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Data updated: Mar 10, 2026

RELEXXII

METHYLPHENIDATE HYDROCHLORIDE
Metabolic Approved 2022-06-23
1
Indication
--
Phase 3 Trials
3
Years on Market

Details

Status
Prescription
First Approved
2022-06-23
Routes
ORAL
Dosage Forms
TABLET, EXTENDED RELEASE

Companies

Active Ingredient: METHYLPHENIDATE HYDROCHLORIDE

RELEXXII Approval History

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What RELEXXII Treats

1 indications

RELEXXII is approved for 1 conditions since its original approval in 2022. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Attention Deficit Hyperactivity Disorder
Source: FDA Label

RELEXXII Boxed Warning

ABUSE, MISUSE, AND ADDICTION RELEXXII has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including RELEXXII, can result in overdose and death [see Overdosage ( 10 )] , and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection. Before prescribing RELEXXII, assess each patient’s risk for abuse, misuse, and addiction. Educate patie...

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

RELEXXII FDA Label Details

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Indications & Usage

FDA Label (PDF)

RELEXXII is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults (up to the age of 65 years) and pediatric patients 6 years of age and older [ see Clinical Studies ] . Limitations of Use The use of RELEXXII is not recommended in pediatric patients younger than 6 years of age because they had higher plasma exposure and a higher incidence of adverse reactions (e.g., weight loss) than patients 6 years and older at the same dosage [see Warnings and Precautions , Use in Specific Populations ] . RELEXXII ® is a central nervous system (CNS) stimulant indicated for ...

⚠️ BOXED WARNING

WARNING: ABUSE, MISUSE, AND ADDICTION RELEXXII has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including RELEXXII, can result in overdose and death [see Overdosage ( 10 )] , and this ri...

RELEXXII Patents & Exclusivity

Latest Patent: Feb 2037

Patents (245 active)

US10695336 Expires Feb 3, 2037
US10265308 Expires Feb 3, 2037
US9855258 Expires Feb 3, 2037
US9827234 Expires Feb 3, 2037
US9707217 Expires Feb 3, 2037
+ 235 more patents
Source: FDA Orange Book

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.