TheraRadar

Pharma Intelligence, Simplified

Data updated: Mar 10, 2026

ZEJULA

NIRAPARIB TOSYLATE
Oncology Approved 2017-03-27
6
Indications
--
Phase 3 Trials
3
Priority Reviews
8
Years on Market

Details

Status
Prescription
First Approved
2017-03-27
Routes
ORAL
Dosage Forms
TABLET, CAPSULE

Companies

Active Ingredient: NIRAPARIB TOSYLATE

ZEJULA Approval History

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What ZEJULA Treats

3 indications

ZEJULA is approved for 3 conditions since its original approval in 2017. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Ovarian Cancer
  • Fallopian Tube Cancer
  • Primary Peritoneal Cancer
Source: FDA Label
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ZEJULA FDA Label Details

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Indications & Usage

FDA Label (PDF)

ZEJULA is a poly (ADP-ribose) polymerase (PARP) inhibitor indicated: • for the maintenance treatment of adult patients with advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to first-line platinum-based chemotherapy and whose cancer is associated with homologous recombination deficiency (HRD)-positive status defined by either o a deleterious or suspected deleterious BRCA mutation, and/or o genomic instability. • for the maintenance treatment of adult patients with deleterious or suspected deleterious germline BRCA -mutated recur...

ZEJULA Patents & Exclusivity

Latest Patent: Jan 2039
Exclusivity: Apr 2027

Patents (89 active)

US11730725 Expires Jan 25, 2039
US11673877 Expires Mar 27, 2038
US11091459 Expires Mar 27, 2038
US8859562 Expires Aug 4, 2031
US8071623 Expires Mar 27, 2031
US8436185 Expires Apr 24, 2029
US8143241 Expires Aug 12, 2027
US8071579 Expires Aug 12, 2027
+ 79 more patents

Exclusivity

ODE-277 Until Oct 2026
ODE-295 Until Apr 2027
Source: FDA Orange Book

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.