TheraRadar

Pharma Intelligence, Simplified

Landscape → Infectious Disease

Malaria

336 clinical trials

69 active
/
336 total (since 2015)
23
Phase 1 Active
140 total
22
Phase 2 Active
108 total
14
Phase 3 Active
64 total
18
Phase 4 Active
64 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Sanaria Inc. 3 13 1
GSK 2 10 0
Novartis 1 11 2
Serum Institute of India Pvt. Ltd. 1 1 0
BioNTech SE 1 1 0
Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd 1 0 1
Zydus Lifesciences Limited 1 1 0
Eisai Inc. 1 0 0
NCT04704830 ACTIVE NOT RECRUITING
R21/Matrix-M in African Children Against Clinical Malaria
University of Oxford n=4,800
NCT04009343 ACTIVE NOT RECRUITING
Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials
Johns Hopkins Bloomberg School of Public Health n=182
NCT06962319 RECRUITING
Safety of Antimalarials in the FIRst trimEster
Liverpool School of Tropical Medicine n=1,510
NCT05951595 RECRUITING
A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines
University of Oxford n=1,680
NCT05690841 RECRUITING
FocaL Mass Drug Administration for Vivax Malaria Elimination
University of California, San Francisco n=7,530
NCT06923592 RECRUITING
Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar
London School of Hygiene and Tropical Medicine n=19,200
NCT06666491 RECRUITING
An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older
GlaxoSmithKline n=300
NCT07082205 RECRUITING
Monoclonal Antibodies in Children With Severe Anaemia or Severe Malaria to Prevent Malaria After Hospital Discharge
Liverpool School of Tropical Medicine n=398
NCT06148792 RECRUITING
A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria
Menzies School of Health Research n=1,090
NCT05426434 ACTIVE NOT RECRUITING
Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy
Menzies School of Health Research n=1,172
NCT06516042 ACTIVE NOT RECRUITING
Targeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia
PATH n=10,350
NCT04978272 ACTIVE NOT RECRUITING
Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
Grant Dorsey, M.D, Ph.D. n=924
NCT05764746 RECRUITING
Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial
Muhimbili University of Health and Allied Sciences n=384
NCT06578572 RECRUITING
Seasonal R21 Mass Vaccination for Malaria Elimination
London School of Hygiene and Tropical Medicine n=16,200
NCT05842954 COMPLETED
Efficacy, Safety and Tolerability of KLU156 in Adults and Children With Uncomplicated P. Falciparum Malaria
Novartis Pharmaceuticals n=1,720
NCT04300309 TERMINATED
Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria
Novartis Pharmaceuticals n=28
NCT03923725 COMPLETED
A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs.
University of Oxford n=2,583
NCT04336189 COMPLETED
Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda
Grant Dorsey, M.D, Ph.D. n=2,757
NCT03967054 COMPLETED
Repeat Ivermectin Mass Drug Administrations for MALaria Control II
Brian Foy n=4,124
NCT03300648 COMPLETED
Treating Brain Swelling in Pediatric Cerebral Malaria
Michigan State University n=57
NCT04966702 COMPLETED
Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)
Barcelona Institute for Global Health n=48,145
NCT06166498 COMPLETED
Parasite Clearance and Protection From Infection (PCPI) in Zambia
London School of Hygiene and Tropical Medicine n=600
NCT06173206 COMPLETED
Parasite Clearance and Protection from Infection (PCPI) in Cameroon
London School of Hygiene and Tropical Medicine n=902
NCT03640403 COMPLETED
Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania
National Institute for Medical Research, Tanzania n=1,555
NCT04411836 COMPLETED
Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine
Menzies School of Health Research n=960
NCT03074435 COMPLETED
Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire
Institut de Recherche pour le Developpement n=15,776
NCT03671109 COMPLETED
Improving Maternal heAlth by Reducing Malaria in African HIV Women
Barcelona Institute for Global Health n=666
NCT04319380 COMPLETED
Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study
London School of Hygiene and Tropical Medicine n=5,098
NCT06179732 COMPLETED
Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities
The Mentor Initiative n=2,400
NCT03939104 COMPLETED
A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia)
University of Oxford n=103
NCT04695197 COMPLETED
Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso
Liverpool School of Tropical Medicine n=143
NCT04844099 COMPLETED
Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia
Liverpool School of Tropical Medicine n=723
NCT04158713 COMPLETED
Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2)
Liverpool School of Tropical Medicine n=898
NCT03208907 COMPLETED
DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado n=419
NCT04189744 COMPLETED
The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract
London School of Hygiene and Tropical Medicine n=5,436
NCT05232227 WITHDRAWN
Primaquine Double Dose for Radical Cure of Plasmodium Vivax in Colombia
University of California, San Francisco
NCT04147546 COMPLETED
Additional Screening With Sensitives RDTs and Malaria
Institut de Recherche en Sciences de la Sante, Burkina Faso n=340
NCT04783051 COMPLETED
Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG)
University of Kinshasa n=250
NCT03355664 COMPLETED
Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam
University of Oxford n=310
NCT03208179 COMPLETED
Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa
Liverpool School of Tropical Medicine n=4,680
NCT03143218 COMPLETED
Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ)
London School of Hygiene and Tropical Medicine n=5,920
NCT05192265 COMPLETED
Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine
University of Ibadan n=172
NCT03576313 COMPLETED
Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination
London School of Hygiene and Tropical Medicine n=4,939
NCT03452475 COMPLETED
Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+Mefloquine Versus Artemether-lumefantrine in Kenyan Children
University of Oxford n=219
NCT02699099 COMPLETED
Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine.
GlaxoSmithKline n=699
NCT02315690 COMPLETED
Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland
University of California, San Francisco n=4,000
NCT03009526 COMPLETED
Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi
Kamuzu University of Health Sciences n=602
NCT02793622 COMPLETED
Prevention of Malaria in HIV-uninfected Pregnant Women and Infants
University of California, San Francisco n=782
NCT02802501 COMPLETED
Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria
GlaxoSmithKline n=150
NCT02610400 COMPLETED
Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia
University of California, San Francisco n=9,845
NCT02671175 COMPLETED
Post-discharge Malaria Chemoprevention(PMC) Study
Liverpool School of Tropical Medicine n=1,049
NCT03128515 COMPLETED
Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas
Indiana University n=187
NCT04049916 COMPLETED
Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission
London School of Hygiene and Tropical Medicine n=100
NCT03056391 COMPLETED
Effect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria
Menzies School of Health Research n=360
NCT02533336 TERMINATED
The Effectiveness of Non-Pyrethroid Insecticide-Treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania
National Institute for Medical Research, Tanzania n=4,917
NCT02509481 COMPLETED
Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study
Colorado State University n=2,712
NCT02216123 COMPLETED
Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria
GlaxoSmithKline n=251
NCT02453308 COMPLETED
A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC)
University of Oxford n=1,110
NCT02698748 COMPLETED
Evaluating the Role of Chloroquine for Malaria Elimination
Centro de Investigacao em Saude de Manhica n=75
NCT02411994 COMPLETED
Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria
Royal Tropical Institute n=197
NCT02654730 TERMINATED
Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia
London School of Hygiene and Tropical Medicine n=61
NCT02605720 COMPLETED
Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns
Lihir Medical Centre n=78
NCT01785979 WITHDRAWN
Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly
Lihir Medical Centre
NCT02461186 WITHDRAWN
Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern Myanmar
University of Oxford

Data: ClinicalTrials.gov