TheraRadar

Pharma Intelligence, Simplified

Landscape → Infectious Disease

Sepsis

327 clinical trials

111 active
/
327 total (since 2015)
12
Phase 1 Active
47 total
44
Phase 2 Active
130 total
30
Phase 3 Active
102 total
40
Phase 4 Active
92 total

Top Sponsors (Industry)

Sorted by active Active Done Failed
Bayer 1 0 1
Tianjin Chasesun Pharmaceutical Co., LTD 1 1 0
Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. 1 0 0
Regeneron 1 0 0
AstraZeneca 1 0 0
Op-T LLC 1 0 0
Artcline GmbH 1 0 0
Vivacelle Bio 1 0 0
Grand Medical Pty Ltd. 1 0 0
Dascena 0 0 3
Bristol-Myers Squibb 0 2 1
NCT06900140 RECRUITING
Adjunctive Methylene Blue in Septic Shock
Dr. Shannon M. Fernando n=50
NCT05179499 RECRUITING
Early Vasopressors in Sepsis
NHS Greater Glasgow and Clyde n=1,006
NCT07380347 NOT YET RECRUITING
Effect of N-acetylcysteine as Adjunct Therapy on the Clinical Outcome of Neonatal Sepsis
Ain Shams University n=50
NCT06592586 RECRUITING
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women
Minervax ApS n=338
NCT06464510 RECRUITING
Norepinephrine and Vasopressin for Rescue Versus Early Vasopressin for Vasopressor Dependent Sepsis
Hospital do Coracao n=2,800
NCT05909683 ACTIVE NOT RECRUITING
Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial)
Hellenic Institute for the Study of Sepsis n=190
NCT07342205 RECRUITING
A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation
Shanghai University of Traditional Chinese Medicine n=60
NCT07332325 NOT YET RECRUITING
STeroids and Enhanced Spectrum Antibiotics for the Treatment of Patients in Africa With Refractory Sepsis
University of Virginia n=344
NCT07264543 RECRUITING
Early Methylene Blue in the Microhemodynamics of Septic Shock Patients
Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva n=50
NCT07067866 RECRUITING
Weaning Approaches for Vasopressin in Sepsis
Hospital Nossa Senhora da Conceicao n=82
NCT07212582 NOT YET RECRUITING
Human Albumin for Resuscitation in Surgical Septic Shock: A Randomized Controlled Trial (ALBUS Study)
Mahidol University n=304
NCT03401398 RECRUITING
Stress Hydrocortisone In Pediatric Septic Shock
Jerry Zimmerman n=500
NCT07063095 RECRUITING
A Combination Therapy With Ceftazidime and Fosfomycin Will be Compared to Ceftazidime Alone in Hospitalized Adult Patients With Suspected Severe Gram-negative Bacterial Infections
Angela HUTTNER n=100
NCT05267821 RECRUITING
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
Nationwide Children's Hospital n=500
NCT04589546 ACTIVE NOT RECRUITING
Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock?
Centre Hospitalier Universitaire, Amiens n=310
NCT04748796 RECRUITING
Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility
Centre Hospitalier Universitaire, Amiens n=360
NCT07052084 NOT YET RECRUITING
Systematic Adjunction of Vasopressine in Septic Shock
Assistance Publique Hopitaux De Marseille n=120
NCT04910464 RECRUITING
Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
Assiut University n=80
NCT04931225 RECRUITING
LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS)
Assistance Publique - Hôpitaux de Paris n=44
NCT06893939 RECRUITING
Limited Versus Extended Trophic Feeding (LET-FEED) Trial
University of Washington n=350
NCT06072430 RECRUITING
A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)
Vivacelle Bio n=46
NCT06851078 NOT YET RECRUITING
Evaluation of Early Administration of Levetiracetam in the Prevention and Treatment Encephalopathy in Septic Shock: Randomized, Double-blind, Placebo-controlled Trial
Assistance Publique - Hôpitaux de Paris n=280
NCT06696391 NOT YET RECRUITING
Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock
Western University, Canada n=80
NCT03797157 ACTIVE NOT RECRUITING
Human Milk Fortification in Extremely Preterm Infants
Thomas Abrahamsson, MD, PhD n=229
NCT04031573 RECRUITING
Ivabradine for Heart Rate Control In Septic Shock
Assistance Publique - Hôpitaux de Paris n=429
NCT06377397 NOT YET RECRUITING
Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates
Indian Council of Medical Research n=1,500
NCT06181422 RECRUITING
Metformin and Lactoferrin in Sepsis in Icu
Tanta University n=60
NCT02707497 RECRUITING
The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia
Ruilan Wang n=200
NCT06306001 NOT YET RECRUITING
Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shock
Post Graduate Institute of Medical Education and Research, Chandigarh n=130
NCT05565222 RECRUITING
Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit
Assistance Publique - Hôpitaux de Paris n=600
NCT03677102 COMPLETED
Fluids in Septic Shock (FISSH)
McMaster University n=1,113
NCT05208242 COMPLETED
Strong Albumin Solutions in Patients With Septic Shock
Manchester University NHS Foundation Trust n=47
NCT06532240 COMPLETED
Methylene Blue for the Treatment of Septic Shock
Northern Jiangsu People's Hospital n=88
NCT03953677 TERMINATED
Evaluation of the Effect of Dexmedetomidine on Phenylephrine Response During Refractory Septic Shock
Centre Hospitalier Universitaire Dijon n=32
NCT03528213 COMPLETED
Utility of Sodium Lactate Infusion During Septic Shock
University Hospital, Lille n=59
NCT04166331 COMPLETED
Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion
University Hospital, Limoges n=136
NCT02473263 COMPLETED
Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock
Assistance Publique - Hôpitaux de Paris n=398
NCT03706053 TERMINATED
Midodrine Use in Septic Shock
University of Virginia n=10
NCT02361528 COMPLETED
GM-CSF to Decrease ICU Acquired Infections
Hospices Civils de Lyon n=166
NCT02664753 TERMINATED
L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury
Centre Hospitalier Universitaire de Nīmes n=254
NCT05856227 COMPLETED
Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age
Basilea Pharmaceutica n=9
NCT06122909 COMPLETED
The Effect Of Resuscitation Guided By Two Different Dynamic Parameters On Time To Normalization Of The Capillary Refill Time In Adult Patients With Septic Shock
Kasr El Aini Hospital n=90
NCT04172012 COMPLETED
Use of Probiotics to Reduce Infections, Death and ESBL Colonisation
Haydom Lutheran Hospital n=2,000
NCT03654001 COMPLETED
ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED)
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico n=1,319
NCT02820987 COMPLETED
PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock
Centre Hospitalier Universitaire de Besancon n=119
NCT05266001 TERMINATED
GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS
Nationwide Children's Hospital n=141
NCT05955612 COMPLETED
Use of Procalcitonin, a Blood Test to Guide Antibiotic Therapy for Sepsis in Adults
University of Oxford n=532
NCT04475081 COMPLETED
Use of a Live Attenuated Vaccine as an Immune-based Preventive Against COVID-19-associated Sepsis
Louisiana State University Health Sciences Center in New Orleans n=50
NCT03869385 TERMINATED
Albumin Replacement Therapy in Septic Shock
Jena University Hospital n=440
NCT03871491 COMPLETED
Azithromycin-Prevention in Labor Use Study (A-PLUS)
NICHD Global Network for Women's and Children's Health n=58,747
NCT04540094 COMPLETED
Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital
University of Edinburgh n=300
NCT04152980 COMPLETED
Pentoxifylline Dose Optimization in Neonatal Sepsis
Erasmus Medical Center n=30
NCT06005558 COMPLETED
Low Dose Versus High Dose Methylene Blue in Septic Patients
National Cancer Institute, Egypt n=90
NCT03788837 COMPLETED
ILOPROST in Septic Shock With Persistent Microperfusion Defects (I-MICRO)
Assistance Publique - Hôpitaux de Paris n=240
NCT03837171 COMPLETED
TRANSfusion in Patients With Onco-hematological Malignancies ResusciTated From Septic Shock
Assistance Publique - Hôpitaux de Paris n=192
NCT06461390 COMPLETED
The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock
Indonesia University n=42
NCT04123444 COMPLETED
Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ Failure
Jakob Stensballe, MD, PhD n=279
NCT05192213 TERMINATED
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock
Hospital Sirio-Libanes n=71
NCT04747795 COMPLETED
Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
Universitaire Ziekenhuizen KU Leuven n=301
NCT03452865 COMPLETED
Esomeprazole to Reduce Organ Failure in Sepsis
Università Vita-Salute San Raffaele n=300
NCT03835286 WITHDRAWN
Vitamin C to Reduce Vasopressor Dose in Septic Shock
Hospital Español de Mexico
NCT02990546 WITHDRAWN
Midodrine in the Recovery Phase of Septic Shock
University of Virginia
NCT04724044 COMPLETED
Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia
Hellenic Institute for the Study of Sepsis n=278
NCT05001854 SUSPENDED
Hemodynamics Effects of Fludrocortisone on the Pressor Response to Noradrenaline Septic Shock Patients
Rennes University Hospital n=40
NCT03280147 COMPLETED
7 Days Versus 14 Days of Antibiotics for Neonatal Sepsis
Indian Council of Medical Research n=261
NCT05558098 COMPLETED
Dapagliflozin in Patients With Critical Illness
Hospital Israelita Albert Einstein n=507
NCT04111822 COMPLETED
Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock
Cristina Martinez n=40
NCT05969327 COMPLETED
Role of Vitamin D Therapy in Recovery From Early Neonatal Sepsis (Randomized Controlled Trial)
Ain Shams University n=66
NCT02389036 COMPLETED
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
The George Institute n=20,010
NCT05293132 COMPLETED
Effect of Montelukast Versus Co Enzyme in Sepsis
Ain Shams University n=90
NCT03434028 COMPLETED
Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis
Massachusetts General Hospital n=1,563
NCT04742764 SUSPENDED
Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical Trial
University of Pecs n=135
NCT02867267 COMPLETED
The Efficacy and Safety of Ta1 for Sepsis
Sun Yat-sen University n=1,106
NCT04643639 COMPLETED
Assessing the Effects of CytoSorb Hemoperfusion on the Development on Immunoparalysis
Radboud University Medical Center n=24
NCT04446871 COMPLETED
Methylene Blue in Early Septic Shock
Hospital Civil de Guadalajara n=91
NCT05596942 COMPLETED
Evaluating the Efficacy of Channa Striata in Stabilizing eNOS in Patients With Septic.
Universitas Sebelas Maret n=42
NCT04088591 WITHDRAWN
High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
Virginia Commonwealth University
NCT03680274 COMPLETED
Lessening Organ Dysfunction With VITamin C
Université de Sherbrooke n=872
NCT03199547 COMPLETED
Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death
London School of Hygiene and Tropical Medicine n=11,985
NCT03380507 TERMINATED
Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock
Hamad Medical Corporation n=106
NCT04346693 COMPLETED
An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19
Burnasyan Federal Medical Biophysical Center n=320
NCT03872011 COMPLETED
Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
Northern Jiangsu People's Hospital n=408
NCT03338569 COMPLETED
Vitamin C and Septic Shock
University of Minnesota n=125
NCT02684487 WITHDRAWN
Vitamin D Status in Patients With Severe Sepsis
Massachusetts General Hospital
NCT03509350 COMPLETED
Vitamin C, Thiamine, and Steroids in Sepsis
Emory University n=501
NCT02508649 TERMINATED
Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial
Ferring Pharmaceuticals n=868
NCT03277677 COMPLETED
The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients
Chulalongkorn University n=116
NCT02330432 COMPLETED
Mycobacterium w in Patients With Severe Sepsis
Post Graduate Institute of Medical Education and Research, Chandigarh n=202
NCT03389555 COMPLETED
Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
Beth Israel Deaconess Medical Center n=205
NCT04508946 COMPLETED
Triple Therapy in Septic Shock Patients
Air Force Specialized Hospital, Cairo, Egypt n=94
NCT02714595 COMPLETED
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
Shionogi n=152
NCT03345992 COMPLETED
Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System
Hellenic Institute for the Study of Sepsis n=110
NCT04197115 COMPLETED
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
IMSS Hospital General de Zona 11, Piedras Negras n=19
NCT03828929 TERMINATED
Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock
New York Presbyterian Brooklyn Methodist Hospital n=3
NCT03844984 COMPLETED
Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients
Cairo University n=43
NCT03517501 WITHDRAWN
The Safety And Efficacy of ART-123 in Subjects With Sepsis and Coagulopathy
Asahi Kasei Pharma America Corporation
NCT03302650 SUSPENDED
Angiotensin II for Septic Shock Treatment
Cairo University n=20
NCT02748382 COMPLETED
Fluids in Sepsis and Septic Shock
McMaster University n=50
NCT03104140 COMPLETED
Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock
Cairo University n=26
NCT02338843 COMPLETED
A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension
La Jolla Pharmaceutical Company n=344
NCT02638545 COMPLETED
Hemodynamic Effects of Dexmedetomidine in Septic Shock
University of Roma La Sapienza n=37
NCT02954926 COMPLETED
Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis
Hormozgan University of Medical Sciences n=92

Data: ClinicalTrials.gov