NCT03866382 RECRUITING Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
National Cancer Institute (NCI)
NCT05616650 RECRUITING Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor
National Cancer Institute (NCI)
NCT04550494 RECRUITING Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
National Cancer Institute (NCI)
NCT07450599 NOT YET RECRUITING A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Before Surgery for Men Who Have High-risk Localized Prostate Cancer.
Bayer
NCT06675357 RECRUITING Using FAPI PET/MRI to Evaluate Prostate Cancer
University of Wisconsin, Madison
NCT05726292 RECRUITING A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
University of Chicago
NCT06022822 RECRUITING Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial
National Cancer Institute (NCI)
NCT07441837 NOT YET RECRUITING Terbium 161 PSMA in Lutetium-177 PSMA Naive Patients
Ankara University
NCT05586360 RECRUITING T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer
Medical University of South Carolina
NCT05828082 ACTIVE NOT RECRUITING Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer
National Cancer Institute (NCI)
NCT04071236 RECRUITING Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy
National Cancer Institute (NCI)
NCT03938649 ACTIVE NOT RECRUITING SRAM study_Postate Cancer
CCTU
NCT05691465 RECRUITING Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
National Cancer Institute (NCI)
NCT06632977 RECRUITING Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
Alliance for Clinical Trials in Oncology
NCT05849298 ACTIVE NOT RECRUITING A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC
Novartis Pharmaceuticals
NCT05546268 ACTIVE NOT RECRUITING Study of Oral MRT-2359 in Selected Cancer Patients
Monte Rosa Therapeutics, Inc
NCT07230106 RECRUITING A Study of SHR3680, HS-20093 and SHR2554 in Subjects With Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT07005154 RECRUITING A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Astellas Pharma Global Development, Inc.
NCT07025369 RECRUITING Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial
Mayo Clinic
NCT04530552 ACTIVE NOT RECRUITING Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland
National Cancer Institute (NCI)
NCT07224009 NOT YET RECRUITING Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)
University of Arkansas
NCT06353386 RECRUITING Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)
Merck Sharp & Dohme LLC
NCT05413850 RECRUITING Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
Blue Earth Therapeutics Ltd
NCT07441889 NOT YET RECRUITING HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)
University of Virginia
NCT06237179 RECRUITING Behavioral Exercise Training to Reduce Cardiovascular Disease Risk
Virginia Commonwealth University
NCT07190300 RECRUITING TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Novartis Pharmaceuticals
NCT07206056 RECRUITING An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
Novartis Pharmaceuticals
NCT06395753 RECRUITING A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer
Debiopharm International SA
NCT03344211 ACTIVE NOT RECRUITING Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer
University of Southern California
NCT05125016 RECRUITING A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer
Regeneron Pharmaceuticals
NCT06957691 RECRUITING Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Shehzad Basaria, M.D.
NCT05751941 RECRUITING Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT06533644 RECRUITING A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer
Syncromune, Inc.
NCT04104893 ACTIVE NOT RECRUITING A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation
VA Office of Research and Development
NCT04422132 ACTIVE NOT RECRUITING Randomized Phase II Trial of Salvage Radiotherapy for Prostate Cancer In 4 Weeks v. 2 Weeks
Weill Medical College of Cornell University
NCT06849544 RECRUITING Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection
Clinton Bahler
NCT07142551 NOT YET RECRUITING Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07247175 RECRUITING The Impact of Force Feedback in the dV5 Robotic Surgical System on Learning Curve and Safety in Robot-Assisted Radical Prostatectomy - A Prospective, Single-Center, Investigator-Initiated Clinical Trial
Seong Soo Jeon
NCT06004661 RECRUITING Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function
Novartis Pharmaceuticals
NCT02522715 ACTIVE NOT RECRUITING Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer
OHSU Knight Cancer Institute
NCT07288359 RECRUITING Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Novartis Pharmaceuticals
NCT06378346 RECRUITING GU-01: Glycyrrhizin in Prostate Cancer
University of Illinois at Chicago
NCT07192614 RECRUITING A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
AstraZeneca
NCT07285057 RECRUITING Diagnostic Utility of rhPSMA-7.3 (18F) PET/CT in Men With Prostate Cancer on Active Surveillance
Icahn School of Medicine at Mount Sinai
NCT06267729 RECRUITING Study of AZD0754 in Participants With Metastatic Prostate Cancer
AstraZeneca
NCT06526299 RECRUITING Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease
University of Washington
NCT04337580 RECRUITING Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer
Wake Forest University Health Sciences
NCT05720130 RECRUITING Phase Ib/IIa Dose Escalation and Expansion Study of [²¹²Pb]Pb-ADVC001 in Metastatic Prostate Cancer (TheraPb - Phase I/II Study).
AdvanCell Pty Limited
NCT07111507 RECRUITING A Study of Tarlatamab for People With Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT04751929 ACTIVE NOT RECRUITING Abemaciclib With or Without Atezolizumab for mCRPC
Dana-Farber Cancer Institute
NCT03317392 ACTIVE NOT RECRUITING Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis
National Cancer Institute (NCI)
NCT06457919 RECRUITING A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT04644068 ACTIVE NOT RECRUITING Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
AstraZeneca
NCT06616597 RECRUITING Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07332000 RECRUITING A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec
Candel Therapeutics, Inc.
NCT04947254 RECRUITING Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer
M.D. Anderson Cancer Center
NCT06798558 RECRUITING Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy
Hackensack Meridian Health
NCT06111313 RECRUITING The University of Miami Adapt (UAdapt) Trial
University of Miami
NCT07287150 RECRUITING A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Hoffmann-La Roche
NCT03933670 RECRUITING Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance
University of California, San Francisco
NCT07410494 RECRUITING Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Essen Biotech
NCT06991556 RECRUITING An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Novartis Pharmaceuticals
NCT04506567 ACTIVE NOT RECRUITING Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC
Weill Medical College of Cornell University
NCT06990542 RECRUITING Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer
University of California, San Diego
NCT07234981 NOT YET RECRUITING PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Patients With Recurrent Prostate Cancer After Prostatectomy
University of Nebraska
NCT07226986 RECRUITING A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC
Novartis Pharmaceuticals
NCT07414940 NOT YET RECRUITING ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium
University College, London
NCT07415135 NOT YET RECRUITING Safety and Efficacy of PSMA-Targeted Fluorescent Contrast Agent DGPR1008 for Intraoperative Imaging in Robot-Assisted Radical Prostatectomy
Zhu Yinjie
NCT06894511 ACTIVE NOT RECRUITING An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC
Novartis Pharmaceuticals
NCT07145255 RECRUITING Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
MBrace Therapeutics
NCT03263650 ACTIVE NOT RECRUITING Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC
M.D. Anderson Cancer Center
NCT06236139 RECRUITING Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
Fred Hutchinson Cancer Center
NCT02861573 RECRUITING Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Merck Sharp & Dohme LLC
NCT05670106 ACTIVE NOT RECRUITING A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC
Novartis Pharmaceuticals
NCT04754191 ACTIVE NOT RECRUITING Enfortumab Vedotin as Monotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer
University of Utah
NCT05320406 ACTIVE NOT RECRUITING RElugolix VErsus LeUprolide Cardiac Trial
Emory University
NCT04558866 ACTIVE NOT RECRUITING Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)
Latin American Cooperative Oncology Group
NCT04848337 ACTIVE NOT RECRUITING Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer
University of Michigan Rogel Cancer Center
NCT07407283 NOT YET RECRUITING A Clinical Study of SHR-4394 in Combination With Anti-tumor Therapy in Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT06842498 RECRUITING A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Kyntra Bio
NCT07181161 RECRUITING Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
AstraZeneca
NCT03360721 ACTIVE NOT RECRUITING Apalutamide, Abiraterone Acetate, and Prednisone in Treating Participants With Metastatic Castration Resistant Prostate Cancer
M.D. Anderson Cancer Center
NCT07259213 NOT YET RECRUITING A Study of Terbium 161 (161Tb)-RAD402 in Participants With CRPC
Radiopharm Theranostics, Ltd
NCT04585750 RECRUITING The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
PMV Pharmaceuticals, Inc
NCT05919264 RECRUITING FOG-001 in Locally Advanced or Metastatic Solid Tumors
Parabilis Medicines, Inc.
NCT05059236 ACTIVE NOT RECRUITING A Study to Learn How Well Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works in Men With Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study.
Bayer
NCT06909825 ACTIVE NOT RECRUITING FPI-2265 (225Ac-PSMA-I&T) and Olaparib for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Fusion Pharmaceuticals Inc.
NCT04478279 ACTIVE NOT RECRUITING A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
Sapience Therapeutics
NCT07393867 NOT YET RECRUITING Androgen-responsive POSLUMA-guided Intra-prostatic Boost
Martin T. King, MD, PhD
NCT05751434 ACTIVE NOT RECRUITING A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT04704505 RECRUITING Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06591819 RECRUITING Hypofractionated WPPT With HDR Boost
Abramson Cancer Center at Penn Medicine
NCT07325721 RECRUITING Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer
Medical University of South Carolina
NCT03902951 ACTIVE NOT RECRUITING Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer
Jonsson Comprehensive Cancer Center
NCT04868604 RECRUITING 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
Clarity Pharmaceuticals Ltd
NCT05478239 ACTIVE NOT RECRUITING ArtemiCoffee in Patients With Rising PSA
Zin W Myint
NCT07001241 RECRUITING Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
University of Colorado, Denver
NCT03824652 RECRUITING WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy
Stephen Freedland
NCT02955082 ACTIVE NOT RECRUITING The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment
Institute of Cancer Research, United Kingdom
NCT07387510 NOT YET RECRUITING PSMA-Targeted Intraoperative Fluorescent Imaging Agents (DGPR1008): Validation Across Different Time Windows
Haitao Niu, MD
NCT07223385 NOT YET RECRUITING High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe)
Cedars-Sinai Medical Center
NCT04946370 ACTIVE NOT RECRUITING Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer
Weill Medical College of Cornell University
NCT05534646 RECRUITING Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer
Edwin Posadas, MD
NCT04300855 ACTIVE NOT RECRUITING Clinical Trial of Green Tea Catechins in Men on Active Surveillance
H. Lee Moffitt Cancer Center and Research Institute
NCT05568550 RECRUITING Pembro With Radiation With or Without Olaparib
Zin W Myint
NCT04997018 ACTIVE NOT RECRUITING A Study of MRI-guided High-dose Radiation Therapy in Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT03419234 ACTIVE NOT RECRUITING Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel
ECOG-ACRIN Cancer Research Group
NCT07365423 NOT YET RECRUITING Terbinafine for Biochemically Recurrent Prostate Cancer (TerbinaPro)
Swiss Cancer Institute
NCT03543189 ACTIVE NOT RECRUITING Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy
H. Lee Moffitt Cancer Center and Research Institute
NCT05806515 RECRUITING Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
SWOG Cancer Research Network
NCT06397703 RECRUITING ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
NYU Langone Health
NCT03796767 ACTIVE NOT RECRUITING Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer
University of Utah
NCT06145633 RECRUITING Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer
Fred Hutchinson Cancer Center
NCT04989946 RECRUITING Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer
University of Wisconsin, Madison
NCT07073794 RECRUITING Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer
Mayo Clinic
NCT04734730 RECRUITING Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer
City of Hope Medical Center
NCT07210086 RECRUITING Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)
City of Hope Medical Center
NCT06172478 RECRUITING A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Daiichi Sankyo
NCT06926075 RECRUITING Early Phase Study of Kesonotide in Participants With Solid Tumours
Filamon LTD
NCT06836726 NOT YET RECRUITING Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resistant Prostate Cancer
University Health Network, Toronto
NCT03424850 RECRUITING Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy
Washington University School of Medicine
NCT06111781 RECRUITING The SUGAR Study; SBRT and Relugolix) for Prostate Cancer
Yale University
NCT05968144 ACTIVE NOT RECRUITING Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness
University of Maryland, Baltimore
NCT07364071 NOT YET RECRUITING Strategic Endocrine Therapy and Targeted Radiotherapy for Prostate Cancer
University of California, San Diego
NCT04402151 RECRUITING Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer
Weill Medical College of Cornell University
NCT05502315 RECRUITING Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer
Rana McKay, MD
NCT07363486 RECRUITING Sequential Study of 225Ac-LNC1011 in the Treatment of Metastatic Castration-Resistant Prostate Cancer
First Affiliated Hospital of Fujian Medical University
NCT07363382 RECRUITING The Value of GRPR PET Imaging for Diagnosis and Staging in Prostate Cancer
First Affiliated Hospital of Fujian Medical University
NCT05498272 RECRUITING Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations
Rana McKay, MD
NCT03246347 ACTIVE NOT RECRUITING A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer
Wake Forest University Health Sciences
NCT04126070 ACTIVE NOT RECRUITING Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors
Xiao X. Wei, MD
NCT06906471 NOT YET RECRUITING A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS
Antelope Surgical Solutions, Inc
NCT03181867 ENROLLING BY INVITATION 18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer
National Cancer Institute (NCI)
NCT07354919 NOT YET RECRUITING Axelopran in Advanced Cancers
HealthPartners Institute
NCT03333616 ACTIVE NOT RECRUITING Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors
Dana-Farber Cancer Institute
NCT03173924 ACTIVE NOT RECRUITING 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer
National Cancer Institute (NCI)
NCT05133440 ACTIVE NOT RECRUITING A Study of Stereotactic Body Radiation Therapy and Radium (Ra-223) Dichloride in Prostate Cancer That Has Spread to the Bones
Memorial Sloan Kettering Cancer Center
NCT06734130 ACTIVE NOT RECRUITING Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT07292168 RECRUITING A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1
Kidney Cancer Research Bureau
NCT07354594 NOT YET RECRUITING External Beam and Radioligand Radiotherapy for mCRPC
Centre hospitalier de l'Université de Montréal (CHUM)
NCT03456843 ACTIVE NOT RECRUITING Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer
Yale University
NCT04267887 ACTIVE NOT RECRUITING Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer
OHSU Knight Cancer Institute
NCT05038332 RECRUITING Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])
University of Michigan Rogel Cancer Center
NCT06085664 RECRUITING A Pilot Presurgical Trial of REGN5678 (Anti-PSMA x CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy
M.D. Anderson Cancer Center
NCT07189871 RECRUITING 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors
Radiopharm Theranostics, Ltd
NCT05826509 ACTIVE NOT RECRUITING SUrGery With or Without dARolutamide in High-risk and/or Locally Advanced Prostate Cancer
Institut Claudius Regaud
NCT07341737 NOT YET RECRUITING SL-28 for Advanced Solid Tumours
Second Life Therapeutics
NCT06334432 ACTIVE NOT RECRUITING Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
Nuvation Bio Inc.
NCT03371719 ACTIVE NOT RECRUITING Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial
NRG Oncology
NCT04206319 ACTIVE NOT RECRUITING Radium-223 in Biochemically Recurrent Prostate Cancer
National Cancer Institute (NCI)
NCT06039371 RECRUITING Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study
University of Washington
NCT05924672 ACTIVE NOT RECRUITING Efficacy of Ra-223 in PSMA PET Optimally Selected Patients
University of California, San Francisco
NCT05053152 RECRUITING Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study
NRG Oncology
NCT06059118 RECRUITING Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07336446 NOT YET RECRUITING A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs
AstraZeneca
NCT07335796 RECRUITING A Study of BMS986365 in Combination With Degarelix in People With Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT06854250 RECRUITING Prostate Cryoablation Combined With Metronomic Cyclophosphamide for Metastatic Prostate Cancer
Sun Yat-sen University
NCT06347705 RECRUITING A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT07285694 RECRUITING AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)
Arsenal Biosciences, Inc.
NCT04686682 RECRUITING A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors
Jacobio Pharmaceuticals Co., Ltd.
NCT04777071 ACTIVE NOT RECRUITING An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer
University of Washington
NCT06066437 RECRUITING NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial
M.D. Anderson Cancer Center
NCT05570994 ENROLLING BY INVITATION 177Lu-HTK03170 in mCRPC With PSMA Positive Disease
British Columbia Cancer Agency
NCT06970119 RECRUITING A Multicenter, Open-label, Non-randomized Phase I/IIa Clinical Trial to Evaluate INR102 Injection in Patients With Prostate Cancer
Yunhe Pharmaceutical (Tianjin) Co., Ltd
NCT06600698 RECRUITING Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA
Milton S. Hershey Medical Center
NCT06399757 RECRUITING A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
Apollo Therapeutics Ltd
NCT06630325 ACTIVE NOT RECRUITING A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer
OHSU Knight Cancer Institute
NCT05689021 ACTIVE NOT RECRUITING CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations
Mayo Clinic
NCT02949284 ACTIVE NOT RECRUITING Androgen Receptor Antagonist ARN-509 With or Without Abiraterone Acetate, Gonadotropin-Releasing Hormone Analog, and Prednisone in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery
Rutgers, The State University of New Jersey
NCT06391034 RECRUITING Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer
Robert Bok, MD, PhD
NCT07302451 ACTIVE NOT RECRUITING REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients)
National Cancer Institute, Naples
NCT06866938 RECRUITING Study of Re-treatment With [177Lu]Lu-PSMA in Men With Metastatic Castration Resistance Prostate Cancer
Hospices Civils de Lyon
NCT06084338 RECRUITING Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc
VA Office of Research and Development
NCT07313241 RECRUITING Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)
University of Texas Southwestern Medical Center
NCT06568094 RECRUITING A Study of HRS-5041 Tablets Combined With Antitumor Therapy in Subjects With Advanced Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT07310355 NOT YET RECRUITING 68Ga-PSMA-0057 and 177Lu-PSMA-0057 in Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer
Chengdu StarRay Therapeutics Co., Ltd
NCT06384222 RECRUITING Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone
Ivan de Kouchkovsky, MD
NCT05766371 RECRUITING Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer
University of California, San Francisco
NCT03809000 ACTIVE NOT RECRUITING A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery
RTOG Foundation, Inc.
NCT07310433 NOT YET RECRUITING Dapagliflozin Combined With Next-generation Hormonal Agent (NHA) Versus Single NHA in Participants With Metastatic Castrate-resistant Prostate Cancer
Yung NA
NCT06380660 RECRUITING Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
Acerand Therapeutics (Shanghai) Limited
NCT06378866 RECRUITING Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial
Mayo Clinic
NCT07300566 NOT YET RECRUITING Focal Versus Whole Gland High Dose-Rate Brachytherapy (HDR-BT) Boost to External Beam Radiotherapy in Localized Prostate Cancer: A Phase 2 Randomized Trial
Joelle Helou
NCT03431350 ACTIVE NOT RECRUITING A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Janssen Research & Development, LLC
NCT04592237 ACTIVE NOT RECRUITING Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer
M.D. Anderson Cancer Center
NCT05873192 RECRUITING Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer
M.D. Anderson Cancer Center
NCT07299292 RECRUITING Castration With Abiraterone 250 mg Without LHRH Analogs or Blockers in Patients With Prostate Cancer Requiring Hormonal Intensification (Multicenter Phase 2)
SMED Clinical Research
NCT04655365 ACTIVE NOT RECRUITING Detecting Metastases by PyL PET/CT in Subjects Starting Enzalutamide for Untreated Castration Resistant Prostate Cancer.
CHU de Quebec-Universite Laval
NCT06228053 RECRUITING Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer
Syntrix Biosystems, Inc.
NCT05983198 ACTIVE NOT RECRUITING Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT
Novartis Pharmaceuticals
NCT06155084 RECRUITING A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients
Hinova Pharmaceuticals Inc.
NCT05241860 ACTIVE NOT RECRUITING Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)
Alliance for Clinical Trials in Oncology
NCT03753334 ACTIVE NOT RECRUITING Effects of EPA in Men With Biochemical Recurrence or Progression of Prostate Cancer.
CHU de Quebec-Universite Laval
NCT02452008 ACTIVE NOT RECRUITING Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04175431 RECRUITING Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
University of Washington
NCT07291557 NOT YET RECRUITING PSMA-PET Directed Radiation Therapy for High-Risk Prostate Cancer
AHS Cancer Control Alberta
NCT03976843 ACTIVE NOT RECRUITING Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
National Cancer Institute (NCI)
NCT06807359 RECRUITING Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System
SpectraCure AB
NCT07150715 RECRUITING Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma
Jonsson Comprehensive Cancer Center
NCT02960022 RECRUITING A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
Astellas Pharma Global Development, Inc.
NCT06609005 RECRUITING A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer
Shenzhen Ionova Life Sciences Co., Ltd.
NCT05114746 RECRUITING Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan
Novartis Pharmaceuticals
NCT07282197 NOT YET RECRUITING Darolutamide+ADT Post-RP w/o ePLND in hrPC: Briganti 2019
Peking University First Hospital
NCT04025372 ACTIVE NOT RECRUITING INTREPId (INTermediate Risk Erection PreservatIon Trial)
Brigham and Women's Hospital
NCT03833921 RECRUITING Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer
Martha Mims
NCT06943521 RECRUITING A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Tanabe Pharma America, Inc.
NCT06568562 RECRUITING XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer
University of Utah
NCT05367440 ACTIVE NOT RECRUITING Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
AstraZeneca
NCT06616155 RECRUITING Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
University of Michigan Rogel Cancer Center
NCT07255664 RECRUITING A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC
Curacell Holding AB
NCT07268794 NOT YET RECRUITING CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer
Fudan University
NCT04536805 RECRUITING Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin
Institut Cancerologie de l'Ouest
NCT04090528 ACTIVE NOT RECRUITING pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant, Metastatic Prostate Cancer
University of Wisconsin, Madison
NCT05189457 ACTIVE NOT RECRUITING First Strike, Second Strike Therapies for High Risk Metastatic Castration Sensitive Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT07002320 RECRUITING Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer
Institute of Cancer Research, United Kingdom
NCT05893381 RECRUITING Lu-PSMA and Stereotactic Radiotherapy Versus Radiotherapy Alone for Prostate Cancer (LUST)
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT05682443 ACTIVE NOT RECRUITING ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
OncoC4, Inc.
NCT03436654 ACTIVE NOT RECRUITING Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma
Memorial Sloan Kettering Cancer Center
NCT06029998 RECRUITING Bortezomib in Patients With Metastatic Castration-Resistant Prostate Cancer With PTEN Deletion
University of Utah
NCT07250542 RECRUITING A Clinical Study on the Efficacy and Safety of Fasudil Hydrochloride Combined With Immunotherapy in the Treatment of Metastatic Castration-resistant Prostate Cancer
baotai Liang
NCT06594926 RECRUITING Working Out M0 Bipolar Androgen Therapy
Australian and New Zealand Urogenital and Prostate Cancer Trials Group
NCT07251829 NOT YET RECRUITING Neoadjuvant Embolization and Cytoreduction in Prostate Cancer
Srinivas Raman
NCT04190446 ACTIVE NOT RECRUITING A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer
Mayo Clinic
NCT05848011 ACTIVE NOT RECRUITING A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate Cancer
MacroGenics
NCT06400160 NOT YET RECRUITING Clinical Trial of TB511 in Advanced Solid Tumors
Twinpig Biolab, Inc.
NCT06574880 RECRUITING STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer
Angela Y. Jia, MD PhD
NCT06126731 RECRUITING Combination Study of Antibiotics With Enzalutamide (PROMIZE)
Institute of Cancer Research, United Kingdom
NCT02333435 ACTIVE NOT RECRUITING Effects of EPA on Prostate Cancer Cells Proliferation and Quality of Life
CHU de Quebec-Universite Laval
NCT07164794 NOT YET RECRUITING Memantine Hydrochloride in Prostate Cancer Patients
Bin Xu
NCT07237269 NOT YET RECRUITING Abiraterone/Prednisone + Standard ADT vs Standard ADT for Prostate Cancer Patients With PSMA-Positive Conventional Imaging Negative Pelvic Lymphadenopathy
University of Nebraska
NCT06654336 NOT YET RECRUITING Study of Recurrence-directed Therapy (RDT) With or Without Androgen-Deprivation Therapy (ADT) In Patients With Radio-recurrent Oligo-metastatic Hormone/Castrate Sensitive Prostate Cancer (romCSPC)
Ontario Clinical Oncology Group (OCOG)
NCT07163910 RECRUITING Homoharringtonine Plus Androgen Deprivation Therapy in the Neoadjuvant Treatment of Prostate Cancer: A Single-Arm Clinical Study
baotai Liang
NCT06369610 RECRUITING Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer
Mayo Clinic
NCT05454488 RECRUITING An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer
M.D. Anderson Cancer Center
NCT07025512 RECRUITING 177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia
M.D. Anderson Cancer Center
NCT06785636 RECRUITING Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617
Pathos AI, Inc.
NCT06615752 RECRUITING Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients
Charles Drew University of Medicine and Science
NCT06150417 RECRUITING MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)
Case Comprehensive Cancer Center
NCT06536374 NOT YET RECRUITING Folate Study in Men With Advanced Prostate Cancer
University of California, San Diego
NCT07226713 NOT YET RECRUITING Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors
Medical College of Wisconsin
NCT02703623 ACTIVE NOT RECRUITING Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
M.D. Anderson Cancer Center
NCT05223803 RECRUITING TERPS Trial for de Novo Oligometastic Prostate Cancer
University of Maryland, Baltimore
NCT03972657 RECRUITING A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
Regeneron Pharmaceuticals
NCT03541850 ACTIVE NOT RECRUITING Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery
Jonsson Comprehensive Cancer Center
NCT04663997 ACTIVE NOT RECRUITING 177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer
Canadian Cancer Trials Group
NCT05100472 ACTIVE NOT RECRUITING A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT04335682 ACTIVE NOT RECRUITING Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide
Alliance Foundation Trials, LLC.
NCT06100705 RECRUITING Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC
Yale University
NCT05960578 RECRUITING Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study
University of Washington
NCT07216248 RECRUITING Optimal PSA Triggered Individual Management of Androgen Sensitive Prostate Cancer
University of Utah
NCT06844383 RECRUITING A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate
Prostate Cancer Clinical Trials Consortium
NCT06014255 RECRUITING Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04519879 ACTIVE NOT RECRUITING White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA
City of Hope Medical Center
NCT05779943 ACTIVE NOT RECRUITING Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer
Emory University
NCT03412396 ACTIVE NOT RECRUITING Apalutamide in Treating Patients With Prostate Cancer Before Radical Prostatectomy
M.D. Anderson Cancer Center
NCT03217747 ACTIVE NOT RECRUITING Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT06244004 RECRUITING FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial
Northwestern University
NCT06499870 RECRUITING Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
Northwestern University
NCT03012321 ACTIVE NOT RECRUITING Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects
Northwestern University
NCT06096870 RECRUITING Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy
National Cancer Institute (NCI)
NCT03517969 ACTIVE NOT RECRUITING M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
National Cancer Institute (NCI)
NCT06800313 RECRUITING A Study of HLD-0915 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
Halda Therapeutics OpCo, Inc.
NCT05540392 ACTIVE NOT RECRUITING An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues
Memorial Sloan Kettering Cancer Center
NCT03821792 ACTIVE NOT RECRUITING Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer
M.D. Anderson Cancer Center
NCT06402331 RECRUITING FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Fusion Pharmaceuticals Inc.
NCT05219500 ACTIVE NOT RECRUITING Targeted Alpha Therapy With 225Actinium-Prostate Specific Membrane Antigen (PSMA)-I&T of Castration-resISTant Prostate Cancer (TATCIST).
Fusion Pharmaceuticals Inc.
NCT07209865 RECRUITING 68Ga-P16-093 PET Imaging for Diagnosing Prostate Cancer, a Head-to-head Comparison With mpMRI
First Affiliated Hospital of Fujian Medical University
NCT05832086 RECRUITING Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
Stephen Freedland
NCT05869682 RECRUITING Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy
City of Hope Medical Center
NCT05036226 RECRUITING COAST Therapy in Advanced Solid Tumors and Prostate Cancer
Medical University of South Carolina
NCT07208240 RECRUITING Tb-PSMA-I&T Radionuclide Before Radical Prostatectomy in Patients With Locally Advanced Prostate Cancer - TbeforePROST Trial.
Rabin Medical Center
NCT06330805 RECRUITING Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer
Ohio State University Comprehensive Cancer Center
NCT05346848 RECRUITING Randomized Phase II Trial on Short Term Darolutamide Concomitant to Radiation Therapy for Patients With Intermediate Unfavorable Risk Prostate Cancer
Institut Bergonié
NCT04557449 ACTIVE NOT RECRUITING Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Pfizer
NCT07198633 NOT YET RECRUITING A Clinical Study of QLC5508 and/or QLH12016 in Combination With Other Anti-tumor Therapies in Subjects With Advanced Prostate Cancer
Qilu Pharmaceutical Co., Ltd.
NCT07192120 RECRUITING A Study of MHB048C in Patients With Advanced Solid Tumors
Minghui Pharmaceutical (Hangzhou) Ltd
NCT05652686 RECRUITING A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
Phanes Therapeutics
NCT02972060 ACTIVE NOT RECRUITING ODM-201 vs Androgen Deprivation Therapy in Hormone naïve Prostate Cancer
European Organisation for Research and Treatment of Cancer - EORTC
NCT07182279 RECRUITING Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer
The Methodist Hospital Research Institute
NCT07179783 RECRUITING Sacituzumab Tirumotecan in Combination With Tagitanlimab in the Treatment of Aggressive Variant Prostate Cancer (AVPC) and Neuroendocrine Prostate Cancer (NEPC)
Tianjin Medical University Second Hospital
NCT05113537 RECRUITING Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Vadim S Koshkin
NCT06922318 RECRUITING The COSMYC Trial (COmbined Suppression of MYC)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03042468 ACTIVE NOT RECRUITING Phase I Dose-escalation Study of Fractionated 177Lu-PSMA-617 for Progressive Metastatic CRPC
Weill Medical College of Cornell University
NCT04253483 ACTIVE NOT RECRUITING Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer
Rutgers, The State University of New Jersey
NCT07172126 NOT YET RECRUITING Clinical Trial to Evaluate the Tolerance of TQB3201 Tablets
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06200103 RECRUITING Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Mayo Clinic
NCT04709276 ACTIVE NOT RECRUITING A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer
Andrew J. Armstrong, MD
NCT03860987 ACTIVE NOT RECRUITING Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using Multiparametric MRI and 18FDCFPyL PET/CT in Newly Diagnosed Prostate Cancer
National Cancer Institute (NCI)
NCT06927635 RECRUITING Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer
University Health Network, Toronto
NCT06689163 RECRUITING A Study for the Treatment of Metastatic Prostate Cancer With HRS-1167 Tablets Combined With Abiraterone Acetate Tablets and Prednisone
Jiangsu HengRui Medicine Co., Ltd.
NCT06288113 RECRUITING Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial
Jonsson Comprehensive Cancer Center
NCT05722288 RECRUITING Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
City of Hope Medical Center
NCT03899987 ACTIVE NOT RECRUITING Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery
Roswell Park Cancer Institute
NCT06738303 RECRUITING Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer
Case Comprehensive Cancer Center
NCT06241846 RECRUITING A Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Patients With mCRPC
MediLink Therapeutics (Suzhou) Co., Ltd.
NCT06134232 RECRUITING Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T
Dendreon
NCT05011188 ACTIVE NOT RECRUITING FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer
Rahul Aggarwal
NCT06549465 RECRUITING Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)
Convergent Therapeutics
NCT06683846 RECRUITING Ivonescimab in the Treatment of Multiple Advanced Tumors
Fudan University
NCT05658003 ACTIVE NOT RECRUITING A Study Evaluating [177Lu]Lu-PSMA-617 vs. a Change of Androgen Receptor-directed Therapy in Taxane Treatment Naive Chinese Male Patients With Progressive Metastatic Castrate Resistant Prostate Cancer
Novartis Pharmaceuticals
NCT03385655 ACTIVE NOT RECRUITING Prostate Cancer Biomarker Enrichment and Treatment Selection
Canadian Cancer Trials Group
NCT04319783 ACTIVE NOT RECRUITING Darolutamide + Consolidation Radiotherapy in Advanced Prostate Cancer Detected by PSMA
Trans Tasman Radiation Oncology Group
NCT04038502 RECRUITING Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
VA Office of Research and Development
NCT04015622 ACTIVE NOT RECRUITING PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA
British Columbia Cancer Agency
NCT05864144 ACTIVE NOT RECRUITING A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Sensei Biotherapeutics, Inc.
NCT06401980 RECRUITING Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Swiss Cancer Institute
NCT03637543 ACTIVE NOT RECRUITING Nivolumab in Patients With High-Risk Biochemically Recurrent Prostate Cancer
Beth Israel Deaconess Medical Center
NCT07117760 RECRUITING Prospective Clinical Trial of 225Ac-LNC1011 in the Treatment of Metastatic Castration-Resistant Prostate Cancer
First Affiliated Hospital of Fujian Medical University
NCT05765500 RECRUITING RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
Dana-Farber Cancer Institute
NCT05057013 ACTIVE NOT RECRUITING A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours
Cancer Research UK
NCT07104617 NOT YET RECRUITING Study of TY-302 Capsules Combined With Abiraterone in Patients With Metastatic Castration-resistant Prostate Cancer(mCRPC)
TYK Medicines, Inc
NCT06395519 RECRUITING A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
858 Therapeutics, Inc.
NCT07104643 NOT YET RECRUITING Study of TYK-00540 Combined With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer(mCRPC)
TYK Medicines, Inc
NCT07104110 NOT YET RECRUITING Study of QLH12016 in Combination With Novel Hormonal Agent in Subjects With Advanced Prostate Cancer
Qilu Pharmaceutical Co., Ltd.
NCT05155046 RECRUITING 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
National Cancer Institute (NCI)
NCT07093866 RECRUITING Efficacy and Safety of Disitamab Vedotin Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer:a Phase II Study
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT02768363 ACTIVE NOT RECRUITING Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)
Candel Therapeutics, Inc.
NCT02893917 ACTIVE NOT RECRUITING Testing Two Oral Drugs Combination (Cediranib and Olaparib) Compared to a Single Drug (Olaparib) for Men With Advanced Prostate Cancer
National Cancer Institute (NCI)
NCT06610825 RECRUITING Castrate Resistant Prostate Cancer Enhertu Therapy
Washington D.C. Veterans Affairs Medical Center
NCT04037254 ACTIVE NOT RECRUITING Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring
NRG Oncology
NCT04698564 RECRUITING Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging
University of Maryland, Baltimore
NCT05842057 ACTIVE NOT RECRUITING Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy
University of Miami
NCT03436485 ACTIVE NOT RECRUITING Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer
Orion Corporation, Orion Pharma
NCT04471974 ACTIVE NOT RECRUITING ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Rahul Aggarwal
NCT02923180 ACTIVE NOT RECRUITING Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07068555 RECRUITING Prostate Cancer Vaccines
Shenzhen Geno-Immune Medical Institute
NCT06067269 RECRUITING Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Jonsson Comprehensive Cancer Center
NCT04363164 RECRUITING Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04343885 ACTIVE NOT RECRUITING In Men With Metastatic Prostate Cancer, What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy
Peter MacCallum Cancer Centre, Australia
NCT05560659 RECRUITING Lu-PSMA for Oligometastatic Prostate Cancer Treated With STereotactic Ablative Radiotherapy
Peter MacCallum Cancer Centre, Australia
NCT05489211 RECRUITING Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
AstraZeneca
NCT03204123 ACTIVE NOT RECRUITING PSMA PET Imaging of Recurrent Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT07056439 NOT YET RECRUITING Phase I/II Clinical Study of HRS-1738 for the Diagnosis of Prostate Cancer Patients
Jiangsu HengRui Medicine Co., Ltd.
NCT05011383 RECRUITING High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
VA Office of Research and Development
NCT06003556 RECRUITING PSMA-Guided Ablation of the Prostate
University of Alberta
NCT07048314 NOT YET RECRUITING Stem Cells for Erectile Dysfunction Post RALP
The Methodist Hospital Research Institute
NCT07038304 RECRUITING The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer (CRPC)
University Medical Center Groningen
NCT04249154 RECRUITING Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer
McGill University Health Centre/Research Institute of the McGill University Health Centre
NCT04915508 RECRUITING Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy
Jonsson Comprehensive Cancer Center
NCT06239194 RECRUITING Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
ModeX Therapeutics, An OPKO Health Company
NCT05191680 RECRUITING TherApeutics in Early ProState Cancer (TAPS02)
Cambridge University Hospitals NHS Foundation Trust
NCT03808077 ACTIVE NOT RECRUITING The Effect of Deep Versus Moderate Muscle Relaxants in Men During and After Robotic Surgery for Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT07027124 NOT YET RECRUITING Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer
Icahn School of Medicine at Mount Sinai
NCT07024277 NOT YET RECRUITING Study of ZG006 in Participants With Neuroendocrine Prostate Cancer
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NCT06402357 RECRUITING High Intensity Focused Ultrasound in Prostate Cancer
University of Florida
NCT06392295 RECRUITING PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer
University of Miami
NCT05790213 RECRUITING Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation
University of Chicago
NCT05944237 RECRUITING HTL0039732 in Participants With Advanced Solid Tumours
Cancer Research UK
NCT03682289 RECRUITING Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
Rahul Aggarwal
NCT02717156 ACTIVE NOT RECRUITING Multicohort Phase II Trial of sEphB4-HSA+Pembrolizumab in Solid Tumors
University of Southern California
NCT04194554 ACTIVE NOT RECRUITING A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer
University of Michigan Rogel Cancer Center
NCT03525262 ACTIVE NOT RECRUITING Prostate Oncologic Therapy While Ensuring Neurovascular Conservation (POTEN-C)
University of Texas Southwestern Medical Center
NCT06992232 RECRUITING Radiotherapy or Surgery Combined With Intense Androgen Deprivation Therapy for mCRPC
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT04140526 ACTIVE NOT RECRUITING Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
OncoC4, Inc.
NCT06383052 ACTIVE NOT RECRUITING A Phase 1/2 Study of 177Lu-NYM032 Injection in mCRPC
Norroy Bioscience Co., LTD
NCT04984343 ACTIVE NOT RECRUITING Randomized Trial of Five or Two MRI-Guided Adaptive Radiotherapy Treatments for Prostate Cancer
Weill Medical College of Cornell University
NCT04007770 ACTIVE NOT RECRUITING Acupuncture Pilot Study for Cancer-related Cognitive Function
Memorial Sloan Kettering Cancer Center
NCT05915442 RECRUITING Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer
Catherine Spina
NCT04925648 RECRUITING Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction
St Vincent's Hospital, Sydney
NCT04104776 RECRUITING A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Novartis Pharmaceuticals
NCT03522064 RECRUITING Bipolar Androgen Therapy + Carboplatin in mCRPC
St Vincent's Hospital, Sydney
NCT06972628 RECRUITING Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617
Ebrahim S Delpassand
NCT03821246 RECRUITING Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
David Oh
NCT03673787 ACTIVE NOT RECRUITING A Trial of Ipatasertib in Combination With Atezolizumab
Institute of Cancer Research, United Kingdom
NCT06971211 RECRUITING Radiotherapy Combined With Fluzopanib and Abiraterone Acetate Tablets (II) Treatment for mCRPC
Jianbin Bi
NCT03725761 ACTIVE NOT RECRUITING Sacituzumab Govitecan in Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Second Generation AR-Directed Therapy
University of Wisconsin, Madison
NCT05496959 ACTIVE NOT RECRUITING 177-Lutetium-PSMA Before Stereotactic Body Radiotherapy for the Treatment of Oligorecurrent Prostate Cancer, The LUNAR Study
Jonsson Comprehensive Cancer Center
NCT02905318 ACTIVE NOT RECRUITING Palbociclib in Patients With Metastatic Castration-Resistant Prostate Cancer
Canadian Cancer Trials Group
NCT06139575 RECRUITING Phase 1/2 Clinical Study of Lutetium Lu 177 JH020002 Injection in Patients With Advanced Prostate Cancer
Bivision Pharmaceuticals, Inc.
NCT03600350 ACTIVE NOT RECRUITING pTVG-HP and Nivolumab in Patients With Non-Metastatic PSA-Recurrent Prostate Cancer
University of Wisconsin, Madison
NCT05169970 RECRUITING A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT05168618 RECRUITING Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial
University of Utah
NCT06765954 NOT YET RECRUITING Immunotherapy With N 803, ETBX-071, and M-CENK in Combination With Radiation for Participants With High-Risk Prostate Cancer.
ImmunityBio, Inc.
NCT04253262 ACTIVE NOT RECRUITING A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer
Brown University
NCT04743934 ACTIVE NOT RECRUITING Flibanserin in Men Receiving Androgen Suppression for Prostate Cancer
Andrew McDonald
NCT06765902 NOT YET RECRUITING Immunotherapy Before and After Surgery
ImmunityBio, Inc.
NCT03361735 ACTIVE NOT RECRUITING Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer
City of Hope Medical Center
NCT04503265 RECRUITING A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
AtlasMedx, Incorporated
NCT06212583 RECRUITING High-Risk Metachronous Oligometastatic Prostate Cancer Trial
University of Maryland, Baltimore
NCT03689699 ACTIVE NOT RECRUITING Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8)
Mark Stein
NCT04262154 ACTIVE NOT RECRUITING Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT06463457 ACTIVE NOT RECRUITING Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)
Atish Choudhury, MD
NCT03951831 ACTIVE NOT RECRUITING REGN2810 Followed by Chemoimmunotherapy for Newly Metastatic Hormone-sensitive Prostate Cancer
Mark Stein
NCT06702995 RECRUITING Study of XNW5004 Tablet in Combination With Enzalutamide in Subjects With Metastatic Castration-Resistant Prostate Cancer
Evopoint Biosciences Inc.
NCT04619069 ACTIVE NOT RECRUITING Intermittent Androgen Deprivation Therapy With or Without Stereotactic Body Radiotherapy for Molecularly Identified Hormone Sensitive Oligometastatic Prostate Cancer
Sunnybrook Health Sciences Centre
NCT05593497 RECRUITING A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
VA Office of Research and Development
NCT06480110 RECRUITING Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate Cancer
Rigshospitalet, Denmark
NCT05521412 RECRUITING EValuation of radIOLigand Treatment in mEn With Metastatic Castration-resistant Prostate Cancer With [161Tb]Tb-PSMA-I&T
Peter MacCallum Cancer Centre, Australia
NCT05340374 ACTIVE NOT RECRUITING Cabazitaxel in Combination With 177Lu-PSMA-617 in Metastatic Castration-resistant Prostate Cancer
Peter MacCallum Cancer Centre, Australia
NCT04969315 RECRUITING TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors
Portage Biotech
NCT06907641 RECRUITING Comparative Performance of 64Copper [64Cu]-SAR-bis-PSMA vs 68Ga PSMA-11 PET CT for the Detection of Prostate Cancer Recurrence in the Setting of Biochemical Failure Following Radical Prostatectomy
St Vincent's Hospital, Sydney
NCT04748042 ACTIVE NOT RECRUITING Focal Radiation With Pulsed Systemic Therapy of Abiraterone, Androgen Deprivation Therapy (ADT), Lynparza Towards Castration Sensitive Oligometastatic Prostate Cancer (FAALCON)
University of Michigan Rogel Cancer Center
NCT05896371 NOT YET RECRUITING A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy
CHU de Quebec-Universite Laval
NCT03787680 ACTIVE NOT RECRUITING Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial)
University of Michigan Rogel Cancer Center
NCT06890832 NOT YET RECRUITING A Study to Investigate Efficacy and Safety of Different Dose Regimen of Oral Cabazitaxel Tablet in Adult Participants with Prostate Cancer
Jina Pharmaceuticals Inc.
NCT06190899 RECRUITING Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer
Celcuity Inc
NCT04802876 ACTIVE NOT RECRUITING Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors
SOLTI Breast Cancer Research Group
NCT04145375 ENROLLING BY INVITATION Continuation Protocol for ZEN003694 in Patients Experiencing Clinical Benefit While Enrolled in a ZEN003694 Protocol
Zenith Epigenetics
NCT05067140 ACTIVE NOT RECRUITING A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer
Novartis Pharmaceuticals
NCT05457699 RECRUITING Ablative Radiotherapy to Consolidate Maximal Systemic Response in Metastatic Prostate Cancer (ANCHOR-Prostate)
Centre hospitalier de l'Université de Montréal (CHUM)
NCT04053842 ACTIVE NOT RECRUITING Multi-modality Imaging (PCa) Using Sodium MRI and PSMA PET in Men Pre-prostatectomy
Glenn Bauman
NCT04100174 RECRUITING Focal HDR Brachytherapy Boost to Stereotactic Radiotherapy
Centre hospitalier de l'Université de Montréal (CHUM)
NCT06582446 RECRUITING Artificial Intelligence to Personalize Prostate Cancer Treatment (the HypoElect Trial)
German Oncology Center, Cyprus
NCT03471650 ACTIVE NOT RECRUITING Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06437574 RECRUITING Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
Cedars-Sinai Medical Center
NCT06216249 RECRUITING Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)
Jonsson Comprehensive Cancer Center
NCT06832774 NOT YET RECRUITING Exploration of Treatment Effect of Novel Hormone Therapy Combined with Local Treatment Based on PSMA PET/CT Evaluation in MHSCP Patients
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
NCT06827080 NOT YET RECRUITING Study on the Safety, Tolerability, and Preliminary Efficacy of 161Tb-NYM032 in Patients with Metastatic Castration-Resistant Prostate Cancer
Zhengguo Chen
NCT06449781 RECRUITING 177Lu-PSMA as a Systemic Adjuvant Treatment in Patients With High and Very High Risk Prostate Cancer
Maria Sklodowska-Curie National Research Institute of Oncology
NCT05383079 ACTIVE NOT RECRUITING Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men with Metastatic Castration-Resistant Prostate Cancer
Peter MacCallum Cancer Centre, Australia
NCT03763253 ACTIVE NOT RECRUITING Additional Treatments to the Local Tumour for Metastatic Prostate Cancer: Assessment of Novel Treatment Algorithms
Imperial College London
NCT05032040 ACTIVE NOT RECRUITING A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies
Xencor, Inc.
NCT05888532 RECRUITING 64Cu-GRIP B in Patients With Advanced Malignancies
Rahul Aggarwal
NCT04986423 RECRUITING ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
Zenith Epigenetics
NCT06782555 RECRUITING A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab
ImmunoGenesis
NCT06783153 NOT YET RECRUITING Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients
Mansoura University
NCT04009967 ACTIVE NOT RECRUITING Biomarkers for Neoadjuvant Pembrolizumab in Non-Metastatic Prostate Cancer Positive by 18FDG-PET Scanning
CHU de Quebec-Universite Laval
NCT06772441 RECRUITING Artificial Intelligence Driven Personalisation of Radiotherapy and Concomitant Androgen Deprivation Therapy for Prostate Cancer Patients (the HypoPro Trial)
German Oncology Center, Cyprus
NCT06758882 RECRUITING Surgical Treatment With or Without Apalutamide in Subjects With High Risk Prostate Cancer Who Are Candidates for Radical Prostatectomy and Staged as Oligometastatic With PSMA-PET
Marco Oderda
NCT03315754 ACTIVE NOT RECRUITING Study of the Efficacy, Safety and Quality of Life After TOOKAD® Soluble (VTP) for Intermediate Risk Prostate Cancer.
Steba Biotech S.A.
NCT06738745 NOT YET RECRUITING Study of HRS-2189 Combined HRS-5041 in Prostate Cancer
Fudan University
NCT06173362 RECRUITING Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer
Mamta Parikh
NCT02807805 ACTIVE NOT RECRUITING Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer
Mamta Parikh
NCT04842890 ACTIVE NOT RECRUITING Phase II Study of Pencil Beam Scanning Proton Stereotactic Body Radiation Therapy for Prostate Cancer
The New York Proton Center
NCT04812366 RECRUITING Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
University of British Columbia
NCT05547061 ACTIVE NOT RECRUITING A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Dosimetry, and Anti-tumor Activity of Ga-68-NGUL / Lu-177-DGUL in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Refractory to Standard Therapy
Cellbion Co., Ltd.
NCT03569241 ACTIVE NOT RECRUITING PEACE V: Salvage Treatment of OligoRecurrent Nodal Prostate Cancer Metastases
University Hospital, Ghent
NCT06409910 RECRUITING ALTERNATE DAY ULTRAHYPOFRACTIONATED OR DAILY MODERATELY HYPOFRACTIONATED POST OPERATIVE RADIOTHERAPY (AMPORA)
University Health Network, Toronto
NCT04070209 RECRUITING Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)
Sir Mortimer B. Davis - Jewish General Hospital
NCT03067051 RECRUITING Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
SpectraCure AB
NCT06582628 RECRUITING Talazoparib Plus Enzalutamide After Progression to Abiraterone in Metastatic Prostate Cancer: (TEAM PC)
Fundacion Oncosur
NCT05393791 RECRUITING Phase II Randomised Controlled Trial of Patient-specific Adaptive vs. Continuous Abiraterone or eNZalutamide in mCRPC
Leiden University Medical Center
NCT05404139 RECRUITING Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)
University Health Network, Toronto
NCT06474806 RECRUITING Safety and Diagnostic Performance of uPAR PET Imaging in Localised, Untreated Prostate Cancer
Curasight
NCT04879563 ACTIVE NOT RECRUITING Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project
Region Örebro County
NCT04430192 ACTIVE NOT RECRUITING Dosimetry, Safety and Potential Benefit of 177Lu-PSMA-617 Prior to Prostatectomy
Peter MacCallum Cancer Centre, Australia
NCT06678126 NOT YET RECRUITING Adaptive Versus Non-adaptive Radiotherapy and 2 Bladder Filling Instructions for Patients with Intermediate or High Risk Localized Prostate Cancer (ARP)
Scott Tyldesley
NCT06663007 RECRUITING RC48 Monotherapy or Combination With Envafolimab for CDK12 Alterations mCRPC With Standard Treatment Failure
Tianjin Medical University Second Hospital
NCT06617481 RECRUITING PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence
AdventHealth
NCT06655259 RECRUITING Combination of TURP and Standard Systemic Therapy for MPCa
Fudan University
NCT05558007 RECRUITING Safety and Efficacy Evaluation of BZ371A Topically Applied on Prostatectomized Patients
Biozeus Biopharmaceutical S.A.
NCT06636682 RECRUITING FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer
Cellvax Therapeutics Inc
NCT04716725 ACTIVE NOT RECRUITING 68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer
Thomas Hope
NCT05946824 RECRUITING This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
University of Rochester
NCT03230734 ACTIVE NOT RECRUITING Sequencing of Radium-223 and Docetaxel in Symptomatic Bone-only Metastatic Castration-resistant Prostate Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT06575257 RECRUITING Neoadjuvant Therapy of Darolutamide Plus ADT for High Risk Prostate Cancer
Xijing Hospital
NCT06001255 RECRUITING ARTEMIS-003: HS-20093 in Patients With Metastatic Castrate-resistant Prostate Cancer (mCRPC) and Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT06505278 NOT YET RECRUITING The Impact of Medication Timing Adjustment on the Effect of Novel Hormonal Therapy
Sun Yat-sen University
NCT03795207 ACTIVE NOT RECRUITING Prostate Cancer With OligometaSTatic Relapse: Combining Stereotactic Ablative Radiotherapy and Durvalumab (MEDI4736)
Institut Cancerologie de l'Ouest
NCT06500247 NOT YET RECRUITING Darxicilib Combined With Abiraterone Acetate Tablets (II) for the Treatment of Advanced Metastatic Castration-resistant Prostate Cancer.
Qilu Hospital of Shandong University
NCT04731844 RECRUITING Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer
University of Rochester
NCT06484361 RECRUITING PET/MRI to Stage Prostate Cancer Patients
IRCCS San Raffaele
NCT04346225 RECRUITING Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer
Ivan de Kouchkovsky, MD
NCT03079323 RECRUITING Trial to Investigate the Benefit of Elective Para-Aortic Radiotherapy (PART) for pN1 Prostate Cancer
Universitaire Ziekenhuizen KU Leuven
NCT03080116 ACTIVE NOT RECRUITING Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy
Universitaire Ziekenhuizen KU Leuven
NCT05762536 RECRUITING Docetaxel or Cabazitaxel With or Without Darolutamide in mCRPC
Erasmus Medical Center
NCT04295447 ACTIVE NOT RECRUITING Adjuvant Apalutamide in Subjects With High-risk Localized or Locally Advanced Prostate Cancer After Radical Prostatectomy
Universität Münster
NCT05008900 RECRUITING Timing of Post-prostatectomy PSMA Imaging
University Health Network, Toronto
NCT05563558 RECRUITING Pembrolizumab, Carboplatin and Cabazitaxel in Aggressive Metastatic Castration Resistant Prostate Cancer (PEAPOD_FOS)
Fundacion Oncosur
NCT04147806 ACTIVE NOT RECRUITING A Pilot Study of Ultra-High-Dose Hypofractionated or Single-Dose Radiotherapy for Intermediate Risk Prostate Cancer
Albert Einstein College of Medicine
NCT06227156 RECRUITING Disitamab Vedotin in the Treatment With HER2- Expression, Subjects With Locally Advanced or Metastatic Castration-resistant Prostate Cancer
RemeGen Co., Ltd.
NCT03762759 ACTIVE NOT RECRUITING Fluciclovine F18 or Ga68-PSMA PET/CT to Enhance Prostate Cancer Outcomes
Emory University
NCT03141671 ACTIVE NOT RECRUITING Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)
Dana-Farber Cancer Institute
NCT04465500 RECRUITING EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer
University of Virginia
NCT06081686 RECRUITING Study of [177Lu] Lu-XT033 Injection in Patients With Metastatic Prostate Cancer
Sinotau Pharmaceutical Group
NCT05579184 ACTIVE NOT RECRUITING [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application_2
FutureChem
NCT05458544 RECRUITING [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
FutureChem
NCT06387056 RECRUITING Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO)
The First Affiliated Hospital of Xiamen University
NCT06385847 RECRUITING To Assess The Patient Preference for Goserelin Microsphere Versus Goserelin Implant in Patients With Prostate Cancer
The First Affiliated Hospital of Xiamen University
NCT03700099 ACTIVE NOT RECRUITING Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Treatment With Docetaxel Followed by Enzalutamide
Instituto do Cancer do Estado de São Paulo
NCT06343077 RECRUITING Intratumoral and Systemic Hiltonol® (Poly-ICLC) in Prostate Cancer Patients on Active Surveillance
Ashutosh Kumar Tewari
NCT04903873 RECRUITING A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors
Eutilex
NCT06305832 RECRUITING Salvage Radiotherapy Combined With Androgen Deprivation Therapy (ADT) With or Without Rezvilutamide in the Treatment of Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT03934840 ACTIVE NOT RECRUITING CASCARA: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone
Masonic Cancer Center, University of Minnesota
NCT06022757 RECRUITING Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)
Evopoint Biosciences Inc.
NCT06271551 NOT YET RECRUITING Transdermal Estradiol and Exercise in Mitigating Adverse Effects of Androgen Deprivation Therapy for Prostate Cancer Radiation Therapy
Central Finland Hospital District
NCT06259123 RECRUITING Neoadjuvant PSMA-RLT in Oligometastatic PCa
Medical University of Vienna
NCT06220188 RECRUITING PSMA-RLT in Biochemically Recurrent PCa
Medical University of Vienna
NCT06249750 RECRUITING Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer
Pengyuan Liu
NCT04176081 NOT YET RECRUITING Study of Radiation Therapy in Combination With Darolutamide + Degarelix in Intermediate Risk Prostate Cancer
University Health Network, Toronto
NCT05851547 RECRUITING Dose Escalation For INtraprostatic LEsions
Ottawa Hospital Research Institute
NCT04889742 NOT YET RECRUITING Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Charite University, Berlin, Germany
NCT06029036 RECRUITING A Phase II Neoadjuvant Study of Darolutamide Plus ADT in Men With Localized Prostate Cancer
Peking University First Hospital
NCT04045717 ACTIVE NOT RECRUITING Hypofractionated Focal Lesion Ablative Microboost in prostatE Cancer 2.0
Universitaire Ziekenhuizen KU Leuven
NCT06134271 NOT YET RECRUITING Rezvilutamide Plus Abiraterone for Metastatic Hormone-sensitive Prostate Cancer
Jianbin Bi
NCT06129851 NOT YET RECRUITING Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer
University of Kansas Medical Center
NCT06015321 NOT YET RECRUITING An Open Label Phase II Study of First-Line Maintenance Enzalutamide Following Docetaxel Plus Androgen-Deprivation Therapy in Patients With Previously-Untreated, Metastatic, Castration-Naive Prostatic Adenocarcinoma
Samsung Medical Center
NCT04197141 ACTIVE NOT RECRUITING Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
NCT02881242 ACTIVE NOT RECRUITING Trametinib in Treating Patients With Progressive Metastatic Hormone-Resistant Prostate Cancer
Jonsson Comprehensive Cancer Center
NCT05820724 NOT YET RECRUITING PSMA PET Scan and mpMRI for Prostate Cancer Detection
VA Greater Los Angeles Healthcare System
NCT05054296 RECRUITING Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
M.D. Anderson Cancer Center
NCT05778097 NOT YET RECRUITING Adjutant Apalutamide Plus ADT in Post-RP Patients With High Risk of Recurrence (ARES Study)
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT05003752 ACTIVE NOT RECRUITING Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer
German Oncology Center, Cyprus
NCT05753566 RECRUITING Rezvilutamide in Patients With Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT05717582 NOT YET RECRUITING Maximal Cytoreductive Therapies on Post-treatment Metastases in Pts With mHSPC During Apalutamide Plus ADT Treatment
Fudan University
NCT05373316 NOT YET RECRUITING Addition of a Focal Boost in External Beam Radiotherapy for Locally Advanced Prostate Cancer by Online Adaptive MR-guided Radiotherapy
Radboud University Medical Center
NCT05557604 RECRUITING Sbrt±sTad for Unfavorable iNtermediate rIsk/High Risk Prostate caNcer
Regina Elena Cancer Institute
NCT03061539 ACTIVE NOT RECRUITING Nivolumab and Ipilimumab Treatment in Prostate Cancer With an Immunogenic Signature
University College, London
NCT05406999 RECRUITING Neoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT03585114 ACTIVE NOT RECRUITING Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers
Columbia University
NCT03444844 ACTIVE NOT RECRUITING Biodistribution and Dosimetry of Ga-68 P16-093 in Prostate Cancer
Five Eleven Pharma, Inc.
NCT05010343 RECRUITING Functional Image-Guided Carbon Ion Irradiation With Simultaneous Integrated Boost for Prostate Cancer
Shanghai Proton and Heavy Ion Center
NCT04114825 ACTIVE NOT RECRUITING Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer
RhoVac APS
NCT04700332 RECRUITING PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer
Hoag Memorial Hospital Presbyterian
NCT04925063 NOT YET RECRUITING The Effect of Metformin in Patients With Newly Diagnosed mHSPC
Sun Yat-sen University
NCT04622761 NOT YET RECRUITING Phase II Study of the Use of Neoadjuvant Cabazitaxel With Hormonal Treatment in Patients Operable Prostate Cancer, Assess the Efficacy and Toxicity of Cabazitaxel, and Explore Potential Predictive and Prognostic Markers of Clinical Outcome
The Clatterbridge Cancer Centre NHS Foundation Trust
NCT03294889 RECRUITING ONE-SHOT Trial - Ultra-hypofractionated Single-dose SBRT for Prostate Cancer
University Hospital, Geneva
NCT04086290 RECRUITING National Danish Protocol. Surgery+ SBRT for M1 Prostate Cancer Patients
Peter Busch Østergren
NCT04212715 RECRUITING Prostate SABR With Intra-Prostatic SABR Boost
King Saud University
NCT03827616 ENROLLING BY INVITATION Moderately Hypofractionated Radiotherapy for Prostate Cancer.
Tatarstan Cancer Center
NCT03392233 RECRUITING Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors
RenJi Hospital
NCT04288687 COMPLETED A Trial of Niraparib in Platinum-Sensitive Castration-Resistant Prostate Cancer With DNA Repair Defects
Abramson Cancer Center at Penn Medicine
NCT05676463 TERMINATED MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer
Thomas Jefferson University
NCT04443062 COMPLETED Lutetium-177-PSMA-617 in Oligo-metastatic Hormone Sensitive Prostate Cancer
Radboud University Medical Center
NCT06085729 SUSPENDED Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC)
M.D. Anderson Cancer Center
NCT06056791 COMPLETED Study of INKmune in Patients With mCRPC (CaRe Prostate)
Inmune Bio, Inc.
NCT03568188 COMPLETED Efficacy Evaluation of Focused HIFU (High Intensity Focused Ultrasound) Therapy in Patients With Localized Intermediate Risk Prostate Cancer
Hospices Civils de Lyon
NCT04461509 COMPLETED High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy
Alessandro D'Agnolo
NCT05000294 SUSPENDED Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
University of Florida
NCT03421782 COMPLETED Fatigue Interventions in Cancer (Exercise Intervention)
University of Utah
NCT06661902 COMPLETED Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial
University of Washington
NCT05730712 COMPLETED Pertuzumab, Trastuzumab, Hyaluronidase-zzxf and Enzalutamide for Treatment of Metastatic Castration-Resistant Prostate Cancer
Mayo Clinic
NCT04754425 TERMINATED Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer
M.D. Anderson Cancer Center
NCT05366842 TERMINATED Patient-Reported Erectile Recovery and Quality of Life Outcomes With Lyopreserved Placental Tissue Applied Directly Over Neurovascular Bundle During Nerve Sparing Radical Prostatectomy Versus Standard of Care
Johns Hopkins University
NCT03553602 TERMINATED HDR Brachytherapy, EBRT and STAD for the Treatment of Prostate Cancer
Loyola University
NCT04252625 TERMINATED Trial of Quercetin, Bromelain, Rye Flower Pollen & Papain on Reducing Severity of Radiation-Induced Prostatitis
University of Utah
NCT02772588 COMPLETED AASUR in High Risk Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT03338790 COMPLETED An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer
Bristol-Myers Squibb
NCT03565835 COMPLETED Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer
Montefiore Medical Center
NCT03503344 COMPLETED Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate Cancer
University of California, San Francisco
NCT03556904 COMPLETED FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE)
University of Michigan Rogel Cancer Center
NCT07333976 COMPLETED o Tadalafil for Prevention of Docetaxel-Induced Peripheral Neuropathy in Prostate Cancer
Tri-Service General Hospital
NCT04717154 COMPLETED Ipilimumab With Nivolumab for Molecular-selected Patients With Castration-resistant Prostate Cancer
Radboud University Medical Center
NCT06881823 WITHDRAWN Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC
Novartis Pharmaceuticals
NCT02985957 COMPLETED A Study of Nivolumab Plus Ipilimumab, Ipilimumab Alone, or Cabazitaxel in Men With Metastatic Castration-Resistant Prostate Cancer (CheckMate 650)
Bristol-Myers Squibb
NCT02854436 COMPLETED An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies
Janssen Research & Development, LLC
NCT04037358 COMPLETED RAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04631744 COMPLETED Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Weill Medical College of Cornell University
NCT05526248 COMPLETED A Study Called ARAMON to Learn to What Extent Does Study Treatment With Darolutamide Affects Testosterone Levels in Men With Prostate Cancer That Had Not Been Treated With Hormonal Therapy Compared to Treatment With Enzalutamide
Bayer
NCT04019327 COMPLETED A Study of the Drugs Talazoparib and Temozolomide in Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT02772562 TERMINATED Adjuvant PROSTVAC-V/F in Subjects at High Risk for Relapse After Radical Prostatectomy
Medical University of South Carolina
NCT04176497 TERMINATED PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study
UNC Lineberger Comprehensive Cancer Center
NCT03007732 COMPLETED Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT
David Oh
NCT03496805 COMPLETED Effects of Muscadine Grape Extract in Men With Prostate Cancer on Androgen Deprivation Therapy
Wake Forest University Health Sciences
NCT04635059 TERMINATED Pacritinib for Biochemical Relapse After Definitive Treatment for Prostate Cancer
Medical College of Wisconsin
NCT05256381 TERMINATED A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors
SOTIO Biotech AG
NCT05617040 TERMINATED Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer
Barinthus Biotherapeutics
NCT03480646 COMPLETED ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate Cancer
Constellation Pharmaceuticals
NCT04019964 COMPLETED Nivolumab in Biochemically Recurrent dMMR Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06060587 WITHDRAWN Randomized Phase II Study of ADT + Abiraterone vs ADT + Docetaxel + Abiraterone
Northwestern University
NCT06434909 COMPLETED CYTALUX™for the Intraoperative Imaging of Prostate Cancer
Indiana University
NCT03910660 COMPLETED A Trial of BXCL701 and Pembrolizumab in Patients With mCRPC Either Small Cell Neuroendocrine Prostate Cancer or Adenocarcinoma Phenotype.
BioXcel Therapeutics Inc
NCT06392841 WITHDRAWN Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations
Qian Qin
NCT03069937 COMPLETED Phase II Study of Docetaxel Before Degarelix in Patients With Newly Diagnosed Metastatic Prostate Cancer.
Medical University of South Carolina
NCT03939689 COMPLETED I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW).
Progenics Pharmaceuticals, Inc.
NCT04631601 TERMINATED Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)
Amgen
NCT03652493 COMPLETED Trial Evaluating the Efficacy of CARBOPLATIN in Metastatic Prostate Cancer With Gene Alterations in the Homologous Recombination Pathway
Centre Francois Baclesse
NCT04616547 TERMINATED Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones
National Cancer Institute (NCI)
NCT05046782 WITHDRAWN Abbreviated Biparametric MRI (RSI + T2WI) for Prostate Cancer Detection: Correlation With Histopathology
M.D. Anderson Cancer Center
NCT03493945 COMPLETED Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)
National Cancer Institute (NCI)
NCT03516812 COMPLETED Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer
University of Washington
NCT06527690 WITHDRAWN Race Impact on Efficacy of Niraparib Plus Abiraterone Acetate and Prednisone in Patients With Homologous Repair Deficient Castration-resistant Prostate Cancer
Latin American Cooperative Oncology Group
NCT06528210 WITHDRAWN Pembrolizumab With Androgen Deprivation Therapy and Radiotherapy for the Treatment of Patients With High Risk Localized Prostate Cancer
OHSU Knight Cancer Institute
NCT03716739 COMPLETED Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency
Dana-Farber Cancer Institute
NCT04158245 COMPLETED 18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies
Tulane University
NCT05081193 COMPLETED Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05445609 SUSPENDED Vidutolimod (CMP-001) in Combination With Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer
Emory University
NCT05588609 TERMINATED Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers
Merus B.V.
NCT03098836 COMPLETED Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer
Daniel George, MD
NCT05230251 COMPLETED Radioligand fOr locAl raDiorecurrent proStaTe cancER
Glenn Bauman
NCT03843918 TERMINATED A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Prostate Cancer
Laekna Limited
NCT03458247 COMPLETED Study of Dose Escalation of Abiraterone Actetate in Prostate Cancer
Assistance Publique - Hôpitaux de Paris
NCT05946603 COMPLETED IS-002 Phase 2 Prostate Cancer Study
Intuitive Surgical
NCT03570827 COMPLETED Hypofractionated Radiation Therapy for Treating Prostate Cancer High-Risk Features Following Radical Prostatectomy
Mayo Clinic
NCT05633160 TERMINATED 64Cu-SAR-BBN and 67CU SAR-BBN for Identification and Treatment of Gastrin Releasing Peptide Receptor (GRPR)-Expressing Metastatic Castrate Resistant Prostate Cancer in Patients Who Are Ineligible for Therapy With 177Lu-PSMA-617 (COMBAT)
Clarity Pharmaceuticals Ltd
NCT02874014 COMPLETED Hypofractionation Proton Beam Therapy With Concurrent Treatment of Prostate and Pelvic Nodes for Prostate Cancer
Mayo Clinic
NCT04391556 COMPLETED Interest of PET-PSMA Imaging Potentialised by Androgen Blockade in Localized Prostatic Adenocarcinoma
Centre Leon Berard
NCT04336943 TERMINATED Durvalumab and Olaparib for the Treatment of Prostate Cancer in Men Predicted to Have a High Neoantigen Load
University of Washington
NCT03568656 COMPLETED Study to Evaluate CCS1477 in Advanced Tumours
CellCentric Ltd.
NCT03298087 COMPLETED Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer
VA Office of Research and Development
NCT03729596 TERMINATED MGC018 With or Without MGA012 in Advanced Solid Tumors
MacroGenics
NCT02769962 COMPLETED Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer
National Cancer Institute (NCI)
NCT03606837 COMPLETED 68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Intermediate Risk Prostate Cancer Imaging
University Hospital, Bordeaux
NCT04381832 COMPLETED Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer
Arcus Biosciences, Inc.
NCT03448458 COMPLETED Gallium Ga 68-DOTATATE PET/CT in Diagnosing Patients With Metastatic Castration Resistant Prostate Cancer
Emory University
NCT05005728 COMPLETED XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer
Xencor, Inc.
NCT02430480 COMPLETED Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate Cancer
National Cancer Institute (NCI)
NCT03432897 TERMINATED BrUOG 337: Olaparib Prior to Radical Prostatectomy For Advanced Prostate Cancer Defects in DNA Repair Genes
Brown University
NCT04569461 WITHDRAWN Trimodality Approach of Low Dose iOnizing Radiation With or Without Neoadjuvant Pembrolizumab and Prostatectomy for Men With Intermediate/High Risk Prostate Cancer (TALON)
Duke University
NCT04621500 COMPLETED Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Among Veterans
Medical University of South Carolina
NCT04886986 SUSPENDED Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer
Weill Medical College of Cornell University
NCT03815942 TERMINATED VAccination in Early and ADvanced Prostate caNCEr
University of Oxford
NCT04102124 TERMINATED A Study of SHR3680 in Combination With SHR3162 in the Treatment of mCRPC
Jiangsu HengRui Medicine Co., Ltd.
NCT05171387 COMPLETED Darolutamide + Androgen Deprivation Therapy (ADT) in Chinese Men With High Risk, Nonmetastatic Prostate Cancer
Bayer
NCT03315871 COMPLETED Combination Immunotherapy in Biochemically Recurrent Prostate Cancer
National Cancer Institute (NCI)
NCT07024030 COMPLETED Safety and Efficacy Trial of a Targeted PSMA Fluorescent Contrast Agent (DGPR1008) for Intraoperative Imaging of Prostate Cancer
Haitao Niu, MD
NCT02903368 COMPLETED Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy
Dana-Farber Cancer Institute
NCT05253053 COMPLETED To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT03442556 TERMINATED Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency
University of Washington
NCT05712174 TERMINATED A Study of [18]F-PSMA-1007 in Patients With Known or Suspected Metastatic Prostate Cancer
AHS Cancer Control Alberta
NCT03712371 TERMINATED Study of Chitosan for Pharmacologic Manipulation of AGE Levels in Prostate Cancer Patients
Medical University of South Carolina
NCT05169684 TERMINATED A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer
Bristol-Myers Squibb
NCT06312670 COMPLETED Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer
Pedro Barata, MD, MSc
NCT04068896 COMPLETED Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
NGM Biopharmaceuticals, Inc
NCT06389695 COMPLETED Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM032 in Patients
Norroy Bioscience Co., LTD
NCT04390880 COMPLETED 18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer
VA Greater Los Angeles Healthcare System
NCT04926181 TERMINATED Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer
Rahul Aggarwal
NCT02788773 COMPLETED Durvalumab With or Without Tremelimumab in Metastatic Castration Resistant Prostate Cancer
Canadian Cancer Trials Group
NCT04332744 COMPLETED Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First)
MedSIR
NCT02278185 COMPLETED Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer
University of Colorado, Denver
NCT02946996 TERMINATED Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Medical University of South Carolina
NCT03570619 COMPLETED Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations
University of Michigan Rogel Cancer Center
NCT05177770 TERMINATED Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer
Coherus Oncology, Inc.
NCT02967458 COMPLETED Detection of High Grade Prostate Cancer With Subharmonic Ultrasound Imaging, A Pilot Study
Thomas Jefferson University
NCT03304418 COMPLETED Radium-223 and Radiotherapy in Hormone-Naïve Men With Oligometastatic Prostate Cancer to Bone
University of Utah
NCT04523207 COMPLETED A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases
Janssen Research & Development, LLC
NCT03581500 WITHDRAWN Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Predicting Treatment Response in Patients With Prostate Cancer
M.D. Anderson Cancer Center
NCT05815316 WITHDRAWN 18F-PSMA PET/MRI for the Diagnosis of Clinically Significant Prostate Cancer
IRCCS San Raffaele
NCT03764540 TERMINATED Docetaxel Versus Cabazitaxel Post Abiraterone or Enzalutamide
Centre hospitalier de l'Université de Montréal (CHUM)
NCT04011410 COMPLETED Hydroxychloroquine to Increase Tumor Suppressor PAR-4 Levels in Oligometastatic Prostate Cancer
Patrick Hensley
NCT04556617 TERMINATED PLX2853 in Combination With Abiraterone Acetate and Prednisone and in Combination With Olaparib in Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Opna Bio LLC
NCT03654638 COMPLETED Soy Bread Diet in Improving Immune Function in Participants With Prostate Cancer
Ohio State University Comprehensive Cancer Center
NCT04383210 TERMINATED Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Elevation Oncology
NCT03888612 COMPLETED Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer
Arvinas Inc.
NCT03093428 COMPLETED Study Evaluating the Addition of Pembrolizumab to Radium-223 in mCRPC
Dana-Farber Cancer Institute
NCT05137067 COMPLETED A Novel Approach for Alleviating the Side Effects of Chemotherapeutic Agents.
Optimal Health Research
NCT03655886 COMPLETED Cytoreductive Prostatectomy Versus Cytoreductive Prostate Irradiation As a Local Treatment Option for Metastatic Prostate Cancer: a Multicentric Feasibility Trial
University Hospital, Ghent
NCT04382898 TERMINATED PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy)
BioNTech SE
NCT04298983 TERMINATED Abemaciclib in Combination With Androgen Deprivation Therapy for Locally Advanced Prostate Cancer
University of Alabama at Birmingham
NCT02649790 COMPLETED Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications
Karyopharm Therapeutics Inc
NCT06257758 TERMINATED A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors
Valerio Therapeutics
NCT04832958 COMPLETED Imaging Guided Surgery to Improve the Detection of Lymph Node Metastases in Prostate Cancer Patients
IRCCS San Raffaele
NCT06643494 SUSPENDED Elimination of Prostate Cancer Treatment Side Effects Using a Nutraceutical
Optimal Health Research
NCT04032704 TERMINATED A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors
Seagen Inc.
NCT05075577 TERMINATED EPI-7386 in Combination with Enzalutamide Compared with Enzalutamide Alone in Subjects with MCRPC
ESSA Pharmaceuticals
NCT05501548 TERMINATED Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04869488 COMPLETED A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT03643107 COMPLETED Irofulven in AR-targeted and Docetaxel-Pretreated mCRPC Patients With Drug Response Predictor (DRP®)
Allarity Therapeutics
NCT04487847 COMPLETED 18F-PSMA-1007 PET Imaging to Detect Primary Prostate Cancer
Radboud University Medical Center
NCT03518606 COMPLETED Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours
UNICANCER
NCT06398470 COMPLETED Study to Evaluate a New Method to Detect Residual Tumours During Surgery for Prostate Cancer Using Confocal Microscopy
University College, London
NCT04775602 COMPLETED Experimental Study to Evaluate the Impact of 18 Fluoro-PSMA (18F-PSMA) PET / CT in the Management of Patients with Prostate Cancer.
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT02643667 COMPLETED Ibrutinib as Neoadjuvant Therapy in Localized Prostate Cancer
Washington University School of Medicine
NCT03454750 COMPLETED Radiometabolic Therapy (RMT) With 177Lu PSMA 617 in Advanced Castration Resistant Prostate Cancer (CRPC)
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT04951492 TERMINATED Olaparib for the Treatment of Castration Resistant Prostate Adenocarcinoma
University of Washington
NCT05146973 COMPLETED External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)
Telix Pharmaceuticals (Innovations) Pty Limited
NCT05917470 TERMINATED A Clinical Study of ONCT-534 in Subjects With Metastatic Castration-resistant Prostate Cancer.
Oncternal Therapeutics, Inc
NCT03002220 COMPLETED Trial of Rad-223 Activity in Asymptomatic Patients With mCRPC While on Abiraterone or Enzalutamide Besides AR-V7 Status
MedSIR
NCT02362464 COMPLETED Long-Term TARP Vaccination Using a Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139
National Cancer Institute (NCI)
NCT04179864 TERMINATED A Study of Tazemetostat With Enzalutamide or Abiraterone/Prednisone in Participants With Advanced Prostate Cancer
Epizyme, Inc.
NCT02799745 COMPLETED A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance
Astellas Pharma Global Development, Inc.
NCT04992026 COMPLETED The Efficacy and Safety of Prostatectomy for Castration-Naive Oligometastatic Prostate Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT03707184 COMPLETED Fluciclovine F18 PET/CT Imaging in Assessing Hormone-Naive Men With Prostate Cancer That Has Spread to the Bone
University of Utah
NCT02787005 COMPLETED Study of Pembrolizumab (MK-3475) in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)(MK-3475-199/KEYNOTE-199)
Merck Sharp & Dohme LLC
NCT03248570 COMPLETED Pembrolizumab in Metastatic Castration Resistant Prostate Cancer (mCRPC) With or Without DNA Damage Repair Defects
University of California, San Francisco
NCT03414034 COMPLETED Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer
Cardiff Oncology
NCT06218667 WITHDRAWN A Study of Copanlisib in Combination with Degarelix in People with Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT06472531 COMPLETED A Study of PET/CT Imaging Using INR101 Injection in Healthy Male Subjects and Patients With Suspected Prostate Cancer
Yunhe Pharmaceutical (Tianjin) Co., Ltd
NCT03413995 COMPLETED Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05655715 COMPLETED Checkpoint Inhibitors and SBRT for MCRPC
Herlev and Gentofte Hospital
NCT03204812 COMPLETED Durvalumab and Tremelimumab in Treating Chemotherapy Naive Patients With Metastatic Castration-Resistant Prostate Cancer
M.D. Anderson Cancer Center
NCT04060394 COMPLETED Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC
Laekna Limited
NCT03207867 TERMINATED A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma
Novartis Pharmaceuticals
NCT03177187 TERMINATED Combination Study of AZD5069 and Enzalutamide.
Institute of Cancer Research, United Kingdom
NCT03869762 TERMINATED Denosumab in Combination With Enzalutamide in Progressive Metastatic Castrate-resistant Prostate Cancer and Bone Metastases.
Cancer Trials Ireland
NCT04207255 COMPLETED Addition of Opaganib to Androgen Antagonists in Patients With mCRPC
Medical University of South Carolina
NCT04733768 COMPLETED 18F-PSMA-1007 PET/CT Imaging in Patients with Biochemically Recurrent or High-risk Prostate Cancer
University of Alberta
NCT06329830 WITHDRAWN 177Lu-PSMA, Niraparib/AA Plus Prednisone for Prostate Cancer
Baptist Health South Florida
NCT05700669 COMPLETED Study to Assess Safety and Efficacy of AsiDNA in Combination with Olaparib in Participants with Recurrent Solid Tumors
Valerio Therapeutics
NCT02825628 COMPLETED Study of ODX (Osteodex) in Metastatic Castration Resistant Prostate Cancer (CRPC)
DexTech Medical AB
NCT03473925 COMPLETED Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034)
Merck Sharp & Dohme LLC
NCT02431676 COMPLETED Survivorship Promotion In Reducing IGF-1 Trial
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06065059 TERMINATED Study to Evaluate TNG348 Alone and With a PARP Inhibitor in Patients With BRCA 1/2 Mutant or HRD+ Solid Tumors
Tango Therapeutics, Inc.
NCT02649855 COMPLETED Docetaxel and PROSTVAC for Metastatic Castration-Sensitive Prostate Cancer
National Cancer Institute (NCI)
NCT03336983 COMPLETED Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
NCT04159896 TERMINATED ESK981 and Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer
Barbara Ann Karmanos Cancer Institute
NCT03770455 TERMINATED Avelumab Plus 2nd-generation ADT in African American Subjects With mCRPC
Jodi Layton, MD
NCT04408924 COMPLETED Abemaciclib (LY2835219) in Men With Heavily Treated Metastatic Castration-Resistant Prostate Cancer
Eli Lilly and Company
NCT03690141 TERMINATED An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer
Effector Therapeutics
NCT04957290 TERMINATED A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors
Noxopharm Limited
NCT05553639 TERMINATED HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer
Hookipa Biotech GmbH
NCT05141760 COMPLETED 18F-PSMA PET and MRI in the Primary Staging of Prostate Cancer Patients
University of Alberta
NCT02933255 COMPLETED PROSTVAC in Combination With Nivolumab in Men With Prostate Cancer
National Cancer Institute (NCI)
NCT05679193 COMPLETED Perioperative Propranolol During Prostatectomy to Decrease Cancer Recurrence
Oslo University Hospital
NCT02555189 COMPLETED Enzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma Expression
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT03035357 WITHDRAWN Neoadjuvant Listeria or Daratumumab in Prostate Cancer
M.D. Anderson Cancer Center
NCT03572387 COMPLETED A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment
Icahn School of Medicine at Mount Sinai
NCT04742959 COMPLETED Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT04458311 TERMINATED Abiraterone Acetate in Combination With Tildrakizumab
Institute of Cancer Research, United Kingdom
NCT04028388 COMPLETED ModraDoc006/r vs Docetaxel IV in Metastatic Prostate Cancer
Modra Pharmaceuticals
NCT04089553 COMPLETED An Open-label, Phase II Study of AZD4635 in Patients With Prostate Cancer
AstraZeneca
NCT03810105 TERMINATED A Study of Olaparib and Durvalumab in Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT03148795 COMPLETED A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate Cancer
Pfizer
NCT02325557 COMPLETED ADXS31-142 Alone and in Combination With Pembrolizumab (MK-3475) in Participants With Previously Treated Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Advaxis, Inc.
NCT05445882 WITHDRAWN N-803 Alone or in Combination With BN-Brachyury Vaccine or Bintrafusp Alfa (M7824) for Participants With Castration Resistant Prostate Cancer
National Cancer Institute (NCI)
NCT04243941 WITHDRAWN PSMA-PET/MRI Low- and Intermediate-Risk Prostate Cancer
UNC Lineberger Comprehensive Cancer Center
NCT03311555 COMPLETED A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR)
Andrew J. Armstrong, MD
NCT05361915 SUSPENDED Study to Assess Abivertinib in Combination With Abiraterone in Metastatic Castration Resistant Prostate Cancer
Sorrento Therapeutics, Inc.
NCT05574712 WITHDRAWN A Neoadjuvant Study of Abiraterone Acetate, Leuprolide Acetate, and Belzutifan in Men With Regional Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02933801 TERMINATED ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents.
Swiss Cancer Institute
NCT03533946 TERMINATED Rucaparib in Nonmetastatic prOstAte With BRCAness
University of Utah
NCT05034562 WITHDRAWN Gallium-68 PSMA-11 PET in Participants With Prostate Cancer
M.D. Anderson Cancer Center
NCT03554317 COMPLETED COMbination of Bipolar Androgen Therapy and Nivolumab
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04727736 TERMINATED 18F-DCFPyL Positron Emission Tomography (PET) in Intermediate or High Risk Prostate Cancer
Ashok Muthukrishnan
NCT03577028 TERMINATED Study of HPN424 in Patients With Advanced Prostate Cancer
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT03899467 COMPLETED The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC
Suzhou Kintor Pharmaceutical Inc,
NCT02903160 COMPLETED Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)
Icahn School of Medicine at Mount Sinai
NCT03651271 COMPLETED Nivolumab With or Without Ipilimumab in Advanced Metastatic Cancer
Parker Institute for Cancer Immunotherapy
NCT04264208 TERMINATED HDR Brachytherapy 68-Ga-RM2 PET, 68-Ga-PSMA-11 PET &Multi Parametric MRI in Prostate Cancer
Andrei Iagaru
NCT03878823 COMPLETED Safety and Pharmacokinetics of ODM-209
Orion Corporation, Orion Pharma
NCT02543255 COMPLETED Anti-Androgens and Cabazitaxel in Defining Complete Response in Prostatectomy (ACDC Trial)
University Health Network, Toronto
NCT03698370 COMPLETED Gallium Ga 68 DOTA-NeoBOMB1 and Gallium Ga 68 PSMA-R2 PET/MRI in Diagnosing Participants With Recurrent Prostate Cancer
Andrei Iagaru
NCT03949517 COMPLETED 68-Ga PSMA 11 PET/MRI and 68-Ga RM2 PET/MRI for Evaluation of Prostate Cancer Response to HIFU Therapy
Andrei Iagaru
NCT03809078 COMPLETED 68Ga PSMA 11 PET/MRI and 68Ga RM2 PET/MRI for Biopsy Guidance in Patients With Suspected Prostate Cancer
Andrei Iagaru
NCT03837353 TERMINATED A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1
NYU Langone Health
NCT03113617 COMPLETED 68Ga-RM2 PET/CT in Detecting Regional Nodal and Distant Metastases in Patients With Intermediate or High-Risk Prostate Cancer
Andrei Iagaru
NCT03513211 COMPLETED Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer
St Vincent's Hospital, Sydney
NCT04737109 TERMINATED Neoadjuvant Androgen Deprivation, Darolutamide, and Ipatasertib in Men With Localized, High Risk Prostate Cancer
David VanderWeele
NCT05405439 TERMINATED To Evaluate the Efficacy of TQB3823 Combined With Abiraterone and Prednisone in Metastatic Castration-resistant Prostate Cancer Patientsprednisone Acetate Tablets in Patients With Metastatic Castration-resistant Prostate Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT03396874 COMPLETED Gallium-68 PSMA-11 PET in Patients With Biochemical Recurrence
University of Michigan
NCT03649841 TERMINATED Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer
University of Washington
NCT03830164 COMPLETED Pentoxifylline, Atorvastatin, and Vitamin E in Treating Patients With Erectile Dysfunction After Radiation Therapy for Prostate Cancer
M.D. Anderson Cancer Center
NCT03999515 TERMINATED Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate Cancer
University of Washington
NCT05613842 COMPLETED Copper-64 SAR Bombesin in PSMA Negative Prostate Cancer (BOP)
St Vincent's Hospital, Sydney
NCT03752099 TERMINATED To Evaluate Safety and Tolerability of VERU-111 in Men With Advanced Metastatic Castration Resistant Prostate Cancer
Veru Inc.
NCT05516329 COMPLETED Study of 18F-Thretide PET/CT in Patients With Prostate Cancer
First Affiliated Hospital of Fujian Medical University
NCT04614363 COMPLETED 68 Ga-PSMA for High Risk Prostate Cancer
The Methodist Hospital Research Institute
NCT05489991 TERMINATED A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
Tceleron Therapeutics, Inc.
NCT04495179 COMPLETED A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.
AstraZeneca
NCT04936334 COMPLETED The Role of 68Ga-PSMA-11 PET (Prostate Specific Membrane Antigen) in Surgery Guidance in Prostate Cancer
Clinton Bahler
NCT03602079 COMPLETED Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Klus Pharma Inc.
NCT02499835 COMPLETED Vaccine Therapy and Pembrolizumab in Treating Patients With Hormone-Resistant, Metastatic Prostate Cancer
University of Wisconsin, Madison
NCT03658447 COMPLETED PRINCE (PSMA-lutetium Radionuclide Therapy and ImmuNotherapy in Prostate CancEr)
Peter MacCallum Cancer Centre, Australia
NCT04424641 TERMINATED A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors
Genmab
NCT02326805 COMPLETED PROSTVAC (PSA-TRICOM) in Preventing Disease Progression in Patients With Localized Prostate Cancer Undergoing Active Surveillance
National Cancer Institute (NCI)
NCT03456804 COMPLETED ESK981 in Treating Patients With Metastatic Castrate-Resistant Prostate Cancer
Barbara Ann Karmanos Cancer Institute
NCT04781374 WITHDRAWN Neratinib in Patients With Metastatic Castration-Resistant Prostate Cancer
Beth Israel Deaconess Medical Center
NCT05549778 COMPLETED Polaprezinc Treatment for Enzalutamide- or Abiraterone-resistant CRPC
Jiangnan University
NCT03735680 COMPLETED A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
OncoNano Medicine, Inc.
NCT02640534 TERMINATED Investigation of Metformin in Patients With Castration Resistant Prostate Cancer in Combination With Enzalutamide vs. Enzalutamide Alone
Swiss Cancer Institute
NCT04995978 WITHDRAWN Insulin Resistance and Androgen Deprivation Therapy
St. Louis University
NCT04676607 COMPLETED SHR7390 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT02952534 COMPLETED A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
pharmaand GmbH
NCT05582031 WITHDRAWN Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers
Translational Research in Oncology
NCT02516670 TERMINATED Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04843319 TERMINATED To Determine an Effective Dose of VERU-100 for the Treatment of Advanced Prostate Cancer
Veru Inc.
NCT04483414 WITHDRAWN 68Ga PSMA-11 PET/CT in Recurrent Prostate Cancer
Dana Mathews
NCT03429244 COMPLETED PSMA-PET for Biopsy and Treatment Guidance in Primary Prostate Cancer
Indiana University
NCT03437941 COMPLETED Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With mCRPC
Corcept Therapeutics
NCT03406858 COMPLETED Pembro and HER2Bi-Armed Activated T Cells in Treating Patients With Metastatic Castration Resistant Prostate Cancer
Barbara Ann Karmanos Cancer Institute
NCT02159950 COMPLETED Sipuleucel-T With or Without Tasquinimod in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Roswell Park Cancer Institute
NCT04085991 TERMINATED Two TraCer PositROn EmiSSion Tomography ComBination for Efficacy EstimatiOn of Prostate Specific Membrane Antigen Radioligand Therapy in Patients With Metastatic Prostate Cancer
Sir Mortimer B. Davis - Jewish General Hospital
NCT05806853 COMPLETED PET/MR for Prostate Cancer Restaging: a Phase II Prospective Monocentric Study
IRCCS San Raffaele
NCT02225704 COMPLETED Radium-223 in Combination With Enzalutamide
Cancer Trials Ireland
NCT03679260 COMPLETED Carbohydrate Restricted Diet Intervention for Men on Prostate Cancer Active Surveillance
Cedars-Sinai Medical Center
NCT04423913 TERMINATED Safety, Tolerability, Distribution & Dose Effect of Neoadjuvant Transarterial Chemoembolization With Doxorubicin in Prostate Cancer Patients Before Radical Prostatectomy
Centre Hospitalier Universitaire de Nīmes
NCT04179968 COMPLETED The Role of 68Gallium PSMA-11 in Enhancing Diagnosis of Primary and Metastatic Prostate Cancer
Dana Mathews
NCT03439033 TERMINATED Comparison Study of PET/CT or PET/MRI Imaging to Magnetic Resonance Imaging (MRI) Alone in Men With Prostate Cancer
Weill Medical College of Cornell University
NCT05705700 WITHDRAWN Biomarker Study of in Men With PSA Progression on Abi for CR or CS PC (Bio-STAMP)
Masonic Cancer Center, University of Minnesota
NCT03043807 COMPLETED A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02721979 TERMINATED Apalutamide in Treating Patients With Prostate Cancer Who Are in Active Surveillance
University of Washington
NCT02420652 TERMINATED Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy
Rutgers, The State University of New Jersey
NCT03982173 WITHDRAWN Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors
Gustave Roussy, Cancer Campus, Grand Paris
NCT02643303 COMPLETED A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers
Ludwig Institute for Cancer Research
NCT02680587 COMPLETED Stereotactic Body Radiation for Prostate Oligometastases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02598895 COMPLETED Docetaxel and Carboplatin in Treating Patients With Metastatic, Castration Resistant Prostate Cancer Containing Inactivated Genes in the BRCA 1/2 Pathway
University of Washington
NCT02649439 COMPLETED Prostvac in Patients With Biochemically Recurrent Prostate Cancer
National Cancer Institute (NCI)
NCT03434158 COMPLETED Olaparib Maintenance in Patients With MCRPC After Docetaxel Treatment Reaching Partial or Stable Response (IMANOL)
Spanish Oncology Genito-Urinary Group
NCT04928820 TERMINATED 68Ga-PSMA-11 PET/CT for the Diagnosis of Bone Metastases in Patients With Prostate Cancer and Biochemical Progression During Androgen Deprivation Therapy
Jonsson Comprehensive Cancer Center
NCT03709550 WITHDRAWN Enzalutamide and Decitabine in Treating Patients With Metastatic Castration Resistant Prostate Cancer
Roswell Park Cancer Institute
NCT02346526 COMPLETED A Biomarker Study of Standard-of-care Radium-223 Chloride for Metastatic Castration-resistant Prostate Cancer
Massachusetts General Hospital
NCT02766478 TERMINATED Genistein Supplementation to Mitigate Cardiometabolic Dysfunction in Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer
Emory University
NCT04685811 COMPLETED Evaluation of PSMA Antagonist Produced by Two Different Methods
Weill Medical College of Cornell University
NCT02789878 COMPLETED Neoadjuvant Androgen Deprivation Therapy Plus Abiraterone With or Without Apalutamide for High-Risk Prostate Cancer
Instituto do Cancer do Estado de São Paulo
NCT02203513 TERMINATED A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer
National Cancer Institute (NCI)
NCT02494921 COMPLETED LEE011 (Ribociclib) in Combination With Docetaxel Plus Prednisone in mCRPC
Rahul Aggarwal
NCT03279250 COMPLETED Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer
M.D. Anderson Cancer Center
NCT05191017 WITHDRAWN Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPC
Nuvation Bio Inc.
NCT02716974 COMPLETED A Study of Definitive Therapy to Treat Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04424654 COMPLETED Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Bipolar Androgen Therapy
Hospital Sirio-Libanes
NCT03531827 TERMINATED Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment
National Cancer Institute (NCI)
NCT02582749 TERMINATED Androgen Deprivation Therapy +/- Radium-223 Dichloride in Metastatic Prostate Cancer With Bone Metastases
Ajjai Alva, MD
NCT03964337 TERMINATED Immediate Prostatectomy vs. Cabozantinib Followed by Prostatectomy in Men With High-Risk Prostate Cancer
Duke University
NCT02770391 COMPLETED Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer
Case Comprehensive Cancer Center
NCT04090775 COMPLETED A Phase 2 Trial for Men With Metastatic Prostatic Adenocarcinoma
Rampart Health, L.L.C.
NCT03365791 COMPLETED PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies
Novartis Pharmaceuticals
NCT03373006 COMPLETED A Phase II Study to Evaluate Axumin PET/CT for Risk Stratification for Prostate Cancer
HALO Diagnostics
NCT03367819 TERMINATED Isatuximab in Combination With REGN2810 (Cemiplimab) in Patients With Advanced Malignancies
Sanofi
NCT04331717 WITHDRAWN Bariatric Arterial Embolization for Men Starting Hormones for Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02913131 TERMINATED Hyperpolarized C-13 Pyruvate as a Biomarker in Patients With Advanced Solid Tumor Malignancies
Rahul Aggarwal
NCT02815033 COMPLETED Imaging Staging and Response Prediction in Metastatic Hormono-Sensitive Prostate Cancer Patients Receiving Enzalutamide
The European Uro-Oncology Group
NCT02814968 COMPLETED PET/CT and WB MRI for Staging and Response in CRPC Patients Receiving Enzalutamide
The European Uro-Oncology Group
NCT02945813 TERMINATED SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy
Swiss Cancer Institute
NCT04221828 TERMINATED Trial of NanoPac Focal Therapy for Prostate Cancer
NanOlogy, LLC
NCT02362451 TERMINATED Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men With Stage D0 Prostate Cancer
National Cancer Institute (NCI)
NCT04862091 COMPLETED Comparative Study of Abiraterone Acetate Tablets (I) or ZYTIGA® in Patients With Metastatic Castration-resistant Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.
NCT03441464 TERMINATED Feasibility of the LUM Imaging System for Detection of Prostate Cancer
Lumicell, Inc.
NCT03101046 COMPLETED Treatment of Metastatic Castrate Resistant Prostate Cancer Patients According to Circulating Tumor Cells Kinetic
UNICANCER
NCT02601014 COMPLETED Biomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Expressing AR-V7
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02849990 COMPLETED A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomy
University of Washington
NCT03689582 TERMINATED Radiolabeled Gallium-68 (68Ga-PSMA) for PET/CT Imaging to Detect Prostate Cancer
University of Michigan Rogel Cancer Center
NCT03646162 COMPLETED Study of VERU-944 to Ameliorate Hot Flashes in Men With Advanced Prostate Cancer
Veru Inc.
NCT02711956 COMPLETED A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer
Zenith Epigenetics
NCT02648919 TERMINATED Clinical Study of Noni Extract in Men With Very Low Risk or Low Risk Prostate Cancer
University of Hawaii
NCT02506114 TERMINATED Neoadjuvant PROSTVAC-VF With or Without Ipilimumab for Prostate Cancer
Lawrence Fong
NCT02737332 COMPLETED A Study to Evaluate Serum Testosterone Levels in Patients With Metastatic Castration-Resistant Prostate Cancer
Sun Pharmaceutical Industries Limited
NCT02962284 COMPLETED One-year, Open Extension to Evaluate the Treatment of Patients With Castration-Resistant Prostate Cancer With YONSA™
Sun Pharmaceutical Industries Limited
NCT03712930 TERMINATED Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency
BeiGene
NCT04555343 COMPLETED Intravesical Antifibrinolytic for Patients With Hematuria and Clot Retention
Fraser Health
NCT03245736 COMPLETED Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.
Seagen Inc.
NCT03886493 TERMINATED Neoadjuvant Dupilumab in Men With Localized High-Risk Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04052204 TERMINATED Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors
Pfizer
NCT02508636 TERMINATED Trial of Radiotherapy With Leuprolide and Enzalutamide in High Risk Prostate Cancer
University of California, San Francisco
NCT02565901 TERMINATED Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
University of Washington
NCT04050215 COMPLETED 68GA-PSMA-11 PET/CT Scan in Impacting Treatment Strategies for Patients With Prostate Cancer
Jonsson Comprehensive Cancer Center
NCT02499497 COMPLETED A Selective Androgen Receptor Modulator for Symptom Management in Prostate Cancer
Dana-Farber Cancer Institute
NCT04020094 WITHDRAWN Perioperative Atezolizumab With MVA-BN-Brachyury and PROSTVAC For Intermediate-Risk And High-Risk Localized Prostate Cancer
University of Utah
NCT03062254 COMPLETED Metabolic Change in Prostate Cancer Bone Metastases on 68Ga-HBED-CC-PSMA PET/CT Following Radium-223 Therapy
Sir Mortimer B. Davis - Jewish General Hospital
NCT03545165 TERMINATED 177Lu-J591 and 177Lu-PSMA-617 Combination for mCRPC
Weill Medical College of Cornell University
NCT02985021 TERMINATED Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies
Seattle Institute for Biomedical and Clinical Research
NCT02463799 COMPLETED Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02867020 COMPLETED Study of Abiraterone Acetate Plus ADT Versus APALUTAMIDE Versus Abiraterone and APALUTAMIDE in Patients With Advanced Prostate Cancer With Non-castrate Testosterone Levels
Latin American Cooperative Oncology Group
NCT03361969 COMPLETED Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist.
Pantarhei Oncology B.V.
NCT02559115 COMPLETED 68Ga-RM2 for PET/CT of Gastrin Releasing Peptide Receptor (GRPr) Expression in Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT02407054 COMPLETED A Study of Enzalutamide and LY3023414 in Men With Prostate Cancer
Eli Lilly and Company
NCT02805894 TERMINATED NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate Adenocarcinoma
Nanobiotix
NCT02987829 COMPLETED Phase 1/2A Study of TRC253, an Androgen Receptor Antagonist, in Metastatic Castration-resistant Prostate Cancer Patients
Tracon Pharmaceuticals Inc.
NCT02497638 WITHDRAWN LIpitor and biGuanide to Androgen Delay Trial
University Health Network, Toronto
NCT02685267 TERMINATED Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate Cancer
Prostate Cancer Clinical Trials Consortium
NCT02552121 COMPLETED Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors
Seagen Inc.
NCT00737893 COMPLETED Erythropoietin to Enhance Recovery of Erectile Function in Men Following Radical Prostatectomy
Johns Hopkins University
NCT03042312 TERMINATED Lutetium-177 (Lu177) Prostate-Specific Antigen (PSMA)-Directed EndoRadiotherapy
Endocyte
NCT03572478 TERMINATED Rucaparib and Nivolumab in Patients With Prostate or Endometrial Cancer
University of Chicago
NCT03179410 COMPLETED PD-L1 Inhibition as ChecKpoint Immunotherapy for NeuroEndocrine Phenotype Prostate Cancer
Andrew J. Armstrong, MD
NCT03263780 COMPLETED High Resolution PET-MRI Before Prostate Cancer HIFU
Timothy J. Daskivich
NCT02628041 COMPLETED HDR Brachytherapy vs. LDR Brachytherapy Monotherapy in Localized Prostate Cancer
CHU de Quebec-Universite Laval
NCT03261336 TERMINATED Oral Calcitriol With Ketoconazole in CRPC
Donald Trump, MD
NCT03741712 TERMINATED A Study of SHR2554 Alone or in Combination With SHR3680 in the Treatment of mCRPC
Jiangsu HengRui Medicine Co., Ltd.
NCT03514836 TERMINATED A Phase I/II, Safety Clinical Trial of DCVAC/PCa and ONCOS-102 in Men With Metastatic Castration-resistant Prostate Cancer
SOTIO a.s.
NCT02844582 TERMINATED Cabazitaxel and Prednisone in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
University of California, Davis
NCT04585932 WITHDRAWN Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the Treatment of Biochemically Recurrent Prostate Cancer, RESTART Study
M.D. Anderson Cancer Center
NCT03418324 COMPLETED Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy
Cedars-Sinai Medical Center
NCT02611882 COMPLETED Evaluation of Gallium-68-HBED-CC-PSMA Imaging in Prostate Cancer Patients
Thomas Hope
NCT03348527 COMPLETED A Study to Evaluate the Safety, Tolerability and Efficacy of a Liproca® Depot Injection in Patients With Prostate Cancer
Lidds AB
NCT02607228 TERMINATED Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 (Alobresib) as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer
Gilead Sciences
NCT02397408 COMPLETED 11C- and 18F-Choline PET/MR Imaging for Prostate Cancer
University of California, San Francisco
NCT03173859 WITHDRAWN Efficacy of Rotations Between Abiraterone Acetate and Apalutamide in mCRPC Patients
University of Athens
NCT03490032 COMPLETED 68Ga-PSMA-R2 in Patients With Biochemical Relapse (BR) and Metastatic Prostate Cancer (mPCa)
Advanced Accelerator Applications
NCT02286921 COMPLETED Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03724253 TERMINATED [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)
Advanced Accelerator Applications
NCT02709889 TERMINATED Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
AbbVie
NCT03675451 COMPLETED PSMA Imaging of Localized Prostate Cancer
Weill Medical College of Cornell University
NCT03570476 TERMINATED Olaparib Before Surgery in Treating Participants With Localized Prostate Cancer
University of Washington
NCT03362359 COMPLETED Ga-68-PSMA-11 in High-risk Prostate Cancer
German Cancer Research Center
NCT03493997 COMPLETED Multicentre International STudy for the Prevention With Ialuril® of Radio-induced Cystitis (MISTIC)
Study Group for Urogenital Diseases, Italy
NCT03652298 TERMINATED Effects of a Neuroscience-based Technique on Cancer Patients Announced of a Palliative Disease Progression and Partners
Centre Oscar Lambret
NCT04272645 WITHDRAWN Abemaciclib With or Without Atezolizumab in Metastatic Castration Resistant Prostate Cancer
University of Michigan Rogel Cancer Center
NCT03827473 TERMINATED Docetaxel or Abiraterone Acetate With ADT in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer
University of Utah
NCT03617588 COMPLETED 68Ga-THP-PSMA PET/CT Imaging in High Risk Primary Prostate Cancer or Biochemical Recurrence of Prostate Cancer
Theragnostics Ltd
NCT03604757 COMPLETED 68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Prostate Cancer Imaging According to Various Metastatic Risks
University Hospital, Bordeaux
NCT03199872 COMPLETED RV001V, a RhoC Anticancer Vaccine, Against Metastasis From Solid Tumours
RhoVac APS
NCT02384382 COMPLETED A Positron Emission Tomography/Computed Tomography (PET/CT) Bone Imaging Study in Patients Receiving Enzalutamide for Castration-Resistant Prostate Cancer (CRPC)
Pfizer
NCT03093272 TERMINATED A Study of Docetaxel + ARN-509 in Castration-Resistant Prostate Cancer
Dana-Farber Cancer Institute
NCT03763851 TERMINATED Cannabis Oil and Radiation Therapy for the Management of Pain
Tetra Bio-Pharma
NCT03264456 COMPLETED Pretreatment Staging of High-Risk Prostate Cancer With 18F-Fluciclovine PET/MRI
University of Alabama at Birmingham
NCT02811809 WITHDRAWN Apalutamide Plus Intermittent Hormone Therapy Versus Intermittent Hormone Therapy Alone in Prostate Cancer
The University of Texas Health Science Center, Houston
NCT02349022 COMPLETED Comparison of PET With [89Zr]-Df-IAb2M and [111In]-Capromab Pendetide in the Detection of Prostate Cancer Pre-Prostatectomy
ImaginAb, Inc.
NCT02512458 COMPLETED Study of the Effect of Chemotherapy With Cabazitaxel on Prostate Cancer
Hellenic Cooperative Oncology Group
NCT02311764 TERMINATED Carboplatin in Castration-resistant Prostate Cancer
Aurelius Omlin
NCT02429193 COMPLETED Biomarkers of Androgen Response and Resistance In Evolution During a Rising PSA
University Health Network, Toronto
NCT02830880 COMPLETED FACBC Prostate Therapy Response
Emory University
NCT02344017 COMPLETED Safety and Pharmacokinetics of ODM-204 in Patients With Metastatic Castration-Resistant Prostate Cancer
Orion Corporation, Orion Pharma
NCT03365297 COMPLETED Therapeutics in Active Prostate Cancer Surveillance
CCTU- Cancer Theme
NCT02692976 COMPLETED Natural Dendritic Cells for Immunotherapy of Chemo-naive Metastatic Castration-resistant Prostate Cancer Patients
Radboud University Medical Center
NCT02758132 TERMINATED Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastases
University of Hawaii
NCT02538432 WITHDRAWN Phase II Trial of EP4 Receptor Antagonist, AAT-007 (RQ-07; CJ-023,423) in Advanced Solid Tumors
University of Maryland, Baltimore
NCT02964988 TERMINATED uPAR PET/CT in Radium-223-dichloride Treatment of Patients With Metastatic Castration-resistant Prostate Cancer
Rigshospitalet, Denmark
NCT02288936 COMPLETED Analyze the Predictive Value of Gene TMPRSS2-ETS in Response to Enzalutamide in Patients With Prostate Cancer
Spanish Oncology Genito-Urinary Group
NCT02710422 TERMINATED Miami Membrane for Potency (MMEP) Trial
University of Miami
NCT03384199 COMPLETED Dose Escalation Using Fiducial Markers in Image Guided Volumetric Modulated Arc Therapy to the Focal Lesion Micro Boost of Localized Prostate Cancer
Kasr El Aini Hospital
NCT02796898 COMPLETED Study of the Efficacy, Safety, and Pharmacokinetics of SM88 in Patients With Prostate Cancer
Tyme, Inc
NCT02379390 TERMINATED Cabazitaxel Versus the Switch to Alternative AR Targeted Therapy Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Primary Resistant Patients to Abiraterone or Enzalutamide
Sanofi
NCT03543670 COMPLETED Evaluation of Oncoxin-Viusid® in Prostate Cancer
Catalysis SL
NCT02744534 COMPLETED Targeted Fusion Biopsy of the Prostate
Emory University
NCT03573011 COMPLETED PSMA PET/CT for Prostate Cancer
University Hospital, Ghent
NCT02256111 COMPLETED EXTEND Exercise Trial
Duke University
NCT03081481 COMPLETED Intraprostatic PRX302 Injection to Treat Localised Prostate Cancer
Sophiris Bio Corp
NCT02584400 TERMINATED Tumor Hypoxia With HX4 PET in Several Diseases
Maastricht Radiation Oncology
NCT02507427 COMPLETED Monitoring and Mapping of Erectile Nerve During RALP (MMEN Study)
Seoul National University Hospital
NCT03001895 COMPLETED Correlation Between SUV on 18F-DCFPyL PET/CT and Gleason Score in Prostate Cancer
Sir Mortimer B. Davis - Jewish General Hospital
NCT02459912 TERMINATED Unilateral Nerve-Sparing Cryoablation for Low-Risk, Clinically Localized, Unilateral Prostate Cancer
NYU Langone Health
NCT02445976 COMPLETED Once-daily Oral Seviteronel in Patients With Castration-Resistant Prostate Cancer Progressing on Enzalutamide or Abiraterone.
Innocrin Pharmaceutical
NCT02409212 COMPLETED Exercise Training as a Novel Primary Therapy for Men With Localised Prostate Cancer
Sheffield Teaching Hospitals NHS Foundation Trust
NCT03147196 WITHDRAWN Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Mayo Clinic
NCT02853110 COMPLETED Hypofractionated Focal Lesion Ablative Microboost in prostatE Cancer
UMC Utrecht
NCT02560051 TERMINATED Hormone Therapy Plus Chemotherapy as Initial Treatment for Local Failures or Advanced Prostate Cancer
The University of Texas Health Science Center, Houston
NCT02494713 TERMINATED Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate Cancer
The University of Texas Health Science Center, Houston
NCT03343977 WITHDRAWN Toxicity & Pharmacokinetics of 2 & 3-weekly Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Peng Wang, MD PhD
NCT02252978 WITHDRAWN Ciprofloxacin Compared to Placebo in Diagnosing Prostate Cancer in Patients Undergoing Prostate Biopsy
Wake Forest University Health Sciences
NCT02796807 COMPLETED Correlation Between SUV on 68Ga-HBED-CC-PSMA and Gleason Score in Prostate Cancer
Sir Mortimer B. Davis - Jewish General Hospital
NCT02606123 TERMINATED Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic Castration-Resistant Prostate Cancer
ESSA Pharmaceuticals
NCT02966587 WITHDRAWN Durvalumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
University of Washington
NCT02793219 WITHDRAWN Provenge Followed by Docetaxel in Castration-Resistant Prostate Cancer
The University of Texas Health Science Center, Houston
NCT02793765 WITHDRAWN Docetaxel Followed by Provenge in Metastatic Prostate Cancer
The University of Texas Health Science Center, Houston
NCT02233608 COMPLETED Advanced Pelvic Floor Training Program for Prostate Cancer Surgery
University of Guelph-Humber
NCT02810886 WITHDRAWN Prospective Evaluation of 68Ga-PSMA PET-CT for Recurrence Detection of Prostate Cancer and Its Impact on Patient Management
Jules Bordet Institute
NCT02656615 TERMINATED Abiraterone-Rechallenge Study for CRPC Patients
Aurelius Omlin
NCT02483884 TERMINATED PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer
Life Molecular Imaging SA
NCT02381236 COMPLETED G-202 in the Neoadjuvant Setting Followed by Radical Prostatectomy in Patients With Prostate Cancer
GenSpera, Inc.
NCT02906605 WITHDRAWN A Study of the Clinical Activity and Safety of JNJ-64041809, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Apalutamide Versus Apalutamide in Subjects With Metastatic Castration-resistant Prostate Cancer
Janssen Research & Development, LLC
NCT02645591 WITHDRAWN Randomized AmnioFix Study During Radical Prostatectomy
M.D. Anderson Cancer Center
NCT02656563 WITHDRAWN Radium 223 Following Intermittent ADT
Canadian Urology Research Consortium
NCT02621190 WITHDRAWN Cabazitaxel in mCRPC Patients With AR-V7 Positive CTCs
Erasmus Medical Center
NCT02499848 COMPLETED Evaluate, Safety and Tolerability of Intraprostatic PRX302 Administration, Low to Intermediate Risk Prostate Cancer
Sophiris Bio Corp
NCT02678520 WITHDRAWN Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients
University of Kansas Medical Center
NCT02378870 TERMINATED A Phase IIb Study to Evaluate Efficacy and Tolerability of ODX (Osteodex) in Metastatic CRPC
DexTech Medical AB
NCT01530984 WITHDRAWN Ipilimumab and GMCSF Immunotherapy for Prostate Cancer
Lawrence Fong
NCT02338700 COMPLETED Safety and Efficacy Study of Mix Vaccine in Prostate Carcinoma Patient
Fuda Cancer Hospital, Guangzhou
NCT02424513 WITHDRAWN A Study of Positron Emission Tomography (PET) With [89]Zr-Df-IAb2M in Patients With High-risk Prostate Cancer
ImaginAb, Inc.