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Data updated: Mar 10, 2026

DOXAPRAM HYDROCHLORIDE

DOXAPRAM HYDROCHLORIDE
Neurology Approved 1992-01-30
2
Indications
--
Phase 3 Trials
34
Years on Market

Details

Status
Prescription
First Approved
1992-01-30
Routes
INJECTION
Dosage Forms
INJECTABLE

DOXAPRAM HYDROCHLORIDE Approval History

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What DOXAPRAM HYDROCHLORIDE Treats

6 indications

DOXAPRAM HYDROCHLORIDE is approved for 6 conditions since its original approval in 1992. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Postanesthesia Respiratory Depression
  • Apnea
  • Drug-Induced Central Nervous System Depression
  • Chronic Obstructive Pulmonary Disease
  • Acute Respiratory Insufficiency
  • Acute Hypercapnia
Source: FDA Label

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

DOXAPRAM HYDROCHLORIDE FDA Label Details

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Indications & Usage

INDICATIONS & USAGE Postanesthesia When the possibility of airway obstruction and/or hypoxia have been eliminated, doxapram may be used to stimulate respiration in patients with drug-induced postanesthesia respiratory depression or apnea other than that due to muscle relaxant drugs. To pharmacologically stimulate deep breathing in the postoperative patient. (A quantitative method of assessing oxygenation, such as pulse oximetry, is recommended.) Drug-Induced Central Nervous System Depression Exercising care to prevent vomiting and aspiration, doxapram may be used to stimulate respiration, hast...

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.