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Data updated: Mar 10, 2026

TRANDOLAPRIL

TRANDOLAPRIL Angiotensin-converting Enzyme Inhibitors
Cardiovascular Approved 2006-12-12
5
Indications
--
Phase 3 Trials
19
Years on Market

Details

Status
Prescription
First Approved
2006-12-12
Routes
ORAL
Dosage Forms
TABLET

TRANDOLAPRIL Approval History

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What TRANDOLAPRIL Treats

4 indications

TRANDOLAPRIL is approved for 4 conditions since its original approval in 2006. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Hypertension
  • Heart Failure
  • Left Ventricular Dysfunction
  • Myocardial Infarction
Source: FDA Label

TRANDOLAPRIL Boxed Warning

FETAL TOXICITY When pregnancy is detected, discontinue trandolapril as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. (See WARNINGS: Fetal Toxicity .)...

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Key Completed Trials

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

TRANDOLAPRIL FDA Label Details

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Indications & Usage

Hypertension Trandolapril tablets USP are indicated for the treatment of hypertension. They may be used alone or in combination with other antihypertensive medication such as hydrochlorothiazide. Heart Failure Post Myocardial Infarction or Left-Ventricular Dysfunction Post Myocardial Infarction Trandolapril tablets USP are indicated in stable patients who have evidence of left-ventricular systolic dysfunction (identified by wall motion abnormalities) or who are symptomatic from congestive heart failure within the first few days after sustaining acute myocardial infarction. Administration of tr...

โš ๏ธ BOXED WARNING

WARNING: FETAL TOXICITY When pregnancy is detected, discontinue trandolapril as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. (See WARNINGS: Fetal Toxicity .)...

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.