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Data updated: Mar 10, 2026

ACETAZOLAMIDE

ACETAZOLAMIDE Carbonic Anhydrase Inhibitors
Cardiovascular Approved 1974-07-18
29
Indications
--
Phase 3 Trials
51
Years on Market

ACETAZOLAMIDE Approval History

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What ACETAZOLAMIDE Treats

5 indications

ACETAZOLAMIDE is approved for 5 conditions since its original approval in 1974. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Edema
  • Congestive Heart Failure
  • Epilepsy
  • Glaucoma
  • Acute Mountain Sickness
Source: FDA Label

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ACETAZOLAMIDE FDA Label Details

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Indications & Usage

For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies (petit mal, unlocalized seizures); chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure. Acetazolamide Tablets are also indicated for the prevention or amelioration of symptoms associated with acute mountain sickness in climbers attempting rapid ascent and in those who are very susceptible to acute mountain sickness despite gradual ascent.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.