, Camrelizumab Plus Apatinib as First-line Therapy in Patients With Advanced Hepatocellular Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT03474822 RECRUITING Plasmodium Immunotherapy for Breast and Liver Cancers
CAS Lamvac Biotech Co., Ltd.
NCT06244225 RECRUITING HAIC (Hepatic Artery Infusion Chemotherapy,HAIC)Plus Sintilimab and Donafenib in the First-line Treatment of Unresectable Hepatocellular Carcinoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT06205472 RECRUITING Phase II Study of Adjuvant SIB Radiotherapy Following Narrow-Margin Hepatectomy in Patients With HCC.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06196775 NOT YET RECRUITING A Study of Cadonilimab Combined With AK112 as Second-line Therapy in Patients With Advanced Hepatocellular Carcinoma
Harbin Medical University
NCT06193733 NOT YET RECRUITING Dendritic Cell Vaccination to Prevent Hepatocellular Carcinoma Recurrence After Liver Resection-phase II Clinical Trial
Chang Gung Memorial Hospital
NCT06143579 NOT YET RECRUITING A Study of HAIC Combined With Lenvatinib and Envolizumab in Potentially Resectable Hepatocellular Carcinoma
Sun Yat-sen University
NCT06124001 NOT YET RECRUITING Clinical Study of VG161 Combined With Camrelizumab in Patients With Advanced Primary Hepatocellular Carcinoma
CNBG-Virogin Biotech (Shanghai) Ltd.
NCT06111326 NOT YET RECRUITING BC3402 in Combination With Durvalumab in Patients With Advanced Hepatocellular Carcinoma
Biocity Biopharmaceutics Co., Ltd.
NCT05992584 RECRUITING Lenvatinib, Sintilimab Plus SIRT for Unresectable HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT06034977 RECRUITING Phase 2 Study of ADI-PEG 20 Plus Lenvatinib Treatment in Subjects With Unresectable Hepatocellular Carcinoma
Chang Gung Memorial Hospital
NCT04988945 RECRUITING TACE and SBRT Followed by Double Immunotherapy for Downstaging Hepatocellular Carcinoma
The University of Hong Kong
NCT05975463 NOT YET RECRUITING Hepatic Artery Infusion of Adebrelimab Combined With Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma With Failure of Systemic Therapy Combined With Interventional Therapy
HuiKai Li
NCT05954897 RECRUITING Lenvatinib, Tislelizumab Combined With RALOX Regimen HAIC in Advanced Hepatocellular Carcinoma
Guangdong Provincial People's Hospital
NCT05917431 RECRUITING Phase 2 Study of SBRT Plus Tislelizumab and Regorafenib in Unresectable or Oligometastatic HCC
Peking University Cancer Hospital & Institute
NCT05908916 NOT YET RECRUITING Atezolizumab and Bevacizumab With Combined Radiotherapy for Advanced Hepatocellular Carcinoma
Yonsei University
NCT05897138 NOT YET RECRUITING A Study to Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses
Fujian Cancer Hospital
NCT05809869 RECRUITING Immunotherapy and Radioembolisation for Metastatic Hepatocellular Carcinoma
The University of Hong Kong
NCT05407519 RECRUITING A Study to Evaluate Tislelizumab Combined With Sitravatinib as Adjuvant Therapy in Participants With HCC at High Risk of Recurrence After Curative Resection
Anhui Provincial Hospital
NCT05286320 NOT YET RECRUITING Phase Ib/II Trial of Combining Pembrolizumab and Lenvatinib With SBRT for HCC Patients With Portal Vein Thrombosis.
National Taiwan University Hospital
NCT05171335 ENROLLING BY INVITATION Neoadjuvant Combination Therapy of Lenvatinib and TACE for Transplant-Eligible Large Hepatocellular Carcinoma Patients
The Methodist Hospital Research Institute
NCT03482102 RECRUITING Durvalumab (MEDI4736) and Tremelimumab and Radiation Therapy in Hepatocellular Carcinoma and Biliary Tract Cancer
Massachusetts General Hospital
NCT05507632 NOT YET RECRUITING Donafenib Plus Sintilimab in Combination With TACE in Patients With Unresectable Hepatocellular Carcinoma
Nanfang Hospital, Southern Medical University
NCT05323201 RECRUITING Study Of B7H3 CAR-T Cells in Treating Advanced Liver Cancer
The Affiliated Hospital of Xuzhou Medical University
NCT03836352 ACTIVE NOT RECRUITING Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors
ImmunoVaccine Technologies, Inc. (IMV Inc.)
NCT03897543 RECRUITING ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma
Abivax S.A.
NCT05432492 COMPLETED A Study of AK112 in Patients With Unresectable Hepatocellular Carcinoma (HCC)
Akeso
NCT04785287 TERMINATED Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies
M.D. Anderson Cancer Center
NCT04945720 COMPLETED Hepatic Artery Infusion Chemotherapy (HAIC) Plus Durvalumab for Advanced Hepatocellular Carcinoma
Sun Yat-sen University
NCT03785210 TERMINATED Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers
National Cancer Institute (NCI)
NCT06608940 WITHDRAWN BC3402 w/ Tremelimumab + Durvalumab (STRIDE) in Hepatocellular Carcinoma
Case Comprehensive Cancer Center
NCT06851104 TERMINATED A Prospective Study of Cadonilimab in Hepatocellular Carcinoma After Radical Surgery With High Risk of Recurrence
Guangxi Medical University
NCT03463876 COMPLETED A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib in Patients With Advanced HCC(RESCUE)
Jiangsu HengRui Medicine Co., Ltd.
NCT03211416 COMPLETED Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer
Roswell Park Cancer Institute
NCT05176223 COMPLETED 68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer
Mayo Clinic
NCT03092895 COMPLETED A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC
Jiangsu HengRui Medicine Co., Ltd.
NCT05166239 COMPLETED HAIC Combine With Lenvatinib and PD-1 Inhibitors for Advanced HCC With PVTT
Peking University
NCT05641896 COMPLETED Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers
SOFIE
NCT05349331 COMPLETED Watch and Wait and Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma
Sun Yat-sen University
NCT05337137 COMPLETED A Study of Nivolumab and Relatlimab in Combination With Bevacizumab in Advanced Liver Cancer
Bristol-Myers Squibb
NCT04260802 TERMINATED A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
Ocellaris Pharma, Inc.
NCT04567615 COMPLETED A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors
Bristol-Myers Squibb
NCT03199274 COMPLETED Perflutren Protein-Type A Microspheres and Contrast-Enhanced Ultrasound in Improving Response to Radioembolization Therapy in Patients With Liver Cancer
Thomas Jefferson University
NCT05117957 COMPLETED Efficacy and Safety of Sorafenib in Previously Treated Advanced Hepatocellular Carcinoma: SOPT Study
Bo Hyun Kim
NCT04805788 TERMINATED Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer
Mayo Clinic
NCT05532319 COMPLETED HAIC Sequential TAE Combined With Lenvatinib and Tislelizumab in Unresectable HCC
Guangxi Medical University
NCT05908786 COMPLETED A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma
Hoffmann-La Roche
NCT04798781 COMPLETED Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma
Andrew Hendifar, MD
NCT04828486 COMPLETED Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer
Mayo Clinic
NCT06994299 WITHDRAWN A Pilot Trial of Preoperative Irradiation With the STRIDE (Single Dose of Tremelimumab With Ongoing Durvalumab) Regimen (PRISM) for Resectable/Advanced Hepatocellular Carcinoma
Weill Medical College of Cornell University
NCT05256381 TERMINATED A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors
SOTIO Biotech AG
NCT05367687 COMPLETED A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) Versus Camrelizumab as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation
Jiangsu HengRui Medicine Co., Ltd.
NCT05622071 COMPLETED Testing Immunotherapy for Patients With Liver Cancer and Moderately Altered Liver Functions
UNICANCER
NCT05359861 COMPLETED Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma
Coherus Oncology, Inc.
NCT04762888 COMPLETED 68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer
Mayo Clinic
NCT05091346 COMPLETED A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumors
Eisai Inc.
NCT05220722 TERMINATED Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors
TriSalus Life Sciences, Inc.
NCT05620771 SUSPENDED Therasphere® and Systemic Therapy for Patients With Hepatocellular Carcinoma That is High-risk
Northwestern University
NCT04050462 TERMINATED Nivolumab Combined With BMS-986253 in HCC Patients
NYU Langone Health
NCT05199285 TERMINATED A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab
Academic and Community Cancer Research United
NCT03044587 COMPLETED Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer
AIO-Studien-gGmbH
NCT05104567 COMPLETED A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)
Sanofi
NCT05537402 TERMINATED LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC
University of Texas Southwestern Medical Center
NCT04264260 COMPLETED Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment
Kaohsiung Medical University Chung-Ho Memorial Hospital
NCT04997850 COMPLETED The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma
Xinrui Zhu,MD
NCT05009979 TERMINATED 18F-DCFPyL PET/CT in Hepatocellular Carcinoma
National Cancer Institute (NCI)
NCT03638141 COMPLETED CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05007106 COMPLETED MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)
Merck Sharp & Dohme LLC
NCT04791176 COMPLETED Phase II Study of Concurrent Lenvatinib and Radiotherapy for Advanced HCC
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT04740307 COMPLETED Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)
Merck Sharp & Dohme LLC
NCT05797870 SUSPENDED Selective Internal Radiation Therapy and 188Re-SSS Lipiodol Treatment for Liver Cancer (Lip-Re2)
Center Eugene Marquis
NCT03316872 TERMINATED Study of Pembrolizumab and Radiotherapy in Liver Cancer
University Health Network, Toronto
NCT05101629 COMPLETED Pembrolizumab and Lenvatinib in Patients With Advanced HCC Who Are Refractory to Atezolizumab and Bevacizumab/ IO-based Therapy
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT02940496 COMPLETED Pembrolizumab (MK-3475) in Hepatocellular Carcinoma
M.D. Anderson Cancer Center
NCT05563272 TERMINATED 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT02185768 COMPLETED Chemoembolisation of Hepatocellular Carcinomas Not Subject to Interventive Care by Idarubicin-loaded Beads - IDASPHERE II
Federation Francophone de Cancerologie Digestive
NCT03781934 COMPLETED A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations
Medivir
NCT05630937 TERMINATED Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy
Nerviano Medical Sciences
NCT05603572 SUSPENDED KAT-101 in Subjects With Hepatocellular Carcinoma (HCC)
Primocure Pharma
NCT06361758 WITHDRAWN Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCC
Shanghai Zhongshan Hospital
NCT04611165 COMPLETED Concurrent Nivolumab and External Beam Radiation Therapy for Patients With Advanced HCC
National Cancer Center, Korea
NCT04696055 COMPLETED Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors
Bayer
NCT05750030 COMPLETED FMT in IT-refractory HCC - FAB-HCC Pilot Study
Medical University of Vienna
NCT02939807 WITHDRAWN A Phase II Study of ABC294640 as Monotherapy in Patients With Advanced Hepatocellular Carcinoma
Medical University of South Carolina
NCT05448677 TERMINATED Ezurpimtrostat Autophagy Inhibitor in Association With Atezolizumab-Bevacizumab in First Line Treatment of Unresectable Hepatocellular Carcinoma
University Hospital, Grenoble
NCT02234986 COMPLETED A Multi-center, Open-label Study of Oral ENMD-2076 for the Treatment of Patients With Advanced Fibrolamellar Carcinoma
CASI Pharmaceuticals, Inc.
NCT04000737 COMPLETED YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC)
Yiviva Inc.
NCT03829501 TERMINATED A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies
Kymab Limited
NCT04316182 COMPLETED Cabozantinib in Patients With Hepatocellular Carcinoma (ACTION)
Fundacion Clinic per a la Recerca Biomédica
NCT04976660 WITHDRAWN TT-4 As a Single Agent in Subjects with Advanced Selected Solid Tumors
Tarus Therapeutics, Inc.
NCT04629339 TERMINATED Study of INCB086550 in Select Solid Tumors
Incyte Corporation
NCT04172506 COMPLETED A Study to Evaluate the Efficacy and Safety of Anti-PD-1 Antibody AK105 in Patients With Selected Advanced Solid Tumors
Akeso
NCT05137899 TERMINATED Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy
Ontario Clinical Oncology Group (OCOG)
NCT05770882 TERMINATED Chidamide + Regorafenib in Hepatocellular Carcinoma (HCC)
Great Novel Therapeutics Biotech & Medicals Corporation
NCT04401800 COMPLETED Preliminary Antitumor Activity, Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma
BeiGene
NCT04710641 COMPLETED Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone
Mina Alpha Limited
NCT03058289 COMPLETED A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Intensity Therapeutics, Inc.
NCT04297280 COMPLETED TACE Combined with Anti-PD-1 Antibody in Patients with Advanced Hepatocellular Carcinoma
Fudan University
NCT06848556 TERMINATED Evaluate the Effect of Tirazamine on Primary Liver Cancer.
Zhejiang Raygene Pharmaceuticals Co., Ltd
NCT04948697 COMPLETED A Study Investigating the Efficacy and Safety of Ociperlimab and Tislelizumab and BAT1706 Combinations in Patients With Advanced HCC
BeiGene
NCT03190174 COMPLETED Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
Sarcoma Oncology Research Center, LLC
NCT05162352 COMPLETED Donafenib Plus Sintilimab for Advanced HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT03439891 COMPLETED Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer
Robin Kate Kelley
NCT02421185 COMPLETED Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 (Erdafitinib) in Participants With Advanced Hepatocellular Carcinoma
Janssen Research & Development, LLC
NCT05497453 TERMINATED A Phase 1/2 Study to Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene
Omega Therapeutics
NCT04511455 COMPLETED Cabozantinib for Patients with Hepatocellular Carcinoma (HCC) Refractory to First Line Treatment
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT04522908 COMPLETED Dose Escalation Study of Cabozantinib for Advanced HCC Patients With Preserved Liver Function
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT04767906 COMPLETED Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors
University of Leipzig
NCT05776875 TERMINATED Atezolizumab and Bevacizumab in Combination With TACE for Patients With BCLC B HCC
Yale University
NCT05653427 TERMINATED A Study of Amivantamab Monotherapy in Participants With Previously Treated Advanced Hepatocellular Carcinoma
Janssen Research & Development, LLC
NCT05302921 COMPLETED Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
Children's National Research Institute
NCT02528643 COMPLETED A Study to Assess the Efficacy and Safety of Enzalutamide in Subjects With Advanced Hepatocellular Carcinoma
Astellas Pharma Global Development, Inc.
NCT03009461 COMPLETED Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC with Major Portal Vein Tumor Thrombosis
Peking University
NCT04701060 COMPLETED Camrelizumab Combined With Apatinib for Perioperative Treatment of Resectable Primary Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital
NCT03145558 TERMINATED TATE Versus TACE in Intermediate Stage HCC
Teclison Ltd.
NCT03606590 COMPLETED Effect of Tumor Treating Fields (TTFields, 150kHz) Concomitant with Sorafenib for Advanced Hepatocellular Carcinoma (HCC) (HEPANOVA)
NovoCure Ltd.
NCT05003700 COMPLETED Hepatic Arterial Infusion Combined With Lenvatinib and Camrelizumab for Unresectable Hepatocellular Carcinoma
Nanfang Hospital, Southern Medical University
NCT04954794 COMPLETED TACE Combined with Sintilimab Plus Bevacizumab Biosimilar in Patients with Advanced Hepatocellular Carcinoma (TASK-02)
Fudan University
NCT03419897 COMPLETED Study of BGB-A317 in Participants With Previously Treated Unresectable HCC
BeiGene
NCT03941873 COMPLETED A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer
BeiGene
NCT04011033 COMPLETED Study of Adoptive Transfer of iNKT Cells Combined With TAE/TACE to Treat Unresectable HCC
Beijing YouAn Hospital
NCT04327700 TERMINATED Study Of Intrabucally Administered Electromagnetic Fields and Regorafenib
Wake Forest University Health Sciences
NCT04542837 COMPLETED The Study of KN046 in Combination With Lenvatinib in Advanced Hepatocellular Carcinoma
Peking University Cancer Hospital & Institute
NCT02702414 COMPLETED Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Advanced Hepatocellular Carcinoma (MK-3475-224/KEYNOTE-224)
Merck Sharp & Dohme LLC
NCT04170556 COMPLETED Regorafenib Followed by Nivolumab in Patients With Hepatocellular Carcinoma (GOING)
Fundacion Clinic per a la Recerca Biomédica
NCT02431676 COMPLETED Survivorship Promotion In Reducing IGF-1 Trial
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06006286 WITHDRAWN A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma
M.D. Anderson Cancer Center
NCT02509507 COMPLETED Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611
Amgen
NCT04497038 TERMINATED Cabozantinib in Patients With Advanced Hepatocellular Carcinoma With Child Pugh Class B Cirrhosis After First-Line Therapy
University of Michigan Rogel Cancer Center
NCT04931420 WITHDRAWN Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
University of Chicago
NCT03630640 COMPLETED Neoadjuvant and Adjuvant Nivolumab in HCC Patients Treated by Electroporation
Assistance Publique - Hôpitaux de Paris
NCT04212221 TERMINATED MGD013 Monotherapy and Combination With Brivanib Dose Escalation and Expansion Study in Advanced Liver Cancer Patients
Zai Lab (Shanghai) Co., Ltd.
NCT03753659 COMPLETED IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC)
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT02314052 TERMINATED Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
NCT03510871 COMPLETED Nivolumab Plus Ipilimumab as Neoadjuvant Therapy for Hepatocellular Carcinoma (HCC)
National Health Research Institutes, Taiwan
NCT04518852 COMPLETED TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC
Sichuan Cancer Hospital and Research Institute
NCT06232759 COMPLETED TACE Combined With Tyrosine Kinase Inhibitors and Tislelizumab in Unresectable Hepatocellular Carcinoma
Guangxi Medical University
NCT04541173 TERMINATED Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC)
Aiwu Ruth He, MD
NCT04172571 COMPLETED A Study of the Combination of Anti-PD-1 AK105 and Anlotinib in First-line Hepatocellular Carcinoma (HCC)
Akeso
NCT04842565 COMPLETED cTACE Plus Sintilimab for Unresectable Intermediate-stage HCC With Beyond Up-to-seven Criteria
Fudan University
NCT03817736 COMPLETED Sequential TACE and SBRT Followed by ImmunoTherapy for Downstaging HCC for Hepatectomy
The University of Hong Kong
NCT05040438 COMPLETED Natural Killer (NK) Cell Therapy in Locally Advanced HCC
Vaxcell Bio, Co., Ltd.
NCT02705105 COMPLETED Study of Mogamulizumab + Nivolumab in Subjects w/Locally Advanced or Metastatic Solid Tumors
Kyowa Kirin, Inc.
NCT04444167 COMPLETED A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Plus Lenvatinib in First-line Advanced Hepatocellular Carcinoma
Akeso
NCT04728321 COMPLETED A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Alone or in Combination With Lenvatinib in Advanced Hepatocellular Carcinoma
Akeso
NCT02989922 COMPLETED A Study to Evaluate SHR-1210 in Subjects With Advanced HCC
Jiangsu HengRui Medicine Co., Ltd.
NCT03893695 COMPLETED Combination of GT90001 and Nivolumab in Patients With Metastatic Hepatocellular Carcinoma(HCC)
Suzhou Kintor Pharmaceutical Inc,
NCT03422679 TERMINATED Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
Cellestia Biotech AG
NCT03535259 COMPLETED Phase II Study of Concurrent Sorafenib and Intensity-modulated Radiotherapy (IMRT) for Advanced Hepatocellular Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05363605 TERMINATED A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours
Fusion Pharmaceuticals Inc.
NCT03867370 TERMINATED Toripalimab in Combination With Lenvatinib as Neoadjuvant Therapy in Resectable Hepatocellular Carcinoma
Shanghai Junshi Bioscience Co., Ltd.
NCT02232633 COMPLETED A Study of BBI503 in Adult Patients With Advanced Hepatobiliary Cancer
Sumitomo Pharma America, Inc.
NCT04942665 COMPLETED Low Dose ICG for Biliary Tract and Tumor Imaging
University of Florida
NCT03695250 TERMINATED BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer
Edward Kim
NCT03602079 COMPLETED Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Klus Pharma Inc.
NCT03572582 COMPLETED Transarterial Chemoembolization in Combination With Nivolumab Performed for Intermediate Stage Hepatocellular Carcinoma
AIO-Studien-gGmbH
NCT05109052 WITHDRAWN Trial of PXS-5505 Combined With First Line Atezolizumab Plus Bevacizumab For Treating Patients With Unresectable Hepatocellular Carcinoma
University of Rochester
NCT03970616 TERMINATED A Study of Tivozanib in Combination With Durvalumab in Subjects With Advanced Hepatocellular Carcinoma
AVEO Pharmaceuticals, Inc.
NCT03722498 WITHDRAWN Phase Ⅱ Study of HAIC of FOLFOX vs. Sorafenib in HCC Refractory to TACE
Sun Yat-sen University
NCT03591965 TERMINATED Dual TORC1/TORC2 Inhibitor ATG-008 (CC-223) in HBV Positive Advanced Hepatocellular Carcinoma (HCC) Subjects
Antengene Therapeutics Limited
NCT03222076 COMPLETED Nivolumab With or Without Ipilimumab in Treating Patients With Resectable Liver Cancer
M.D. Anderson Cancer Center
NCT02795429 COMPLETED Phase Ib/II Study of INC280 + PDR001 or PDR001 Single Agent in Advanced HCC
Novartis Pharmaceuticals
NCT02856815 COMPLETED Safety and Efficacy of "Immuncell-LC" in TACE Therapy
GC Cell Corporation
NCT05213221 COMPLETED Study on Therapeutic Effect of Combination of Envafolimab, Lenavatinib and TACE in Advanced HCC Patients
Zhejiang University
NCT04044313 COMPLETED HAIC Plus Lenvatinib and Toripalimab for Advanced HCC
Shi Ming
NCT05886257 WITHDRAWN Candonilimab Plus Bevacizumab for Patients With Advanced HCC Who Progressed on A+T
Shi Ming
NCT05039736 WITHDRAWN A Phase II Study to Evaluate the Effects of Sequential Therapy With the Anti c-MET/VEGFR Tyrosine Kinase Inhibitor (TKI), Cabozantinib, Followed by an Anti-PD-1 Antibody (Nivolumab) in Patients With Advanced HCC Who Progressed on First-line Therapy
M.D. Anderson Cancer Center
NCT03841201 COMPLETED Immunotherapy With Nivolumab in Combination With Lenvatinib for Advanced Stage Hepatocellular Carcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT05249569 TERMINATED Study of Bavituximab, Axitinib, and Avelumab in Advanced Hepatocellular Carcinoma
University of Texas Southwestern Medical Center
NCT03586973 COMPLETED A Phase 2 Study of Cabozantinib in Japanese Participants With Advanced Hepatocellular Carcinoma
Takeda
NCT04442581 TERMINATED Cabozantinib and Pembrolizumab for the First-Line Treatment of Advanced Liver Cancer
University of Washington
NCT02821754 COMPLETED A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
National Cancer Institute (NCI)
NCT05157451 WITHDRAWN Y-90 Versus SBRT for Inoperable HCC
OHSU Knight Cancer Institute
NCT05212922 WITHDRAWN A Study to Evaluate YH001 in Combination With Toripalimab in Subjects With Advanced NSCLC and HCC
Eucure (Beijing) Biopharma Co., Ltd
NCT04124991 COMPLETED Safety and Efficacy Study of Radioembolization in Combination With Durvalumab in Locally Advanced and Unresectable HCC
Seoul National University Hospital
NCT04965714 WITHDRAWN Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver Cancer
M.D. Anderson Cancer Center
NCT04194801 COMPLETED A Phase Ib/II Study of Fisogatinib(BLU-554) in Subjects With Hepatocellular Carcinoma
CStone Pharmaceuticals
NCT05471674 COMPLETED Neoadjuvant Anti-PD1 in HCC
Dr Tan-to CHEUNG
NCT05628545 WITHDRAWN Adoptive Treatment of Advanced Hepatocellular Carcinoma With Allogeneic γδ-T Cells
Guangdong GD Kongming Biotech LLC
NCT03648073 COMPLETED [68Ga]DOTATATE-PET/MRI in Hepatocellular Carcinoma
University of Alabama at Birmingham
NCT03582618 TERMINATED CVM-1118 and Sorafenib Combination in Subjects With Advanced Hepatocellular Carcinoma
TaiRx, Inc.
NCT04123340 COMPLETED Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation
Leiden University Medical Center
NCT02794805 COMPLETED Determination of HCC With Octanoate Breath Test vs. MRI Diagnosis
Meridian Bioscience, Inc.
NCT05327738 WITHDRAWN Yttrium Y 90 Glass Microspheres, Atezolizumab, and Cabozantinib for the Treatment of Unresectable or Locally Advanced Hepatocellular Carcinoma
OHSU Knight Cancer Institute
NCT03781960 TERMINATED Abemaciclib and Nivolumab for Subjects With Hepatocellular Carcinoma
Abramson Cancer Center at Penn Medicine
NCT04178642 WITHDRAWN The Impact on Hepatic Recurrence After Adjuvant Chemotherapy With Intraarterial Infusion of Idarubicin-Lipiodol
University Hospital, Montpellier
NCT04310709 COMPLETED Combination of Regorafenib and Nivolumab in Unresectable Hepatocellular Carcinoma
Asan Medical Center
NCT04599790 COMPLETED TACE Combined With Lenvatinib and Sintilimab for Advanced HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT03379844 COMPLETED HEPAR Primary: Holmium-166-radioembolization in Hepatocellular Carcinoma Patients
UMC Utrecht
NCT04601610 TERMINATED KN046 Combined With Ningatinib in the Treatment of Advanced Hepatocellular Carcinoma
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT04599777 COMPLETED TACE Combined With Sorafenib and Tislelizumab for Advanced HCC
Second Affiliated Hospital of Guangzhou Medical University
NCT03945799 TERMINATED A Multicenter Study of Anlotinib in Hepatocellular Carcinoma (HCC) Patients at High Risk of Post Surgery Recurrence
Zhejiang University
NCT05517239 COMPLETED Gemcitabine With Oxaliplatin (GEMOX) in Patients With Advanced Hepatocellular Carcinoma After Failure of Sorafenib Treatment
Yonsei University
NCT05502458 COMPLETED Effect of Propofol and Desflurane on Nucleic Acid of Liver Circulating Tumor
Zhejiang Cancer Hospital
NCT03163992 COMPLETED Pembrolizumab in Advanced Hepatocellular Carcinoma as Second-line Treatment After Failure of Sorafenib
Samsung Medical Center
NCT02575339 TERMINATED MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma
Kathy Miller
NCT03634683 WITHDRAWN A Study of LioCyx in Patient With Recurrent HBV-related HCC Post Liver Transplantation
Lion TCR Pte. Ltd.
NCT03655613 TERMINATED APL-501 or Nivolumab in Combination With APL-101 in Locally Advanced or Metastatic HCC and RCC
Apollomics (Australia) Pty. Ltd.
NCT03316222 TERMINATED Study of GNS561 in Patients With Liver Cancer
Genoscience Pharma
NCT03908255 WITHDRAWN Branched-chain Amino Acid Supplementation for Hepatocellular Carcinoma
Louisiana State University Health Sciences Center in New Orleans
NCT04653389 TERMINATED Perioperative Therapy for Hepatocellular Carcinoma
Zhejiang University
NCT04476329 TERMINATED Optimization for Regorafenib in HCC
SC Liver Research Consortium, LLC
NCT04105062 WITHDRAWN LS301 Uptake in Tumors of Patients Undergoing Liver, Pancreas, or Gastric Surgery
Washington University School of Medicine
NCT03111732 COMPLETED Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC)
National Cancer Institute (NCI)
NCT03071094 TERMINATED A Trial to Evaluate the Safety and Efficacy of the Combination of the Oncolytic Immunotherapy Pexa-Vec With the PD-1 Receptor Blocking Antibody Nivolumab in the First-line Treatment of Advanced Hepatocellular Carcinoma (HCC)
Transgene
NCT02973516 COMPLETED Proof of Concept Study Concerning Efficacy of P03277 MR Imaging in HCC Diagnosis
Guerbet
NCT03109886 COMPLETED Study of Milciclib in Patients With Unresectable/Metastatic Hepatocellular Carcinoma
Tiziana Life Sciences LTD
NCT02423343 COMPLETED A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, or Hepatocellular Carcinoma
Eli Lilly and Company
NCT04947371 WITHDRAWN Adjuvant Therapy With Anlotinib for HCC
Shanghai Zhongshan Hospital
NCT03245190 COMPLETED Study of Chiauranib in Patients With Advanced Hepatocellular Carcinoma
Chipscreen Biosciences, Ltd.
NCT02859324 COMPLETED A Safety and Efficacy Study of CC-122 in Combination With Nivolumab in Subjects With Unresectable Hepatocellular Carcinoma (HCC)
Celgene
NCT02721056 TERMINATED NBTXR3 Crystalline Nanoparticles and Stereotactic Body Radiation Therapy in the Treatment of Liver Cancers
Nanobiotix
NCT03608878 TERMINATED Adagloxad Simolenin/OBI-821 in Combination With TACE Therapy in HCC Patients With GALNT14-rs9679162-non-TT Genotype
Chang Gung Memorial Hospital
NCT03563170 WITHDRAWN QUILT-3.072: NANT Hepatocellular Carcinoma (HCC) Vaccine
ImmunityBio, Inc.
NCT03389126 COMPLETED Phase II Study of Avelumab in Patients With Advanced Hepatocellular Carcinoma After Prior Sorafenib Treatment
Seoul National University Hospital
NCT04526080 WITHDRAWN Intrabucally Administered Electromagnetic Fields Versus Placebo as Third-line Therapy For Patients With Advanced Hepatocellular Carcinoma
Wake Forest University Health Sciences
NCT03303469 TERMINATED Hypoxic Changes in Hepatocellular Carcinoma (HCC) Following Trans Arterial Chemo Embolization and Stereotactic Radiation: Fluorine18 (18F) Fluoromisonidazole (FMISO) Imaging
University of Alabama at Birmingham
NCT02129322 WITHDRAWN Effect of Adjuvant Therapy by Sorafenib, Oxaliplatin and S-1
Zhejiang University
NCT03008512 TERMINATED A Phase II Study of Weekly Genexol-PM in Patients With Hepatocelluar Carcinoma After Failure of Sorafenib
Gachon University Gil Medical Center
NCT02524119 TERMINATED LEE001 and Chemoembolization In Patients With Advanced Hepatocellular Carcinoma
University of Texas Southwestern Medical Center
NCT03219372 TERMINATED Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence
Cedars-Sinai Medical Center
NCT02658019 COMPLETED Pembrolizumab (Keytruda) in Advanced Hepatocellular Carcinoma
Lynn Feun, MD
NCT03380130 COMPLETED A Study of the Safety and Antitumoral Efficacy of Nivolumab After SIRT for the Treatment of Patients With HCC
Clinica Universidad de Navarra, Universidad de Navarra
NCT03086564 COMPLETED A Basic-clinical Translational Research in Hepatitis B Virus (HBV)-Specific Antigen Peptides and HepG2 Cell Lysate Co-activated Dendritic Cells Combined With Transarterial Chemoembolization (TACE) in HBV-related HCC Treatment (BTRHBVAPHCLCDCCTCHBVHCCT)
Yuehua Huang
NCT03484962 WITHDRAWN Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Liver Cancer
Fuda Cancer Hospital, Guangzhou
NCT02560779 COMPLETED Trial of TRC105 and Sorafenib in Patients With HCC
Tracon Pharmaceuticals Inc.
NCT02723942 WITHDRAWN CAR-T Cell Immunotherapy for HCC Targeting GPC3
Fuda Cancer Hospital, Guangzhou
NCT03183219 COMPLETED Safety and Efficiency of γδ T Cell Against Liver Cancer
Fuda Cancer Hospital, Guangzhou
NCT03575806 COMPLETED Combine TACE and Autologous Tcm Immunotherapy Versus TACE Alone for HCC With MVI After Radical Resection
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT02716766 COMPLETED Study of SECOX Versus Sorafenib as First-Line Treatment in Patients With Advanced Hepatocellular Carcinoma (HCC)
The University of Hong Kong
NCT03578874 COMPLETED SECOX as Neoadjuvant Therapy in Patients With Locally Advanced HCC
The University of Hong Kong
NCT04025567 WITHDRAWN Vancomycin in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLC) Oral
National Cancer Institute (NCI)
NCT02580253 WITHDRAWN Adjuvant Chemotherapy Based on the Adenosine Triphosphate Tumor Chemosensitivity Assay for Hepatocellular Carcinoma After Liver Transplantation
Zhejiang University
NCT03203005 COMPLETED IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients
National Cancer Institute, Naples
NCT02409524 COMPLETED An Individualized Anti-Cancer Vaccine in Advanced Hepatocellular Carcinoma Subjects
Mirror Biologics, Inc.
NCT02289300 WITHDRAWN A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer Patients
A2 Healthcare Taiwan Corporation
NCT02541370 COMPLETED Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
Chinese PLA General Hospital
NCT03433703 TERMINATED Trial to Evaluate Safety and Efficacy of Treatment of Physician Choice (TPC) Following First-Line Treatment of Lenvatinib in Subjects With Unresectable Hepatocellular Carcinoma (uHCC)
Eisai Inc.
NCT02854839 COMPLETED A Study of MG4101 (Allogeneic Natural Killer Cell) for Intermediate-stage of Hepatocellular Carcinoma
GC Cell Corporation
NCT02946138 WITHDRAWN Phase II Trial of Carbon-ion Radiotherapy Combined With GM-CSF for the Treatment of Hepatocellular Carcinoma
Shanghai Proton and Heavy Ion Center
NCT03516071 COMPLETED A Phase 2 Study of Brivanib in Chinese Patients With Previously Treated Advanced HCC
Zai Lab (Shanghai) Co., Ltd.
NCT03939975 COMPLETED Anti-PD-1therapy Combined With Thermal Ablation for Advanced HCC
Sun Yat-sen University
NCT03318562 TERMINATED A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC
Effector Therapeutics
NCT03919383 WITHDRAWN Phase II of Lenvatinib Plus Toripalimab for Advanced HCC
Sun Yat-sen University
NCT03775707 WITHDRAWN Lenvatinib Plus PD-1 Antibody for Intermediate-stage HCC Beyond Up-to-seven Criteria
Shi Ming
NCT03803254 WITHDRAWN HAIC Plus Lenvatinib and PD-1 Antibody Versus HAIC Plus Lenvatinib for Advanced HCC
Sun Yat-sen University
NCT03780634 WITHDRAWN HAIC Plus PD-1 Antibody vs HAIC Plus Sorafenib for Advanced HCC
Sun Yat-sen University
NCT03782831 WITHDRAWN TACE Plus PD-1 Antibody vs TACE Alone for Unresectable HCC
Sun Yat-sen University
NCT02471313 COMPLETED Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization
National Institutes of Health Clinical Center (CC)
NCT03746249 WITHDRAWN Phase II of Lenvatinib Plus PD-1 Antibody for Advanced HCC
Sun Yat-sen University
NCT02950025 TERMINATED Daily Online Adaptation Versus Localization for MRI-Guided SBRT for Unresectable Primary or Oligometastatic Abdominal Malignancies
Washington University School of Medicine
NCT02981498 COMPLETED Phase II Trial of Sorafenib Combined With Concurrent HAIC for Hepatocellular Carcinoma
Sun Yat-sen University
NCT02828124 TERMINATED A Study of the Safety and Tolerability of BMS-986183 in Patients With Liver Cancer
Bristol-Myers Squibb
NCT03035006 TERMINATED Lipotecan Based Concurrent Chemoradiotherapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis
Taiwan Liposome Company
NCT02702960 WITHDRAWN Sequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow Transplantation for Hepatocellular Carcinoma (HCC)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02908165 WITHDRAWN Randomized Phase II Trial of Chemoembolization and Sorafenib
Yale University
NCT02549755 TERMINATED 11C-acetate for Treatment Response After Radiotherapy for HCC
Justin Sims
NCT01171482 TERMINATED Comparison Study of Sorafenib and 5-fluorouracil/Mitomycin for Metastatic Hepatocellular Carcinoma
Seoul National University Hospital
NCT02997956 WITHDRAWN Study of Tocilizumab in Patients With Hepatocellular Carcinoma (HCC) Undergoing Transarterial Chemoembolization (TACE)
University of Michigan Rogel Cancer Center
NCT02819869 TERMINATED The Combination Effect of Statin Plus Metformin on Relapse-free
Taipei Medical University WanFang Hospital
NCT02261844 WITHDRAWN Resveratrol and Human Hepatocyte Function in Cancer
University of Louisville
NCT03048123 COMPLETED HAIC Versus TACE for Large and Unresectable Hepatocellular Carcinoma Staged BCLC A/B
Sun Yat-sen University
NCT01964235 WITHDRAWN Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular Carcinoma
Novartis Pharmaceuticals
NCT02545556 COMPLETED Liver Cancer HepaSphere Combined With Cryosurgery
Fuda Cancer Hospital, Guangzhou
NCT02425735 COMPLETED Safety and Efficiency of γδ T Cell Against Hepatocellular Liver Cancer
Fuda Cancer Hospital, Guangzhou
NCT01953406 WITHDRAWN The Efficacy of 5-fluorouracil/Mitomycin for the Patients With Pulmonary Metastasis of Hepatocellular Carcinoma
Seoul National University Hospital
NCT02447263 COMPLETED HepaSphere Interventional Therapy Using Digital Subtraction Angiography(DSA) for Liver Cancer
Fuda Cancer Hospital, Guangzhou
NCT02449109 COMPLETED Nano Drug Interventional Therapy Using Digital Subtraction Angiography(DSA) for Liver Carcinoma
Fuda Cancer Hospital, Guangzhou