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Pharma Intelligence, Simplified

Data updated: Mar 10, 2026

VYVANSE

LISDEXAMFETAMINE DIMESYLATE
Cardiovascular Approved 2007-02-23
11
Indications
--
Phase 3 Trials
2
Priority Reviews
19
Years on Market

Details

Status
Prescription
First Approved
2007-02-23
Routes
ORAL
Dosage Forms
CAPSULE, TABLET, CHEWABLE

Companies

Active Ingredient: LISDEXAMFETAMINE DIMESYLATE

VYVANSE Approval History

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What VYVANSE Treats

2 indications

VYVANSE is approved for 2 conditions since its original approval in 2007. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Attention Deficit Hyperactivity Disorder
  • Binge Eating Disorder
Source: FDA Label

VYVANSE Boxed Warning

ABUSE, MISUSE, AND ADDICTION VYVANSE has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including VYVANSE, can result in overdose and death [see Overdosage (10) ] , and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection. Before prescribing VYVANSE, assess each patient's risk for abuse, misuse, and addiction. Educate patients ...

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

VYVANSE FDA Label Details

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Indications & Usage

FDA Label (PDF)

VYVANSE ® is indicated for the treatment of: Attention Deficit Hyperactivity Disorder (ADHD) in adults and pediatric patients 6 years and older [see Clinical Studies ]. Moderate to severe binge eating disorder (BED) in adults [see Clinical Studies ] . VYVANSE is a central nervous system (CNS) stimulant indicated for the treatment of : Attention Deficit Hyperactivity Disorder (ADHD) in adults and pediatric patients 6 years and older Moderate to severe binge eating disorder (BED) in adults Limitations of Use : The use of VYVANSE is not recommended in pediatric patients younger than 6 years of ag...

⚠️ BOXED WARNING

WARNING: ABUSE, MISUSE, AND ADDICTION VYVANSE has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including VYVANSE, can result in overdose and death [see Overdosage (10) ] , and this risk ...

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.