TheraRadar

Pharma Intelligence, Simplified

Data updated: Mar 10, 2026

PENTOXIFYLLINE

PENTOXIFYLLINE
Approved 1997-07-08
8
Indications
--
Phase 3 Trials
28
Years on Market

Details

Status
Prescription
First Approved
1997-07-08
Routes
ORAL
Dosage Forms
TABLET, EXTENDED RELEASE

PENTOXIFYLLINE Approval History

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What PENTOXIFYLLINE Treats

3 indications

PENTOXIFYLLINE is approved for 3 conditions since its original approval in 1997. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Intermittent Claudication
  • Chronic Occlusive Arterial Disease
  • Peripheral Vascular Disease
Source: FDA Label
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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

PENTOXIFYLLINE FDA Label Details

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Indications & Usage

Pentoxifylline extended-release tablets are indicated for the treatment of patients with intermittent claudication on the basis of chronic occlusive arterial disease of the limbs. Pentoxifylline can improve function and symptoms but is not intended to replace more definitive therapy, such as surgical bypass, or removal of arterial obstructions when treating peripheral vascular disease.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.