507 active
/
892 total (since 2015)
226
Phase 1 Active
435 total
324
Phase 2 Active
551 total
40
Phase 3 Active
62 total
6
Phase 4 Active
12 total
Top Sponsors (Industry)
Sorted by active Active Done Failed
Eli Lilly 3 6 3
Hansoh BioMedical R&D Company 3 0 0
Philogen S.p.A. 3 0 0
Pfizer 2 1 4
Amgen 2 0 0
USWM CT, LLC 2 0 0
Lantheus Medical Imaging 2 0 0
Inhibrx Biosciences, Inc 2 0 0
Jazz Pharmaceuticals 2 0 0
GI Innovation, Inc. 2 0 0
Novartis 1 2 1
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 1 0 3
MacroGenics 1 1 1
Takara Bio Inc. 1 1 0
PharmaMar 1 1 0
NCT04214067 ACTIVE NOT RECRUITING
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer
National Cancer Institute (NCI) n=164
NCT05691478 RECRUITING
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
National Cancer Institute (NCI) n=1,122
NCT06422806 RECRUITING
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
National Cancer Institute (NCI) n=365
NCT03914612 ACTIVE NOT RECRUITING
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer
National Cancer Institute (NCI) n=813
NCT02567435 ACTIVE NOT RECRUITING
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
National Cancer Institute (NCI) n=325
NCT05566795 RECRUITING
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
Day One Biopharmaceuticals, Inc. n=400
NCT05235165 RECRUITING
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Children's Oncology Group n=62
NCT03016819 RECRUITING
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
Advenchen Laboratories, LLC n=325
NCT05304585 RECRUITING
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
Children's Oncology Group n=205
NCT07174427 RECRUITING
Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma
Takara Bio Inc. n=5
NCT06820957 ACTIVE NOT RECRUITING
Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body
Children's Oncology Group n=437
NCT04994132 ACTIVE NOT RECRUITING
A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma
Children's Oncology Group n=118
NCT05095376 ACTIVE NOT RECRUITING
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
NRG Oncology n=265
NCT06088290 RECRUITING
Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)
PharmaMar n=450
NCT04307277 RECRUITING
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma
Institut Claudius Regaud n=600
NCT06127407 RECRUITING
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen
Servier Bio-Innovation LLC n=136
NCT05432791 ACTIVE NOT RECRUITING
Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
National Cancer Institute (NCI) n=73
NCT05411237 NOT YET RECRUITING
Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma
AIDS Malignancy Consortium n=130
NCT03651206 RECRUITING
Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib
ARCAGY/ GINECO GROUP n=138
NCT03422198 RECRUITING
Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer
University of Utah n=188
NCT03784014 ACTIVE NOT RECRUITING
Molecular Profiling of Advanced Soft-tissue Sarcomas
Institut National de la Santé Et de la Recherche Médicale, France n=603
NCT06988475 RECRUITING
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
Cancer Research UK n=30
NCT05646316 RECRUITING
Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NRG Oncology n=428
NCT03805022 RECRUITING
Benefit of Intensified Peri-operative Chemotherapy Within High-risk CINSARC Patients With Resectable Soft-tissue Sarcomas
Institut Bergonié n=351
NCT06263231 ACTIVE NOT RECRUITING
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Intensity Therapeutics, Inc. n=333
NCT05712694 RECRUITING
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
Polaris Group n=300
NCT06332274 RECRUITING
tislelizUMaB in canceR Patients With molEcuLar residuaL Disease
Gustave Roussy, Cancer Campus, Grand Paris n=717
NCT06935409 NOT YET RECRUITING
Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure
Hansoh BioMedical R&D Company n=117
NCT04757337 RECRUITING
Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients
UNICANCER n=214
NCT02413736 ACTIVE NOT RECRUITING
Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST
Heikki Joensuu n=255
NCT06836492 RECRUITING
A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors.
Yizhuo Zhang n=300
NCT04031677 RECRUITING
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC n=250
NCT04967521 ACTIVE NOT RECRUITING
SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma
Sarcoma Alliance for Research through Collaboration n=108
NCT06669013 RECRUITING
Chemo-immunotherapy in Patients Under 18 Years of Age With Bone and Soft Tissue Sarcomas
N.N. Petrov National Medical Research Center of Oncology n=40
NCT06480396 NOT YET RECRUITING
High Versus Lower Intensity Surveillance Following Resection of Retroperitoneal Sarcoma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano n=584
NCT04650984 RECRUITING
A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma
Philogen S.p.A. n=102
NCT05057130 RECRUITING
Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors
Blokhin's Russian Cancer Research Center n=50
NCT02565498 ACTIVE NOT RECRUITING
Preoperative vs Postoperative IMRT for Extremity/Truncal STS
Mount Sinai Hospital, Canada n=210
NCT05328258 RECRUITING
Use of GnRHa During Chemotherapy for Fertility Protection
Kenny Rodriguez-Wallberg n=500
NCT04396860 COMPLETED
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
National Cancer Institute (NCI) n=159
NCT05218499 COMPLETED
Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma
Boehringer Ingelheim n=400
NCT06058793 COMPLETED
Brightline-4: A Study to Test How Well Brigimadlin is Tolerated by People With a Type of Cancer Called Dedifferentiated Liposarcoma
Boehringer Ingelheim n=138
NCT02451943 COMPLETED
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company n=509
NCT05269355 TERMINATED
A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)
PTC Therapeutics n=359
NCT04979442 TERMINATED
Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma
Rain Oncology Inc n=175
NCT06370871 WITHDRAWN
Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue Sarcoma
Boehringer Ingelheim
NCT04656262 TERMINATED
Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients
Istituto Oncologico Veneto IRCCS n=79
NCT04780464 TERMINATED
A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC n=14
NCT05024253 COMPLETED
Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.
Children's Cancer Hospital Egypt 57357 n=48
NCT02573324 COMPLETED
A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
AbbVie n=691
NCT03495921 TERMINATED
A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide
Gradalis, Inc. n=32
NCT02997358 COMPLETED
Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma
Gustave Roussy, Cancer Campus, Grand Paris n=150
NCT02379845 COMPLETED
NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall
Nanobiotix n=180
NCT02929394 TERMINATED
Trabectedin Maintenance Post 1st-line in STS
European Organisation for Research and Treatment of Cancer - EORTC n=13
NCT02979899 COMPLETED
Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma
Tracon Pharmaceuticals Inc. n=128
NCT03520959 TERMINATED
A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) n=1
NCT03773510 WITHDRAWN
Study on Leiomyosarcoma, Liposarcomas and Synovial Sarcoma With Trabectedin
Italian Sarcoma Group
NCT02672527 COMPLETED
Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma
Gustave Roussy, Cancer Campus, Grand Paris n=103
NCT02711007 COMPLETED
Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy
GUO WEI n=37
NCT07308886 NOT YET RECRUITING
Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)
National Cancer Institute (NCI)
NCT06498648 RECRUITING
Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT02834013 ACTIVE NOT RECRUITING
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
National Cancer Institute (NCI)
NCT05333458 RECRUITING
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial
National Cancer Institute (NCI)
NCT04595747 ACTIVE NOT RECRUITING
Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)
National Cancer Institute (NCI)
NCT05703854 RECRUITING
Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma
M.D. Anderson Cancer Center
NCT03213652 ACTIVE NOT RECRUITING
Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT02923778 ACTIVE NOT RECRUITING
Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery
National Cancer Institute (NCI)
NCT05286801 ACTIVE NOT RECRUITING
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors
National Cancer Institute (NCI)
NCT03210714 ACTIVE NOT RECRUITING
Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT02867592 ACTIVE NOT RECRUITING
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors
National Cancer Institute (NCI)
NCT07447050 RECRUITING
Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
University of California, Irvine
NCT06465199 RECRUITING
Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
Milton S. Hershey Medical Center
NCT06541262 RECRUITING
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
Milton S. Hershey Medical Center
NCT04771520 RECRUITING
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
M.D. Anderson Cancer Center
NCT06341712 ACTIVE NOT RECRUITING
Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma
Ipsen
NCT07193550 RECRUITING
A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)
M.D. Anderson Cancer Center
NCT05147558 ACTIVE NOT RECRUITING
A Study of Pembrolizumab With Lenvatinib in Women With Advanced Uterine Carcinosarcoma
Memorial Sloan Kettering Cancer Center
NCT07291297 NOT YET RECRUITING
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Wake Forest University Health Sciences
NCT04417062 ACTIVE NOT RECRUITING
Olaparib With Ceralasertib in Recurrent Osteosarcoma
Dana-Farber Cancer Institute
NCT02455557 ACTIVE NOT RECRUITING
SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Roswell Park Cancer Institute
NCT07428993 NOT YET RECRUITING
Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma
St. Jude Children's Research Hospital
NCT04851119 RECRUITING
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Children's Oncology Group
NCT04458922 ACTIVE NOT RECRUITING
Testing Atezolizumab in People 2-17 Years Old With Clear Cell Sarcoma or Advanced Chondrosarcoma
National Cancer Institute (NCI)
NCT05969860 RECRUITING
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Mayo Clinic
NCT04288375 ACTIVE NOT RECRUITING
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs
Memorial Sloan Kettering Cancer Center
NCT04554914 RECRUITING
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
Pierre Fabre Medicament
NCT06709495 RECRUITING
Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas
David S Shulman, MD
NCT04339738 ACTIVE NOT RECRUITING
Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT07410676 RECRUITING
EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Essen Biotech
NCT05755113 RECRUITING
A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma
QBiotics Group Limited
NCT07283731 NOT YET RECRUITING
Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma
M.D. Anderson Cancer Center
NCT04698785 RECRUITING
Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients
Centre Leon Berard
NCT03624244 RECRUITING
Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)
Centre Leon Berard
NCT05253131 NOT YET RECRUITING
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
University of Alabama at Birmingham
NCT04577014 RECRUITING
Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
Memorial Sloan Kettering Cancer Center
NCT03155620 ACTIVE NOT RECRUITING
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
National Cancer Institute (NCI)
NCT05726383 RECRUITING
Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma
Hackensack Meridian Health
NCT03474094 ACTIVE NOT RECRUITING
Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy
Centre Leon Berard
NCT05180695 ACTIVE NOT RECRUITING
HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas
Centre Leon Berard
NCT06712433 NOT YET RECRUITING
Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO)
Adam Olson
NCT03851614 ACTIVE NOT RECRUITING
Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors
University Health Network, Toronto
NCT04901702 RECRUITING
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
St. Jude Children's Research Hospital
NCT04044768 ACTIVE NOT RECRUITING
Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
USWM CT, LLC
NCT06395103 RECRUITING
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Merck Sharp & Dohme LLC
NCT07125183 RECRUITING
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
University of Colorado, Denver
NCT03465592 RECRUITING
Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03598595 ACTIVE NOT RECRUITING
Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma
M.D. Anderson Cancer Center
NCT06843967 RECRUITING
A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT04562480 ACTIVE NOT RECRUITING
Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk
Mayo Clinic
NCT05734066 RECRUITING
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
Jazz Pharmaceuticals
NCT04332874 RECRUITING
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
Memorial Sloan Kettering Cancer Center
NCT04390737 RECRUITING
Evaluate the Safety and Clinical Activity of HH2853
Haihe Biopharma Co., Ltd.
NCT04195555 ACTIVE NOT RECRUITING
Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT05634369 RECRUITING
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
Nationwide Children's Hospital
NCT07173972 RECRUITING
Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.
Oslo University Hospital
NCT07007273 RECRUITING
Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT07169344 RECRUITING
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
Oslo University Hospital
NCT05109494 RECRUITING
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
University of Wisconsin, Madison
NCT04028063 RECRUITING
Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas
University of Colorado, Denver
NCT04784247 ACTIVE NOT RECRUITING
Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma
Memorial Sloan Kettering Cancer Center
NCT05694871 ACTIVE NOT RECRUITING
Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma
Alliance for Clinical Trials in Oncology
NCT06239272 RECRUITING
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
St. Jude Children's Research Hospital
NCT05797662 NOT YET RECRUITING
A Study of Propranolol to Treat Kaposi Sarcoma
AIDS Malignancy Consortium
NCT04189783 ACTIVE NOT RECRUITING
Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
M.D. Anderson Cancer Center
NCT04941274 RECRUITING
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
National Cancer Institute (NCI)
NCT05071209 ACTIVE NOT RECRUITING
Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT05084430 RECRUITING
Study of Pembrolizumab and M032 (NSC 733972)
University of Alabama at Birmingham
NCT07359053 RECRUITING
MAGNATE-S: Paclitaxel Polymer Micelles Combo in Advanced Sarcoma
Shanghai 6th People's Hospital
NCT07355855 NOT YET RECRUITING
A Clinical Study on the Efficacy and Safety of All-trans Retinoic Acid Combined With VAC Regimen in the Treatment of Intermediate-to-high-risk Rhabdomyosarcoma
Fudan University
NCT03921008 ACTIVE NOT RECRUITING
Induction Paclitaxel Followed by Concurrent Paclitaxel and Radiation Therapy for Cutaneous Angiosarcoma
Washington University School of Medicine
NCT06981637 RECRUITING
Pegylated Liposomal Doxorubicin (PLD) Versus Active Surveillance for Advanced Soft Tissue Sarcoma Patients Who Had Controlled Disease After Standard Anthracycline-based Treatment (MELODY)
National Health Research Institutes, Taiwan
NCT06710756 RECRUITING
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Perspective Therapeutics
NCT06660810 ACTIVE NOT RECRUITING
Neoadjuvant Intralesional Injection of Talimogene Laherparepvec
John Rieth
NCT07342322 NOT YET RECRUITING
A Prospective, Multicenter, Open-label, Single-arm Phase II Clinical Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With the PraG Strategy for the Treatment of Soft Tissue Sarcoma
First Affiliated Hospital of Guangxi Medical University
NCT06898970 RECRUITING
Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for Angiosarcoma
Varun Monga, MBBS
NCT05046314 RECRUITING
A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma
Shanghai Pharmaceuticals Holding Co., Ltd
NCT05465954 RECRUITING
Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma
Mayo Clinic
NCT04950075 ACTIVE NOT RECRUITING
Study of INBRX-109 in Conventional Chondrosarcoma
Inhibrx Biosciences, Inc
NCT06571734 RECRUITING
XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma
Northwestern University
NCT06849986 RECRUITING
IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)
Fudan University
NCT02568267 ACTIVE NOT RECRUITING
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Hoffmann-La Roche
NCT07321912 NOT YET RECRUITING
Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
Milton S. Hershey Medical Center
NCT05660408 RECRUITING
RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors
University of Florida
NCT06630325 ACTIVE NOT RECRUITING
A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer
OHSU Knight Cancer Institute
NCT03899792 ACTIVE NOT RECRUITING
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors
Eli Lilly and Company
NCT04200443 ACTIVE NOT RECRUITING
Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma
City of Hope Medical Center
NCT04383119 RECRUITING
Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma
Italian Sarcoma Group
NCT06835049 RECRUITING
Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)
Swiss Cancer Institute
NCT03643133 ACTIVE NOT RECRUITING
Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients
UNICANCER
NCT06942442 RECRUITING
A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
Sarcoma Alliance for Research through Collaboration
NCT04796012 RECRUITING
VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors
University of Texas Southwestern Medical Center
NCT03331250 ACTIVE NOT RECRUITING
Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)
Massachusetts General Hospital
NCT04817254 ACTIVE NOT RECRUITING
Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
National Cancer Institute (NCI)
NCT07192068 RECRUITING
Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.
UNICANCER
NCT05039281 RECRUITING
Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma
M.D. Anderson Cancer Center
NCT04416568 ACTIVE NOT RECRUITING
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers
Dana-Farber Cancer Institute
NCT06625190 RECRUITING
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
University of Florida
NCT07089992 RECRUITING
A Study of Pembrolizumab in People With Ultra-Rare Sarcomas
Memorial Sloan Kettering Cancer Center
NCT05926700 RECRUITING
Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard Treatment
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT06416085 RECRUITING
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer
University Health Network, Toronto
NCT05167994 RECRUITING
Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk Sarcoma (SPARE-01)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06943521 RECRUITING
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Tanabe Pharma America, Inc.
NCT02523040 ACTIVE NOT RECRUITING
Lenalidomide for Adult Histiocyte Disorders
Dana-Farber Cancer Institute
NCT05099666 ACTIVE NOT RECRUITING
Lurbinectedin + Doxorubicin In Leiomyosarcoma
Massachusetts General Hospital
NCT06128863 ACTIVE NOT RECRUITING
Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial
Maria Sklodowska-Curie National Research Institute of Oncology
NCT04340843 ACTIVE NOT RECRUITING
Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma
National Cancer Institute (NCI)
NCT05120271 ACTIVE NOT RECRUITING
BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
Sotio Biotech Inc.
NCT05301283 RECRUITING
Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT04284774 ACTIVE NOT RECRUITING
Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
National Cancer Institute (NCI)
NCT04320888 ACTIVE NOT RECRUITING
Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
National Cancer Institute (NCI)
NCT03660826 ACTIVE NOT RECRUITING
Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone
National Cancer Institute (NCI)
NCT03880019 ACTIVE NOT RECRUITING
A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma
National Cancer Institute (NCI)
NCT03213704 ACTIVE NOT RECRUITING
Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03698994 ACTIVE NOT RECRUITING
Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT06333314 RECRUITING
Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
UNICANCER
NCT03834961 ACTIVE NOT RECRUITING
Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia
Children's Oncology Group
NCT04388839 ACTIVE NOT RECRUITING
Evolutionary Therapy for Rhabdomyosarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT04727242 ACTIVE NOT RECRUITING
CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma
Stanford University
NCT07243626 NOT YET RECRUITING
Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT03449108 ACTIVE NOT RECRUITING
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
M.D. Anderson Cancer Center
NCT03589729 RECRUITING
Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers
M.D. Anderson Cancer Center
NCT04624178 ACTIVE NOT RECRUITING
A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma
Memorial Sloan Kettering Cancer Center
NCT07049848 RECRUITING
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
M.D. Anderson Cancer Center
NCT06673628 RECRUITING
Pembrolizumab Plus Lenvatinib in Unresectable Cutaneous Angiosarcoma Patients
National Cancer Center, Japan
NCT04305548 RECRUITING
Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma
Italian Sarcoma Group
NCT04551430 ACTIVE NOT RECRUITING
Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma
Washington University School of Medicine
NCT06521567 ACTIVE NOT RECRUITING
A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
GlaxoSmithKline
NCT06503146 RECRUITING
18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
National Cancer Institute (NCI)
NCT07076186 NOT YET RECRUITING
Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS
M.D. Anderson Cancer Center
NCT05902988 RECRUITING
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Volastra Therapeutics, Inc.
NCT04803877 ACTIVE NOT RECRUITING
SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma
Sarcoma Alliance for Research through Collaboration
NCT02713269 ACTIVE NOT RECRUITING
Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord
M.D. Anderson Cancer Center
NCT03069378 ACTIVE NOT RECRUITING
A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Memorial Sloan Kettering Cancer Center
NCT04278781 ACTIVE NOT RECRUITING
AG-120 in People With IDH1 Mutant Chondrosarcoma
Memorial Sloan Kettering Cancer Center
NCT06176989 RECRUITING
Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors
National Cancer Institute (NCI)
NCT05886634 ACTIVE NOT RECRUITING
A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT05836571 ACTIVE NOT RECRUITING
Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma
National Cancer Institute LAO
NCT06327477 RECRUITING
Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Northwestern University
NCT05515575 ACTIVE NOT RECRUITING
A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA
Memorial Sloan Kettering Cancer Center
NCT04797767 RECRUITING
Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms
University of Washington
NCT04106414 ACTIVE NOT RECRUITING
Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to Treatment
Memorial Sloan Kettering Cancer Center
NCT04438824 ACTIVE NOT RECRUITING
Palbociclib and INCMGA00012 in People With Advanced Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT04668300 ACTIVE NOT RECRUITING
Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma
M.D. Anderson Cancer Center
NCT05019703 RECRUITING
Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study
M.D. Anderson Cancer Center
NCT04370587 RECRUITING
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
ImmVira Pharma Co. Ltd
NCT03141684 ACTIVE NOT RECRUITING
Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma
National Cancer Institute (NCI)
NCT05182164 RECRUITING
Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas
Institut Bergonié
NCT02502786 ACTIVE NOT RECRUITING
Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma
Memorial Sloan Kettering Cancer Center
NCT04577755 ACTIVE NOT RECRUITING
Pomalidomide Treatment in Patients With Kaposi Sarcoma
National Cancer Institute (NCI)
NCT07205185 NOT YET RECRUITING
A Multicenter, Single-arm, Prospective Phase II Clinical Study of Epalrotokewali Combined With Eribulin, Anlotinib, and Radiotherapy for the Treatment of Patients With Advanced Soft Tissue Sarcoma.
Fudan University
NCT05864534 RECRUITING
Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma
Northwestern University
NCT05296564 RECRUITING
Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers
Hadassah Medical Organization
NCT06639074 RECRUITING
Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial
Mayo Clinic
NCT04705818 ACTIVE NOT RECRUITING
Combining Epigenetic And Immune Therapy to Beat Cancer.
Institut Bergoni��
NCT04095208 ACTIVE NOT RECRUITING
Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof-of-concept Randomized Phase II Study
Institut Bergonié
NCT03282344 ACTIVE NOT RECRUITING
A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Memorial Sloan Kettering Cancer Center
NCT04557449 ACTIVE NOT RECRUITING
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Pfizer
NCT07153887 RECRUITING
Vebreltinib for Advanced or Metastatic CCS
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT06528769 RECRUITING
Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma
Gabriel Tinoco
NCT03307616 ACTIVE NOT RECRUITING
Nivolumab With and Without Ipilimumab and Radiation Therapy in Treating Patients With Recurrent or Resectable Undifferentiated Pleomorphic Sarcoma or Dedifferentiated Liposarcoma Before Surgery
M.D. Anderson Cancer Center
NCT05500391 RECRUITING
Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring
Centre Oscar Lambret
NCT04273061 RECRUITING
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
British Columbia Cancer Agency
NCT04079179 RECRUITING
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders
Carl Allen
NCT04751409 RECRUITING
Evaluating the Impact of Limited Compared With Intense Post-Operative Surveillance on Patient-Reported Outcomes in Patients With Stage II-III Soft Tissue Sarcoma of the Trunk and Extremities
M.D. Anderson Cancer Center
NCT06052618 RECRUITING
Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)
National Cancer Institute (NCI)
NCT04515459 RECRUITING
Efficacy of Pre-operative Prehabilitation in Patients With Limb Sarcoma
Institut Claudius Regaud
NCT07014137 RECRUITING
A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas
University Health Network, Toronto
NCT07156643 NOT YET RECRUITING
A Prospective, Single-arm, Multicenter Exploratory Clinical Study of Anlotinib Combined With Bempegaldesleukin and Conventional Chemoradiotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Soft Tissue Sarcoma.
The First Affiliated Hospital with Nanjing Medical University
NCT03819985 ACTIVE NOT RECRUITING
Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk
M.D. Anderson Cancer Center
NCT04977453 RECRUITING
GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors
GI Innovation, Inc.
NCT06389799 RECRUITING
A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)
Lund University Hospital
NCT06445166 RECRUITING
Propranolol for the Treatment of Kaposi Sarcoma in Adults
Washington University School of Medicine
NCT07142863 NOT YET RECRUITING
Envafolimab Combined With Neoadjuvant Chemotherapy Treat Stage IIb Resectable Osteosarcoma Patients
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
NCT07137884 NOT YET RECRUITING
Anlotinib Hydrochloride Capsules in Maintenance Treatment for Intermediate-High Risk Rhabdomyosarcoma in Children
Sun Yat-sen University
NCT04303117 RECRUITING
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
National Cancer Institute (NCI)
NCT06023641 RECRUITING
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
St. Jude Children's Research Hospital
NCT05156268 ACTIVE NOT RECRUITING
A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma
Memorial Sloan Kettering Cancer Center
NCT05864144 ACTIVE NOT RECRUITING
A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Sensei Biotherapeutics, Inc.
NCT02337686 ACTIVE NOT RECRUITING
Pembrolizumab in Treating Patients With Recurrent Glioblastoma
M.D. Anderson Cancer Center
NCT04776525 RECRUITING
Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma
Oslo University Hospital
NCT04874311 RECRUITING
Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma
Institut Bergonié
NCT04968106 RECRUITING
Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)
Institut Bergonié
NCT02790515 ACTIVE NOT RECRUITING
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
St. Jude Children's Research Hospital
NCT06298916 RECRUITING
64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
Lantheus Medical Imaging
NCT05135975 RECRUITING
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors
Nationwide Children's Hospital
NCT04528680 ACTIVE NOT RECRUITING
Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma
Northwestern University
NCT07092306 NOT YET RECRUITING
A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride Liposome Injection Combined With Temozolomide and Vincristine (NALIRI-VT) Versus Irinotecan Combined With Temozolomide and Vincristine (VIT) in Patients With Advanced Ewing's Sarcoma
Tang Xiaodong
NCT03367741 ACTIVE NOT RECRUITING
Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial Cancer
National Cancer Institute (NCI)
NCT06277154 RECRUITING
MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma
HRYZ Biotech Co.
NCT04040205 RECRUITING
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
Medical College of Wisconsin
NCT06367075 RECRUITING
A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT07067255 RECRUITING
Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer
Essen Biotech
NCT05679921 RECRUITING
Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma
Yonsei University
NCT07066982 RECRUITING
Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas
Essen Biotech
NCT07064018 RECRUITING
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
University of California, Irvine
NCT03935893 RECRUITING
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
Udai Kammula
NCT07028086 RECRUITING
VAM in Secondary AML, AML With Extramedullary Involvement, and Myeloid Sarcoma
Ruijin Hospital
NCT07048184 NOT YET RECRUITING
Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing
NHS Greater Glasgow and Clyde
NCT06580002 RECRUITING
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
University of California, Irvine
NCT07032285 RECRUITING
Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas
Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas
NCT06114004 RECRUITING
Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)
Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas
NCT05920798 RECRUITING
Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Mayo Clinic
NCT02650986 ACTIVE NOT RECRUITING
Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1
Roswell Park Cancer Institute
NCT06436612 RECRUITING
Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)
Jonsson Comprehensive Cancer Center
NCT02846987 ACTIVE NOT RECRUITING
Study of Abemaciclib in Dedifferentiated Liposarcoma
Memorial Sloan Kettering Cancer Center
NCT06022159 RECRUITING
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Institut Claudius Regaud
NCT06827717 RECRUITING
Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma
Sun Yat-sen University
NCT03694262 ACTIVE NOT RECRUITING
The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib)
Medical College of Wisconsin
NCT06638931 ACTIVE NOT RECRUITING
Agnostic Therapy in Rare Solid Tumors
Instituto do Cancer do Estado de São Paulo
NCT04140526 ACTIVE NOT RECRUITING
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
OncoC4, Inc.
NCT05941325 RECRUITING
A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma
Shanghai 6th People's Hospital
NCT04072042 RECRUITING
BIOmarker Driven Trial of VEGFR2 Inhibitor in Advanced or Metastatic Sarcoma
Ruijin Hospital
NCT05894018 RECRUITING
Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma
Fujun Zhang
NCT04919629 RECRUITING
APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion
Roswell Park Cancer Institute
NCT06892678 RECRUITING
DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma
Montefiore Medical Center
NCT03414229 ACTIVE NOT RECRUITING
A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Memorial Sloan Kettering Cancer Center
NCT06905132 RECRUITING
Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma
Medical University of South Carolina
NCT05440786 ACTIVE NOT RECRUITING
CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma
Eli Lilly and Company
NCT05457829 RECRUITING
Doxorubicin Hydrochloride Liposome Combined With Irinotecan (AI Regimen) Versus VIT Regimen in the Treatment of First Relapsed and Refractory Pediatric Rhabdomyosarcoma: a Prospective, Open-label, Randomized Controlled, Multicenter, Phase II Clinical Study
Sun Yat-sen University
NCT05588648 RECRUITING
Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma
MedPacto, Inc.
NCT05968768 RECRUITING
To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)
Anna Raciborska
NCT05395741 ACTIVE NOT RECRUITING
Regorafenib in Patients With Refractory Primary Bone Tumors
Institute of Mother and Child, Warsaw, Poland
NCT05601232 ACTIVE NOT RECRUITING
A Phase II Study by Using CICS-1 and SPM-011 Commissioned by CICS and STELLA PHARMA
Stella Pharma Corporation
NCT03197506 ACTIVE NOT RECRUITING
Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma
Mayo Clinic
NCT03114527 ACTIVE NOT RECRUITING
Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)
Fox Chase Cancer Center
NCT06524583 RECRUITING
Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour
UNICANCER
NCT04506008 RECRUITING
Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas
Vanderbilt-Ingram Cancer Center
NCT06721689 RECRUITING
PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors
Theodore Laetsch
NCT05809830 ACTIVE NOT RECRUITING
Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue Sarcomas
Grupo Espanol de Investigacion en Sarcomas
NCT05146440 RECRUITING
Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor
Grupo Espanol de Investigacion en Sarcomas
NCT04802876 ACTIVE NOT RECRUITING
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors
SOLTI Breast Cancer Research Group
NCT03965234 RECRUITING
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Roswell Park Cancer Institute
NCT04785196 RECRUITING
APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors
Ascentage Pharma Group Inc.
NCT03778996 ACTIVE NOT RECRUITING
SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03138161 RECRUITING
SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma
Sarcoma Oncology Research Center, LLC
NCT04165330 ACTIVE NOT RECRUITING
Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors
Sarcoma Oncology Research Center, LLC
NCT04535271 RECRUITING
Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03886311 RECRUITING
Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma
Sarcoma Oncology Research Center, LLC
NCT03548428 RECRUITING
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc)
Centre Antoine Lacassagne
NCT06816771 RECRUITING
Evaluation of the Efficacy and Safety of Pazopanib in Combination with TGI/CIV for Recurrent or Refractory Rhabdomyosarcoma in Children or Adolescents
Shandong Cancer Hospital and Institute
NCT03373097 ACTIVE NOT RECRUITING
Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors
Bambino Gesù Hospital and Research Institute
NCT05619913 RECRUITING
EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine Carcinosarcoma
Australia New Zealand Gynaecological Oncology Group
NCT06476704 NOT YET RECRUITING
Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Institut de cancérologie Strasbourg Europe
NCT04733183 ACTIVE NOT RECRUITING
Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma
Philogen S.p.A.
NCT04902872 ACTIVE NOT RECRUITING
Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors
Cybrexa Therapeutics
NCT03972930 ACTIVE NOT RECRUITING
Hypofractionated Radiotherapy for Soft Tissue Sarcomas
University of Wisconsin, Madison
NCT06778603 RECRUITING
B7-H3 NIR Imaging for Osteosarcoma Surgery
Peking University People's Hospital
NCT03709680 ACTIVE NOT RECRUITING
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
Pfizer
NCT06456359 RECRUITING
Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor
University Hospital Heidelberg
NCT06650514 RECRUITING
A Phase 2 Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma
Vall d'Hebron Institute of Oncology
NCT05688280 ACTIVE NOT RECRUITING
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS
Immunophotonics, Inc.
NCT06126510 RECRUITING
Clinical Study of VG161 in the Treatment of Advanced Bone and Soft Tissue Sarcoma
CNBG-Virogin Biotech (Shanghai) Ltd.
NCT06684327 RECRUITING
Multi-cohort, Single-arm Phase II Study of Albumin-paclitaxel, Ifosfamide, and Cisplatin in the Treatment of Rare Advanced Tumors
Fudan University
NCT06094101 RECRUITING
Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)
University Hospital Tuebingen
NCT06714383 RECRUITING
Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma
Peking University People's Hospital
NCT05824975 RECRUITING
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
GI Innovation, Inc.
NCT06699472 RECRUITING
A Prospective, Randomized, Controlled Clinical Study on the Prevention of Chemotherapy Related Myelosuppression in Patients with Ewing's Sarcoma Using Trilaciclib
Fudan University
NCT02203760 ACTIVE NOT RECRUITING
Pazopanib Vs. Pazopanib Plus Gemcitabine
North Eastern German Society of Gynaecological Oncology
NCT03678883 ACTIVE NOT RECRUITING
9-ING-41 in Patients with Advanced Cancers
Actuate Therapeutics Inc.
NCT04673942 RECRUITING
A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors
EpicentRx, Inc.
NCT06637007 RECRUITING
Phase II Clinical Trial of Chidamide Combined With AK112 for Second-line and Advanced Bone and Soft Tissue Sarcoma
Shanxi Province Cancer Hospital
NCT05301764 RECRUITING
A Study of LVGN6051 Combined with Anlotinib in Patient with Soft Tissue Sarcoma
Lyvgen Biopharma Holdings Limited
NCT04888429 RECRUITING
Camrelizumab Plus Famitinib as Treatment in Patient With Advanced or Metastatic Pulmonary Sarcomatoid Carcinoma
Qian Chu
NCT04166006 RECRUITING
A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT06593899 RECRUITING
The Total Neoadjuvant Therapy for Soft Tissue Sarcoma of the Extremities
Fujian Medical University Union Hospital
NCT05830123 RECRUITING
ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas
Hansoh BioMedical R&D Company
NCT06564272 RECRUITING
A Study of KC1036 in Adolescents With Advanced Ewing Sarcoma
Beijing Konruns Pharmaceutical Co., Ltd.
NCT06551896 NOT YET RECRUITING
Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06524778 NOT YET RECRUITING
Single High-dose Brachytherapy for Giant Osteosarcoma Masses
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
NCT06514313 RECRUITING
Clinical Trial of VIM With VIT in Children With Relapsed and Refractory Soft Tissue Sarcoma.
Yizhuo Zhang
NCT06500091 NOT YET RECRUITING
TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04216953 ACTIVE NOT RECRUITING
MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma
Centre Leon Berard
NCT05876715 RECRUITING
LINNOVATE: Lurbinectedin, Ipilimumab and Nivolumab for Soft Tissue Sarcoma
ERLINDA M GORDON
NCT04535713 RECRUITING
GALLANT: Metronomic Gemcitabine, Doxorubicin, Docetaxel and Nivolumab for Advanced Sarcoma
Sarcoma Oncology Research Center, LLC
NCT05187338 RECRUITING
Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT06456892 RECRUITING
Effectiveness of Pucotenlimab Combined With Standard Chemotherapy Regimen
Sun Yat-sen University
NCT04625907 RECRUITING
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma
University of Birmingham
NCT05955105 RECRUITING
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies
Innolake Biopharm
NCT04480502 ACTIVE NOT RECRUITING
ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma
Tracon Pharmaceuticals Inc.
NCT05396118 ENROLLING BY INVITATION
Simultaneous Hyperpolarized [1-13C]Pyruvate and 18F-FDG PET/MRS in Cancer Patients
Rigshospitalet, Denmark
NCT06384248 NOT YET RECRUITING
Phase II Clinical Study of LTC004 in Patients With Advanced Sarcoma
Letolab
NCT05926492 RECRUITING
A Clinical Study of Surufatinib Combined With Chemotherapy as Neoadjuvant Treatment in Osteosarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04889742 NOT YET RECRUITING
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Charite University, Berlin, Germany
NCT03092323 ACTIVE NOT RECRUITING
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity
Sarcoma Alliance for Research through Collaboration
NCT06114225 RECRUITING
Pulmonary Resectable Osteosarcoma Treated by Metastasectomy and Pre-operative Immunotherapy and Stereotactic Body Radiotherapy (PROMIS): a Prospective Clinical Trial
Ruijin Hospital
NCT06074692 RECRUITING
PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA)
Ruijin Hospital
NCT06041490 NOT YET RECRUITING
Adjuvant Therapy for High-risk Hepatocellular Carcinoma Post Liver Transplantation
Peking Union Medical College Hospital
NCT05839275 RECRUITING
The Combination of Radiotherapy,Surufatinib and Sintilimab in High-Risk Localized Soft Tissue Sarcoma
Fudan University
NCT04758000 RECRUITING
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse
Istituto Ortopedico Rizzoli
NCT05961761 RECRUITING
Propranolol and Pembrolizumab in Advanced Soft Tissue Sarcoma Patients
Niels Junker
NCT05774275 RECRUITING
The Combination of Radiotherapy, Chemotherapy and Immunotherapy in High-Risk Localized Soft Tissue Sarcoma
Fudan University
NCT05193188 RECRUITING
A Study of Anlotinib Combined With or Without PD-1 Antibody on Unresectable High-grade Chondrosarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT05722977 NOT YET RECRUITING
Surufatinib and Envafolimab as Second or More-line Therapy in Advanced Soft Tissue Sarcoma Patients
Peking Union Medical College Hospital
NCT05590572 NOT YET RECRUITING
A Study of Sulfatinib on Relapsed or Refractory Drug Resistant Osteosarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT04616560 SUSPENDED
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
National Cancer Institute (NCI)
NCT03602833 COMPLETED
Phase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma
Royal Marsden NHS Foundation Trust
NCT03006848 COMPLETED
A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma
St. Jude Children's Research Hospital
NCT02942264 TERMINATED
Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
National Cancer Institute (NCI)
NCT04794127 COMPLETED
Study on Trabectedin in Combination With Pioglitazone in Patients Myxoid Liposarcomas With Stable Disease After T Alone.
Mario Negri Institute for Pharmacological Research
NCT05000294 SUSPENDED
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
University of Florida
NCT03123276 COMPLETED
Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma
Royal Marsden NHS Foundation Trust
NCT04890093 SUSPENDED
Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT07301268 SUSPENDED
GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma
Mayo Clinic
NCT03601806 COMPLETED
Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection
AIDS Malignancy Consortium
NCT02945800 COMPLETED
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT05846724 WITHDRAWN
Pembrolizumab Plus Lenvatinib in Previously Treated Classic Kaposi Sarcoma
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
NCT02805725 COMPLETED
Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic Cyclophosphamide
Institut Bergonié
NCT04260802 TERMINATED
A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
Ocellaris Pharma, Inc.
NCT05481645 TERMINATED
Efficacy and Safety of TQB2450 Injection Combined With Chemotherapy ± Anlotinib Hydrochloride Capsules for Advanced Endometrial Cancer or Sarcoma of Uterus.
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06562673 COMPLETED
Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma
Shanghai 6th People's Hospital
NCT04067115 COMPLETED
SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients
Sarcoma Alliance for Research through Collaboration
NCT03077451 COMPLETED
Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma
AIDS Malignancy Consortium
NCT03449901 COMPLETED
ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer
Washington University School of Medicine
NCT02364713 TERMINATED
MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer
Mayo Clinic
NCT05938374 COMPLETED
Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcoma (SPARE-03)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05235100 COMPLETED
Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk Sarcoma (SPARE-02)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT02406781 COMPLETED
Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial
Institut Bergonié
NCT03526679 COMPLETED
Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma
National Taiwan University Hospital
NCT03725605 COMPLETED
LTX-315 and Adoptive T-cell Therapy in Advanced Soft Tissue Sarcoma (ATLAS-IT-04)
Lytix Biopharma AS
NCT03011528 COMPLETED
First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years (CombinaiR3)
Institut Curie
NCT05496569 TERMINATED
TQB3616 Capsules in the Treatment of Dedifferentiated Liposarcoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04725331 TERMINATED
A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors
Transgene
NCT03746080 COMPLETED
Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma
Lawrence D Recht
NCT02875548 COMPLETED
A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study
Epizyme, Inc.
NCT03174197 COMPLETED
Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
M.D. Anderson Cancer Center
NCT03425279 COMPLETED
CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma
BioAtla, Inc.
NCT06084689 WITHDRAWN
Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures
Institut Bergonié
NCT04076579 COMPLETED
Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma
University of Michigan Rogel Cancer Center
NCT03899805 COMPLETED
A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas
Dana-Farber Cancer Institute
NCT05080790 COMPLETED
Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT05026736 TERMINATED
Sintilimab for the Treatment of Locally Advanced, Metastatic, or Recurrent Angiosarcoma, the SiARa Cancer Study
M.D. Anderson Cancer Center
NCT05275426 COMPLETED
A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor
Memorial Sloan Kettering Cancer Center
NCT01931098 COMPLETED
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
National Cancer Institute (NCI)
NCT03137888 COMPLETED
Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma
Emory University
NCT01979393 COMPLETED
IRCI Gynae Sarcomas, High Grade Uterine Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC
NCT03395080 COMPLETED
A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or Carcinosarcoma
Leap Therapeutics, Inc.
NCT03862131 TERMINATED
PROactive Evaluation of Function to Avoid CardioToxicity
Washington University School of Medicine
NCT04220229 TERMINATED
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities
University of Washington
NCT05563272 TERMINATED
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT02611024 COMPLETED
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors
PharmaMar
NCT04530487 TERMINATED
Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults
M.D. Anderson Cancer Center
NCT02601950 COMPLETED
A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma
Epizyme, Inc.
NCT05580588 TERMINATED
Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas
Shanghai Pharma Biotherapeutics USA Inc.
NCT02815995 COMPLETED
Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes
M.D. Anderson Cancer Center
NCT06393751 WITHDRAWN
Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer
National Cancer Institute (NCI)
NCT01125449 WITHDRAWN
Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease
Situs Cancer Research Center
NCT03951571 COMPLETED
Efficacy and Safety of Anlotinib in Adjuvant Therapy for High-grade Soft Tissue Sarcoma
Fudan University
NCT04579757 TERMINATED
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors
Hutchmed
NCT02632448 COMPLETED
A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Esperas Pharma Inc.
NCT03660930 TERMINATED
Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas
University of Washington
NCT02799485 COMPLETED
sEphB4-HSA in Treating Patients With Kaposi Sarcoma
AIDS Malignancy Consortium
NCT03610490 TERMINATED
Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center
NCT02658487 COMPLETED
Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia
Vanderbilt-Ingram Cancer Center
NCT05497843 COMPLETED
Chiauranib for Advanced or Unresectable Soft Tissue Sarcoma(STS)
Chipscreen Biosciences, Ltd.
NCT04383210 TERMINATED
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Elevation Oncology
NCT02584647 TERMINATED
PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors
Gulam Manji
NCT03058289 COMPLETED
A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Intensity Therapeutics, Inc.
NCT02428192 COMPLETED
Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma
National Cancer Institute (NCI)
NCT06494787 WITHDRAWN
A Phase 2 Study Using Aliya PEF Plus Pembro for Sarcoma
Sarcoma Oncology Research Center, LLC
NCT04095221 COMPLETED
A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma
Memorial Sloan Kettering Cancer Center
NCT03190174 COMPLETED
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
Sarcoma Oncology Research Center, LLC
NCT02657005 TERMINATED
TK216 in Patients With Relapsed or Refractory Ewing Sarcoma
Oncternal Therapeutics, Inc
NCT03213678 COMPLETED
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT02249949 COMPLETED
Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery
Alliance for Clinical Trials in Oncology
NCT03220035 COMPLETED
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03213665 COMPLETED
Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03811886 WITHDRAWN
Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma
Case Comprehensive Cancer Center
NCT04791228 WITHDRAWN
A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors
Children's National Research Institute
NCT05302921 COMPLETED
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
Children's National Research Institute
NCT03241745 COMPLETED
A Study of Nivolumab in Selected Uterine Cancer Patients
Memorial Sloan Kettering Cancer Center
NCT03997968 COMPLETED
A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors
Cyteir Therapeutics, Inc.
NCT03809637 COMPLETED
A Study of Pemetrexed Plus Cisplatin in Patients With Refractory Soft Tissue Sarcoma
Yonsei University
NCT03233204 COMPLETED
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT04996004 TERMINATED
A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma
Pfizer
NCT05017103 TERMINATED
Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study
M.D. Anderson Cancer Center
NCT03838744 COMPLETED
Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.
Italian Sarcoma Group
NCT03250325 COMPLETED
Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients with Synovial Sarcoma
Takara Bio Inc.
NCT06217536 WITHDRAWN
Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue Sarcomas
University of California, San Francisco
NCT04183062 WITHDRAWN
BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases
Nicklaus Children's Hospital f/k/a Miami Children's Hospital
NCT03116529 TERMINATED
Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma
University of Maryland, Baltimore
NCT03526250 COMPLETED
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
National Cancer Institute (NCI)
NCT03973918 TERMINATED
Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04887298 COMPLETED
Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) with Pulmonary Metastases
Moleculin Biotech, Inc.
NCT03345485 COMPLETED
Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.
Mundipharma Research Limited
NCT03648489 COMPLETED
Dual mTorc Inhibition in advanCed/Recurrent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (of Clear Cell, Endometrioid and High Grade Serous Type, and Carcinosarcoma)
Imperial College London
NCT05854966 WITHDRAWN
CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Wake Forest University Health Sciences
NCT05879185 TERMINATED
A Study of XmAb23104 in People With Sarcoma
Memorial Sloan Kettering Cancer Center
NCT03277924 COMPLETED
Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas
Grupo Espanol de Investigacion en Sarcomas
NCT05001282 TERMINATED
A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα)
Elucida Oncology
NCT03338959 COMPLETED
Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma
Fred Hutchinson Cancer Center
NCT04154189 COMPLETED
A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma
Eisai Inc.
NCT02978859 COMPLETED
Sitravatinib in Advanced Liposarcoma and Other Soft Tissue Sarcomas
Columbia University
NCT03320330 COMPLETED
Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors
Children's Oncology Group
NCT02636725 COMPLETED
Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas
Jonathan Trent, MD, PhD
NCT02509598 COMPLETED
A Study of Lymphoseek® as a Lymphoid Tissue Targeting Agent in Pediatric Patients With Melanoma, Rhabdomyosarcoma, or Other Solid Tumors Who Are Undergoing Lymph Node Mapping
Cardinal Health 414, LLC
NCT03508726 COMPLETED
High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas
Mohammed Milhem
NCT05093322 COMPLETED
A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumors
Hutchmed
NCT03926936 COMPLETED
FUlvestrant in Gynecological Cancers That Are Potentially Hormone Sensitive: the FUCHSia Study
Frederic Amant
NCT03132155 TERMINATED
QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma
NantPharma, LLC
NCT02624388 TERMINATED
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)
University of Virginia
NCT04742959 COMPLETED
Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT02340884 COMPLETED
A Pilot RCT of the PRISM Intervention for AYAs With Cancer
Seattle Children's Hospital
NCT03711279 TERMINATED
A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma
Jiangsu HengRui Medicine Co., Ltd.
NCT03012620 COMPLETED
Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types
UNICANCER
NCT03015129 COMPLETED
A Study of Durvalumab With or Without Tremelimumab in Endometrial Cancer
Memorial Sloan Kettering Cancer Center
NCT05262101 TERMINATED
Clinical Trial of TQB2858 Injection in the Treatment of Advanced High-grade Sarcoma
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT02470091 COMPLETED
Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma
Children's Oncology Group
NCT05154630 TERMINATED
Study on Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT03422679 TERMINATED
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
Cellestia Biotech AG
NCT04118166 COMPLETED
Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma
Kristen Ganjoo
NCT05116683 TERMINATED
ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma
Benjamin Izar
NCT03458728 TERMINATED
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Bayer
NCT03684811 COMPLETED
A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation
Forma Therapeutics, Inc.
NCT05558280 SUSPENDED
Qarziba for Patients in Relapsed/Refractory High-grade Osteosarcoma
Prof. Franca Fagioli
NCT03056001 COMPLETED
Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma
Wake Forest University Health Sciences
NCT02584309 COMPLETED
Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
Washington University School of Medicine
NCT02484443 COMPLETED
Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma
National Cancer Institute (NCI)
NCT03063632 COMPLETED
Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma
National Cancer Institute (NCI)
NCT02500797 COMPLETED
Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT02304458 COMPLETED
Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas
National Cancer Institute (NCI)
NCT04145700 TERMINATED
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma
Eli Lilly and Company
NCT03860207 TERMINATED
Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers
Y-mAbs Therapeutics
NCT04644315 TERMINATED
A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
Hoffmann-La Roche
NCT02988817 COMPLETED
Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors
Genmab
NCT02661282 COMPLETED
Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma
M.D. Anderson Cancer Center
NCT03317457 COMPLETED
Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma
AIO-Studien-gGmbH
NCT03798106 COMPLETED
A Study of Pazopanib and Durvalumab for Metastatic Soft Tissue Sarcoma
Yonsei University
NCT05582031 WITHDRAWN
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers
Translational Research in Oncology
NCT04190433 WITHDRAWN
Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial
Mayo Clinic
NCT04593758 COMPLETED
To Evaluate Maximally Tolerated Dose (MTD), Safety and Efficacy of CPI-613® (Devimistat) Plus Hydroxychloroquine in Patients With Relapsed or Refractory Clear Cell Sarcoma of Soft Tissue
Cornerstone Pharmaceuticals
NCT04730349 TERMINATED
A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer
Bristol-Myers Squibb
NCT03435640 TERMINATED
REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies
Nektar Therapeutics
NCT04657315 COMPLETED
Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients
CHA University
NCT02511132 COMPLETED
A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma
Gradalis, Inc.
NCT05302570 WITHDRAWN
Neoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPS
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02643303 COMPLETED
A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers
Ludwig Institute for Cancer Research
NCT03590210 COMPLETED
Combined Treatment With Nivolumab and Trabectedin in Patients With Metastatic or Inoperable Soft Tissue Sarcomas
University Medicine Greifswald
NCT03921073 TERMINATED
Study of T-VEC in Locally Advanced Cutaneous Angiosarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT03441360 COMPLETED
Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)
Eisai Inc.
NCT03524898 TERMINATED
NAPAGE: NAb-PAclitaxel and GEmcitabine in Advanced Soft Tissue Sarcoma
Swiss Cancer Institute
NCT02601209 TERMINATED
Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
National Cancer Institute (NCI)
NCT03245450 COMPLETED
Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid Tumors
Eisai Inc.
NCT03810976 COMPLETED
A Study of Eribulin With Gemcitabine in Patients With Advanced Liposarcoma or Leiomyosarcoma
Yonsei University
NCT03275818 COMPLETED
Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma
Grupo Espanol de Investigacion en Sarcomas
NCT02357810 COMPLETED
Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas
Northwestern University
NCT03365791 COMPLETED
PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies
Novartis Pharmaceuticals
NCT02659020 COMPLETED
A Study of Olaratumab (LY3012207) in Participants With Advanced Soft Tissue Sarcoma
Eli Lilly and Company
NCT03074318 TERMINATED
Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery
Fred Hutchinson Cancer Center
NCT03641326 TERMINATED
Sunitinib in Sarcomas of the Central Nervous System
National Cancer Institute (NCI)
NCT03041701 TERMINATED
Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma
National Cancer Institute (NCI)
NCT05042934 WITHDRAWN
Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma
M.D. Anderson Cancer Center
NCT03296553 COMPLETED
Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.
National Institute of Cancerología
NCT02487979 COMPLETED
Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma
National Cancer Institute (NCI)
NCT02452554 COMPLETED
Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma
Children's Oncology Group
NCT04607200 WITHDRAWN
AGEN2034 & AGEN1884 in Patients With Recurrent, Inoperable Angiosarcoma
Agenus Inc.
NCT04648826 WITHDRAWN
Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies
National Cancer Institute (NCI)
NCT02808247 TERMINATED
Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC
NCT02993705 COMPLETED
Trial On Trabectedin In The Treatment Of Advanced Uterine And Ovarian Carcinosarcoma (CS)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
NCT03933761 WITHDRAWN
Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy
Australia New Zealand Gynaecological Oncology Group
NCT02732015 TERMINATED
Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy
M.D. Anderson Cancer Center
NCT04906876 WITHDRAWN
A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas
Brown University
NCT02798406 COMPLETED
Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects
DNAtrix, Inc.
NCT02743078 TERMINATED
Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma
RTOG Foundation, Inc.
NCT02888665 COMPLETED
Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery
Fred Hutchinson Cancer Center
NCT04464967 WITHDRAWN
Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers
NKGen Biotech, Inc.
NCT02581384 TERMINATED
Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors
Dana-Farber Cancer Institute
NCT02448537 COMPLETED
A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas
Massachusetts General Hospital
NCT04149275 WITHDRAWN
Cabozantinib Plus Nivolumab and Ipilimumab in Women With Recurrent Gynecologic Carcinosarcoma
University of Alabama at Birmingham
NCT02423863 COMPLETED
In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®
Oncovir, Inc.
NCT03013127 TERMINATED
A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery
Oslo University Hospital
NCT02301039 COMPLETED
SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas
Sarcoma Alliance for Research through Collaboration
NCT02300545 COMPLETED
Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy
Washington University School of Medicine
NCT03014804 WITHDRAWN
Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen Vaccine and Nivolumab in Treating Patients With Recurrent Glioblastoma
Jonsson Comprehensive Cancer Center
NCT03652298 TERMINATED
Effects of a Neuroscience-based Technique on Cancer Patients Announced of a Palliative Disease Progression and Partners
Centre Oscar Lambret
NCT03698227 TERMINATED
OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT02609984 TERMINATED
Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT03104335 WITHDRAWN
Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial
Peking University People's Hospital
NCT03913806 COMPLETED
FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CW
University Medical Center Groningen
NCT02496741 COMPLETED
Metformin And Chloroquine in IDH1/2-mutated Solid Tumors
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT03121833 COMPLETED
Endostar Combined With Chemotherapy for Stage Ⅳ Soft Tissue Sarcoma
Tianjin Medical University Cancer Institute and Hospital
NCT02849366 COMPLETED
Combination of Cryosurgery and NK Immunotherapy for Recurrent Sarcoma
Fuda Cancer Hospital, Guangzhou
NCT03397186 WITHDRAWN
Immune Changes Following Trabectedin in Patients With Metastatic or Unresectable Sarcoma
Fred Hutchinson Cancer Center
NCT02689336 WITHDRAWN
Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors
Washington University School of Medicine
NCT02575066 TERMINATED
Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients
The Netherlands Cancer Institute
NCT02718482 TERMINATED
Phase II Trial for the Treatment of Relapsed Osteosarcoma
Italian Sarcoma Group
NCT02303262 COMPLETED
SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma
Sarcoma Alliance for Research through Collaboration
NCT02267083 COMPLETED
Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma
Gem Pharmaceuticals
NCT03149120 WITHDRAWN
Study of Nivolumab With or Without Pazopanib in Metastatic or Unresectable Soft Tissue Sarcomas
NYU Langone Health
NCT02367651 WITHDRAWN
Study of Pazopanib Versus Placebo as Maintenance Therapy for Advanced Soft Tissue Sarcoma
GlaxoSmithKline
NCT02521090 WITHDRAWN
EGFRBi-Armed Autologous T Cells in Treating Patients With Recurrent or Refractory Glioblastoma
Barbara Ann Karmanos Cancer Institute
NCT02137564 WITHDRAWN
Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi Sarcoma
AIDS Malignancy Consortium
NCT05711615 RECRUITING
Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma
National Cancer Institute (NCI)
NCT07422363 NOT YET RECRUITING
Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma
National Cancer Institute (NCI)
NCT04092270 ACTIVE NOT RECRUITING
A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer
National Cancer Institute (NCI)
NCT02298959 ACTIVE NOT RECRUITING
Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer
National Cancer Institute (NCI)
NCT05691504 RECRUITING
Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
National Cancer Institute (NCI)
NCT04704661 RECRUITING
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
National Cancer Institute (NCI)
NCT04514484 ACTIVE NOT RECRUITING
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
National Cancer Institute (NCI)
NCT07297160 NOT YET RECRUITING
CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors
Baylor College of Medicine
NCT06066138 RECRUITING
A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
National Cancer Institute (NCI)
NCT07444619 NOT YET RECRUITING
A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas
M.D. Anderson Cancer Center
NCT07144254 RECRUITING
Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma
Emory University
NCT06492954 RECRUITING
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
Emory University
NCT07297979 RECRUITING
Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)
Amgen
NCT06474676 RECRUITING
T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.
M.D. Anderson Cancer Center
NCT06308419 RECRUITING
A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions
M.D. Anderson Cancer Center
NCT04420975 ACTIVE NOT RECRUITING
Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma
Jonsson Comprehensive Cancer Center
NCT02659930 ACTIVE NOT RECRUITING
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
National Cancer Institute (NCI)
NCT06934889 RECRUITING
Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma
Memorial Sloan Kettering Cancer Center
NCT07197554 RECRUITING
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
SEED Therapeutics, Inc.
NCT07148050 RECRUITING
Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells
Seattle Children's Hospital
NCT07297667 NOT YET RECRUITING
GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours
Canadian Cancer Trials Group
NCT07374848 RECRUITING
Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors
Zai Lab (Shanghai) Co., Ltd.
NCT06440005 RECRUITING
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
Angiex, Inc.
NCT07227571 RECRUITING
Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial
Fred Hutchinson Cancer Center
NCT07222735 RECRUITING
Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas
St. Jude Children's Research Hospital
NCT07211737 NOT YET RECRUITING
NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma
Baylor College of Medicine
NCT03715933 RECRUITING
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Inhibrx Biosciences, Inc
NCT05813327 ACTIVE NOT RECRUITING
Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma
Washington University School of Medicine
NCT03628209 ACTIVE NOT RECRUITING
Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT04969835 RECRUITING
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
Avacta Life Sciences Ltd
NCT03120624 ACTIVE NOT RECRUITING
VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer
Mayo Clinic
NCT05352750 ACTIVE NOT RECRUITING
Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors
Sonnet BioTherapeutics
NCT03900793 RECRUITING
Losartan + Sunitinib in Treatment of Osteosarcoma
University of Colorado, Denver
NCT05542407 RECRUITING
ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
UNC Lineberger Comprehensive Cancer Center
NCT07194044 RECRUITING
Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes
H. Lee Moffitt Cancer Center and Research Institute
NCT02432963 ACTIVE NOT RECRUITING
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy
City of Hope Medical Center
NCT07172958 RECRUITING
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
Children's National Research Institute
NCT05827614 ACTIVE NOT RECRUITING
Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications
Boundless Bio, Inc.
NCT04216329 ACTIVE NOT RECRUITING
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma
National Cancer Institute (NCI)
NCT04995003 RECRUITING
HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma
Baylor College of Medicine
NCT04377932 ACTIVE NOT RECRUITING
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Baylor College of Medicine
NCT05264974 RECRUITING
Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization
University of Florida
NCT07261631 RECRUITING
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
Novartis Pharmaceuticals
NCT06865664 RECRUITING
FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma
National Cancer Institute (NCI)
NCT06968988 RECRUITING
Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma
Washington University School of Medicine
NCT04616248 ACTIVE NOT RECRUITING
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors
University of Southern California
NCT05830084 ACTIVE NOT RECRUITING
Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing Sarcoma
Gustave Roussy, Cancer Campus, Grand Paris
NCT07029399 RECRUITING
A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
NiKang Therapeutics, Inc.
NCT02390752 RECRUITING
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
National Cancer Institute (NCI)
NCT05400603 RECRUITING
Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma
Emory University
NCT05075993 ACTIVE NOT RECRUITING
Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors
M.D. Anderson Cancer Center
NCT04902443 RECRUITING
Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV
National Cancer Institute (NCI)
NCT06021626 RECRUITING
A Study of CRD3874-SI in People With Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT04541082 RECRUITING
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Jazz Pharmaceuticals
NCT06441331 RECRUITING
Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
ITM Solucin GmbH
NCT02869217 ACTIVE NOT RECRUITING
Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
University Health Network, Toronto
NCT05859074 RECRUITING
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Memorial Sloan Kettering Cancer Center
NCT07027423 NOT YET RECRUITING
BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas
University Health Network, Toronto
NCT02811523 RECRUITING
In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma
University Health Network, Toronto
NCT05238883 ACTIVE NOT RECRUITING
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
HiFiBiO Therapeutics
NCT05312411 ACTIVE NOT RECRUITING
A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma
Seattle Children's Hospital
NCT04483778 ACTIVE NOT RECRUITING
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
NCT03618381 ACTIVE NOT RECRUITING
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
NCT02192359 ACTIVE NOT RECRUITING
Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
City of Hope Medical Center
NCT06156410 RECRUITING
Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas
Children's Hospital of Philadelphia
NCT06025747 RECRUITING
Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma
University of Washington
NCT03173976 ACTIVE NOT RECRUITING
Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial
Mohammed Milhem
NCT07224568 NOT YET RECRUITING
Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors
Seattle Children's Hospital
NCT06198296 RECRUITING
Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
Baylor College of Medicine
NCT06414434 RECRUITING
BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma
Michael Wagner, MD
NCT04555577 RECRUITING
Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma
M.D. Anderson Cancer Center
NCT06483048 RECRUITING
MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer
Mayo Clinic
NCT04897321 RECRUITING
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
St. Jude Children's Research Hospital
NCT06957431 RECRUITING
Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma
Washington University School of Medicine
NCT04185883 ACTIVE NOT RECRUITING
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
Amgen
NCT05621668 RECRUITING
A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma
M.D. Anderson Cancer Center
NCT02508038 RECRUITING
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
University of Wisconsin, Madison
NCT06083883 RECRUITING
Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1
M.D. Anderson Cancer Center
NCT05039801 RECRUITING
IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
M.D. Anderson Cancer Center
NCT06812052 RECRUITING
Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior to Surgery
Brigham and Women's Hospital
NCT05735184 RECRUITING
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Kura Oncology, Inc.
NCT04337177 RECRUITING
Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors
Valent Technologies, LLC
NCT05227326 RECRUITING
AOH1996 for the Treatment of Refractory Solid Tumors
City of Hope Medical Center
NCT06926283 RECRUITING
A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors
Hangzhou DAC Biotechnology Co., Ltd.
NCT03361436 ACTIVE NOT RECRUITING
Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery
OHSU Knight Cancer Institute
NCT03896568 RECRUITING
MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma
M.D. Anderson Cancer Center
NCT03721068 RECRUITING
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
UNC Lineberger Comprehensive Cancer Center
NCT05492682 ACTIVE NOT RECRUITING
START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer
Valo Therapeutics Oy
NCT06789172 RECRUITING
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
Epkin
NCT06942143 RECRUITING
An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors
Guangzhou FineImmune Biotechnology Co., LTD.
NCT06508307 RECRUITING
A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors
GONGCHU Biotechnology Co., Ltd
NCT07134842 RECRUITING
A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment.
University College, London
NCT07118176 RECRUITING
Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers
Jonsson Comprehensive Cancer Center
NCT06614855 ACTIVE NOT RECRUITING
A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma
James Markert, MD
NCT03657576 ACTIVE NOT RECRUITING
Trial of C134 in Patients With Recurrent GBM
University of Alabama at Birmingham
NCT05821231 ACTIVE NOT RECRUITING
Study Evaluating the Safety and Efficacy of MEDI5752 in Combination With Stereotactic Radiotherapy in Patients With Metastatic Sarcoma
Institut Claudius Regaud
NCT03635632 ACTIVE NOT RECRUITING
C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)
Baylor College of Medicine
NCT06644755 RECRUITING
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Daiichi Sankyo
NCT05857969 RECRUITING
Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Florida International University
NCT05103631 RECRUITING
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors
Baylor College of Medicine
NCT07052383 NOT YET RECRUITING
Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas
Tcelltech Inc.
NCT04477200 ACTIVE NOT RECRUITING
Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma
University of Michigan Rogel Cancer Center
NCT06566092 RECRUITING
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
Iovance Biotherapeutics, Inc.
NCT04521686 ACTIVE NOT RECRUITING
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations
Eli Lilly and Company
NCT06896110 ENROLLING BY INVITATION
Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma
Andrew P. Groves
NCT04299113 ACTIVE NOT RECRUITING
Mocetinostat With Vinorelbine in Children, Adolescents & Young Adults With Refractory and/or Recurrent Rhabdomyosarcoma
Jonsson Comprehensive Cancer Center
NCT05999396 RECRUITING
FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal Cancer
German Cancer Research Center
NCT05698524 RECRUITING
A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma
University of Nebraska
NCT04715191 RECRUITING
Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Baylor College of Medicine
NCT06500819 RECRUITING
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
Crystal Mackall, MD
NCT06889766 RECRUITING
NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma
Centre Hospitalier Universitaire Vaudois
NCT03478462 ACTIVE NOT RECRUITING
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
Cellectar Biosciences, Inc.
NCT05210374 RECRUITING
Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas
Case Comprehensive Cancer Center
NCT06839703 NOT YET RECRUITING
International Phase I Trial of Dinutuximab Beta With VDC/IE in GD2-Positive Ewing Sarkoma
Prof. Dr. Dirk Reinhardt
NCT03860272 ACTIVE NOT RECRUITING
Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer
Agenus Inc.
NCT06748872 NOT YET RECRUITING
EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma
Medigene AG
NCT06537596 RECRUITING
89Zr-olaratumab Dosimetry in Participants With Soft Tissue Sarcoma
Telix Pharmaceuticals (Innovations) Pty Ltd
NCT03054792 ENROLLING BY INVITATION
Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas
The Hospital for Sick Children
NCT06699576 NOT YET RECRUITING
ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma.
Hansoh BioMedical R&D Company
NCT04511871 ACTIVE NOT RECRUITING
A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
Shanghai PerHum Therapeutics Co., Ltd.
NCT05130255 RECRUITING
GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2
Y-mAbs Therapeutics
NCT06610071 NOT YET RECRUITING
NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG Technique
The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
NCT06235125 RECRUITING
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
Ann & Robert H Lurie Children's Hospital of Chicago
NCT05646082 RECRUITING
Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination Antiretroviral Therapy (cART) Refractory HIV Associated Kaposi Sarcoma
Imperial College London
NCT06412458 NOT YET RECRUITING
IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma
Beijing Immunochina Medical Science & Technology Co., Ltd.
NCT06087341 RECRUITING
A Phase I Trial of Memory T Cells Expressing an NKG2D Chimeric Antigen Receptor in Children, Adolescents and Young Adults With Advanced Sarcoma
Antonio Pérez Martínez
NCT04032964 ACTIVE NOT RECRUITING
Dose Finding Study of L19TNF and Doxorubicin in Patients With STS
Philogen S.p.A.
NCT06340204 RECRUITING
Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma
Peking University People's Hospital
NCT04282044 RECRUITING
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
BioEclipse Therapeutics
NCT04595994 RECRUITING
Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma and Osteosarcoma
Grupo Espanol de Investigacion en Sarcomas
NCT05363826 RECRUITING
Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®
Photolitec LLC
NCT05361954 NOT YET RECRUITING
Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors
Sorrento Therapeutics, Inc.
NCT02787642 COMPLETED
A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma
Institut Bergonié
NCT04052334 COMPLETED
Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma
H. Lee Moffitt Cancer Center and Research Institute
NCT04619056 COMPLETED
First-in-man Clinical Trial of CEB-01 PLGA Membrane in Recurrent or Locally Advanced Retroperitoneal Soft Tissue Sarcoma
CEBIOTEX
NCT05799612 WITHDRAWN
Phase I Study of TH1 Dendritic Cell Immunotherapy for the Treatment of Cutaneous Angiosarcoma
M.D. Anderson Cancer Center
NCT04037527 TERMINATED
Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities
Wake Forest University Health Sciences
NCT05116254 TERMINATED
Sarcomas and DDR-Inhibition; a Combined Modality Study
The Netherlands Cancer Institute
NCT06193174 TERMINATED
Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)
University of Alabama at Birmingham
NCT04751383 COMPLETED
Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
National Cancer Institute (NCI)
NCT02408861 TERMINATED
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT04204941 TERMINATED
Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma
Epizyme, Inc.
NCT02709226 COMPLETED
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
National Cancer Institute (NCI)
NCT06438783 TERMINATED
TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT05252416 TERMINATED
(VELA) Study of BLU-222 in Advanced Solid Tumors
Blueprint Medicines Corporation
NCT06806228 SUSPENDED
Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)
Petrov, Andrey
NCT02936102 TERMINATED
A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
Novartis Pharmaceuticals
NCT03107780 TERMINATED
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
National Cancer Institute (NCI)
NCT04539366 SUSPENDED
Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial
National Cancer Institute (NCI)
NCT05229601 TERMINATED
A Study of HFB301001 in Adult Patients With Advanced Solid Tumors
HiFiBiO Therapeutics
NCT03514407 TERMINATED
A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma
Incyte Corporation
NCT03217266 COMPLETED
Navtemadlin and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma
National Cancer Institute (NCI)
NCT03085225 COMPLETED
Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.
Institut Bergonié
NCT04242238 COMPLETED
Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas
Memorial Sloan Kettering Cancer Center
NCT06670976 WITHDRAWN
Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma
Roswell Park Cancer Institute
NCT05605522 TERMINATED
A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours
3B Pharmaceuticals GmbH
NCT02784795 TERMINATED
A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors
Eli Lilly and Company
NCT05858710 COMPLETED
Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma
Thermosome GmbH
NCT06299163 TERMINATED
NM32-2668 in Adult Patients With Selected Advanced Solid Tumors
Numab Therapeutics AG
NCT05432193 TERMINATED
FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)
POINT Biopharma, a wholly owned subsidiary of Eli Lilly and Company
NCT02517918 COMPLETED
Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Institut Bergonié
NCT03452930 COMPLETED
Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma
M.D. Anderson Cancer Center
NCT04811196 COMPLETED
A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients
University Health Network, Toronto
NCT02186509 COMPLETED
Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT04553692 TERMINATED
Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers
IGM Biosciences, Inc.
NCT05166577 TERMINATED
Nanatinostat Plus Valganciclovir in Advanced EBV+ Solid Tumors and in Combination With Pembrolizumab in EBV+ RM-NPC
Viracta Therapeutics, Inc.
NCT03157167 COMPLETED
An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)
Navidea Biopharmaceuticals
NCT04965753 TERMINATED
FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors
Foghorn Therapeutics Inc.
NCT04537715 COMPLETED
Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels
Epizyme, Inc.
NCT03552471 COMPLETED
Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Ohio State University Comprehensive Cancer Center
NCT04397679 TERMINATED
Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma
Barbara Ann Karmanos Cancer Institute
NCT05100628 TERMINATED
A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma
Noxopharm Limited
NCT05355753 TERMINATED
A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors
C4 Therapeutics, Inc.
NCT02101905 COMPLETED
Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
National Cancer Institute (NCI)
NCT03960060 TERMINATED
A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors
Shanghai PerHum Therapeutics Co., Ltd.
NCT04521946 WITHDRAWN
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
M.D. Anderson Cancer Center
NCT03126591 COMPLETED
A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company
NCT03990597 WITHDRAWN
StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord
M.D. Anderson Cancer Center
NCT02601937 COMPLETED
EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma
Epizyme, Inc.
NCT02484391 COMPLETED
CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma
Wake Forest University Health Sciences
NCT03604783 TERMINATED
Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT06252727 WITHDRAWN
Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)
University of California, Davis
NCT02595866 COMPLETED
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
National Cancer Institute (NCI)
NCT03206177 COMPLETED
Paclitaxel/Carboplatin + Galunisertib for Patients With Carcinosarcoma of the Uterus or Ovary
University of Oklahoma
NCT03752398 COMPLETED
A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)
Xencor, Inc.
NCT05538572 COMPLETED
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors
Prelude Therapeutics
NCT05578820 COMPLETED
Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
Gene Surgery LLC
NCT04893018 TERMINATED
NT-I7 for Kaposi Sarcoma in Patients With or Without HIV
Fred Hutchinson Cancer Center
NCT05420727 COMPLETED
Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approach
John O. Prior
NCT03670069 TERMINATED
Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas
Fred Hutchinson Cancer Center
NCT05061537 TERMINATED
Study of PF-07263689 in Participants With Selected Advanced Solid Tumors
Pfizer
NCT03043391 COMPLETED
Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children
Istari Oncology, Inc.
NCT03727789 TERMINATED
CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma
Roswell Park Cancer Institute
NCT03761095 COMPLETED
A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)
PTC Therapeutics
NCT04900766 TERMINATED
A Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Advanced Bone and Soft Tissue Sarcoma
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT04341311 TERMINATED
Phase I Study of Marizomib + Panobinostat for Children With DIPG
Dana-Farber Cancer Institute
NCT04176016 TERMINATED
Phase I Study of Radiolabeled OTSA101-DTPA in Patients With Relapsed or Refractory Synovial Sarcoma
OncoTherapy Science, Inc.
NCT03454451 COMPLETED
CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers
Corvus Pharmaceuticals, Inc.
NCT05159518 COMPLETED
A Study of PRT2527 in Participants With Advanced Solid Tumors
Prelude Therapeutics
NCT02498665 COMPLETED
A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies
Sumitomo Pharma America, Inc.
NCT02736565 COMPLETED
Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma
Gradalis, Inc.
NCT05905341 WITHDRAWN
Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.
Pfizer
NCT03240861 TERMINATED
Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer
Jonsson Comprehensive Cancer Center
NCT02644460 COMPLETED
Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Emory University
NCT03450122 COMPLETED
Modified T Cells, Chemotherapy, and Aldesleukin With or Without LV305 and CMB305 in Treating Participants With Advanced or Recurrent Sarcoma
M.D. Anderson Cancer Center
NCT02897375 COMPLETED
Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors
Emory University
NCT02658981 COMPLETED
Anti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02386826 COMPLETED
INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme
SCRI Development Innovations, LLC
NCT02536183 TERMINATED
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors
AeRang Kim
NCT03009201 COMPLETED
Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery
OHSU Knight Cancer Institute
NCT03829436 COMPLETED
TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers
Tempest Therapeutics
NCT03399448 TERMINATED
NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
University of Pennsylvania
NCT04091503 COMPLETED
Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma
Center Trials & Treatment Europe
NCT04802070 COMPLETED
Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment.
Prof. Franca Fagioli
NCT02890368 TERMINATED
Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides
Pfizer
NCT04837677 COMPLETED
A Study of PRT1419 in Patients With Advanced Solid Tumors
Prelude Therapeutics
NCT02890758 COMPLETED
Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803
Brenda Cooper, MD
NCT02664363 TERMINATED
EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma
Daniel Landi
NCT04430842 COMPLETED
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
Quadriga Biosciences, Inc.
NCT02311920 COMPLETED
Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
National Cancer Institute (NCI)
NCT03612466 WITHDRAWN
A Dose Finding Study of CycloSam® Combined With External Beam Radiotherapy
Albert Einstein College of Medicine
NCT04861948 TERMINATED
IBI188 Combination Therapy in Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT03209869 WITHDRAWN
Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2
University of Wisconsin, Madison
NCT03924245 TERMINATED
Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers
Vanderbilt-Ingram Cancer Center
NCT02982941 COMPLETED
Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors
MacroGenics
NCT02573259 COMPLETED
A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors
Pfizer
NCT03042819 COMPLETED
Study of Selinexor and Doxorubicin in Advanced Soft Tissue Sarcomas
University Health Network, Toronto
NCT03056599 COMPLETED
Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma
Presage Biosciences
NCT03020602 COMPLETED
BPM31510 in Treating Patients With Recurrent High-Grade Glioma Previously Treated With Bevacizumab
Seema Nagpal
NCT04854044 WITHDRAWN
ONC201 and Radiation Therapy Before Surgery for the Treatment of Recurrent Glioblastoma
Jonsson Comprehensive Cancer Center
NCT03730077 TERMINATED
FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas
University of Pennsylvania
NCT02748135 COMPLETED
A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma
Oncurious NV
NCT03139331 COMPLETED
PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma
University of California, San Francisco
NCT03782363 WITHDRAWN
Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment.
Italian Sarcoma Group
NCT02343172 COMPLETED
Study of Safety and Efficacy of HDM201 in Combination With LEE011 in Patients With Liposarcoma
Novartis Pharmaceuticals
NCT03880123 WITHDRAWN
Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma
Matthew Ingham
NCT03283696 COMPLETED
A Study of Olaratumab (LY3012207), Doxorubicin, and Ifosfamide in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Eli Lilly and Company
NCT02387125 TERMINATED
Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1
Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT02502708 COMPLETED
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
NewLink Genetics Corporation
NCT02390843 COMPLETED
Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
Emory University
NCT02576665 TERMINATED
A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
Tocagen Inc.
NCT02326025 COMPLETED
A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma
Eli Lilly and Company
NCT02795819 TERMINATED
Study of the Pan-DAC Inhibitor AR-42 and Pazopanib in Advanced Sarcoma and Kidney Cancer
Virginia Commonwealth University
NCT02783599 COMPLETED
A Study of Olaratumab (LY3012207) in Participants With Soft Tissue Sarcoma
Eli Lilly and Company
NCT02337426 COMPLETED
Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Virginia Commonwealth University
NCT02565758 COMPLETED
ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors
AbbVie
NCT02557854 WITHDRAWN
HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors
Theodore Laetsch
NCT03437070 WITHDRAWN
Trabectedin, Doxorubicin and Olaratumab in Patients With Metastatic or Recurrent Leiomyosarcoma
University of Miami
NCT03111069 WITHDRAWN
Study of Doxorubicin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and Intraoperative Brachytherapy for Unresectable or Refractory Pelvic and Abdominal Rhabdomyosarcoma and Undifferentiated Sarcomas in Children
M.D. Anderson Cancer Center
NCT03275558 WITHDRAWN
Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of Glioblastoma
Center Trials & Treatment
NCT02839694 WITHDRAWN
Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
National Cancer Institute (NCI)
NCT03007771 WITHDRAWN
Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia
Washington University School of Medicine
NCT02210104 WITHDRAWN
Adoptive Therapy Using Antigen-Specific CD4 T-Cells
M.D. Anderson Cancer Center
NCT02319824 COMPLETED
NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy
Fred Hutchinson Cancer Center
NCT02464332 WITHDRAWN
Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery
Blaze Bioscience Inc.
NCT03244020 ENROLLING BY INVITATION
LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology
Massachusetts General Hospital
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Guerbet
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Tranexamic Acid in Radical Resection and Endoprosthetic Reconstruction
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Quality of Life in Patients With Non-adipocyte Soft Tissue Sarcoma Under Palliative Chemotherapy or Pazopanib
GWT-TUD GmbH
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Institut Claudius Regaud
Data: ClinicalTrials.gov