TheraRadar

Pharma Intelligence, Simplified

Data updated: Mar 10, 2026

TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE

TRANDOLAPRIL Angiotensin-converting Enzyme Inhibitors
Cardiovascular Approved 2010-05-05
Jump to: Indications Approvals Trials Competitors Similar Safety Patents
3
Indications
--
Phase 3 Trials
15
Years on Market

Details

Status
Prescription
First Approved
2010-05-05
Routes
ORAL
Dosage Forms
TABLET, EXTENDED RELEASE

Companies

GLENMARK PHARMS LTD
Active Ingredient: TRANDOLAPRIL , VERAPAMIL HYDROCHLORIDE

TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE Approval History

Loading approval history...

What TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE Treats

1 indications

TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE is approved for 1 conditions since its original approval in 2010. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Hypertension
Source: FDA Label

TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE Boxed Warning

FETAL TOXICITY • When pregnancy is detected, discontinue trandolapril and verapamil hydrochloride extended-release tablets as soon as possible. • Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus (see WARNINGS: Fetal Toxicity ) ....

Drugs Similar to TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

ACEBUTOLOL HYDROCHLORIDE
ACEBUTOLOL HYDROCHLORIDE
1 shared
AMNEAL PHARM
Shared indications:
Hypertension
ALDACTONE
SPIRONOLACTONE
1 shared
Pfizer
Shared indications:
Hypertension
ALISKIREN HEMIFUMARATE
ALISKIREN HEMIFUMARATE
1 shared
PH HEALTH
Shared indications:
Hypertension
AMILORIDE HYDROCHLORIDE
AMILORIDE HYDROCHLORIDE
1 shared
SIGMAPHARM LABS LLC
Shared indications:
Hypertension
AMLODIPINE BESYLATE AND ATORVASTATIN CALCIUM
AMLODIPINE BESYLATE
1 shared
Viatris
Shared indications:
Hypertension
AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE
AMLODIPINE BESYLATE
1 shared
Aurobindo Pharma
Shared indications:
Hypertension
AMLODIPINE BESYLATE AND VALSARTAN
AMLODIPINE BESYLATE
1 shared
ALEMBIC
Shared indications:
Hypertension
AMLODIPINE BESYLATE, VALSARTAN AND HYDROCHLOROTHIAZIDE
AMLODIPINE BESYLATE
1 shared
STRIDES PHARMA INTL
Shared indications:
Hypertension
ARBLI
LOSARTAN POTASSIUM
1 shared
SCIENTURE
Shared indications:
Hypertension
ATACAND
CANDESARTAN CILEXETIL
1 shared
ANI PHARMS
Shared indications:
Hypertension
ATACAND HCT
CANDESARTAN CILEXETIL
1 shared
ANI PHARMS
Shared indications:
Hypertension
ATENOLOL
ATENOLOL
1 shared
AIPING PHARM INC
Shared indications:
Hypertension
ATENOLOL AND CHLORTHALIDONE
ATENOLOL
1 shared
WATSON LABS
Shared indications:
Hypertension
AVAPRO
IRBESARTAN
1 shared
Sanofi
Shared indications:
Hypertension
AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE
AZILSARTAN KAMEDOXOMIL
1 shared
ALKEM LABS LTD
Shared indications:
Hypertension
AZOR
AMLODIPINE BESYLATE
1 shared
COSETTE
Shared indications:
Hypertension
BENAZEPRIL HYDROCHLORIDE
BENAZEPRIL HYDROCHLORIDE
1 shared
COREPHARMA
Shared indications:
Hypertension
BENICAR
OLMESARTAN MEDOXOMIL
1 shared
COSETTE
Shared indications:
Hypertension
BENICAR HCT
HYDROCHLOROTHIAZIDE
1 shared
COSETTE
Shared indications:
Hypertension
BISOPROLOL FUMARATE
BISOPROLOL FUMARATE
1 shared
UNICHEM
Shared indications:
Hypertension
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...
⭐

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

ClinicalTrials.gov ↗ Pro

Full development history with FDA approval milestones

Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE FDA Label Details

Pro

Indications & Usage

Trandolapril and verapamil hydrochloride extended-release tablets are indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension (see DOSAGE AND ADMINISTRATION ). In using trandolapril and verapamil hydrochloride extended-release tablets, consideration should be given to the fact that an angiotensin converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that trandolapril does not have si...

⚠️ BOXED WARNING

WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue trandolapril and verapamil hydrochloride extended-release tablets as soon as possible. • Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus (see WARNINGS: Fetal Toxicity ) ....

Want competitive intelligence?

See who's developing similar drugs and track their progress

View Pipeline Dashboard

Data Sources

FDA Approval: ANDA079135 → Label: DailyMed → Trials: ClinicalTrials.gov →

Data sourced from official FDA and NIH databases. Click links to verify on original sources.