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Data updated: Mar 10, 2026

EVEKEO

AMPHETAMINE SULFATE
Metabolic Approved 2012-08-09
1
Indication
--
Phase 3 Trials
13
Years on Market

Details

Status
Prescription
First Approved
2012-08-09
Routes
ORAL
Dosage Forms
TABLET

Companies

Active Ingredient: AMPHETAMINE SULFATE

EVEKEO Approval History

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What EVEKEO Treats

3 indications

EVEKEO is approved for 3 conditions since its original approval in 2012. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Narcolepsy
  • Attention Deficit Hyperactivity Disorder
  • Obesity
Source: FDA Label

EVEKEO Boxed Warning

ABUSE, MISUSE, AND ADDICTION Evekeo has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including amphetamine sulfate, can result in overdose and death (see OVERDOSAGE ), and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection. Before prescribing Evekeo, assess each patient's risk for abuse, misuse, and addiction. Educate patie...

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

EVEKEO FDA Label Details

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Indications & Usage

Evekeo ® (amphetamine sulfate tablets, USP) is indicated for: Narcolepsy Attention Deficit Disorder with Hyperactivity as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity. The diagnosis of the syndrome should not be made with finality when these symptoms are only of...

⚠️ BOXED WARNING

WARNING: ABUSE, MISUSE, AND ADDICTION Evekeo has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including amphetamine sulfate, can result in overdose and death (see OVERDOSAGE ), and this ...

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.